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Phase I COVID-19 Vaccines

This site presents an alphabetically-ordered list of COVID-19 vaccines that are currently in Phase I clinical trials as of June 26, 2021.

Current Phase I COVID-19 vaccines include:

Contents:

  1. ABNCoV2
  2. AdCOVID
  3. AdimrSC-2f
  4. bacTRL-Spike
  5. BBV154
  6. ChAdV68-S
  7. ChulaCov19
  8. COH04S1
  9. CORVax12
  10. CoV2 SAM
  11. CoV2-OGEN1
  12. CoVepiT
  13. COVID-19 aAPC vaccine
  14. COVID-19 inactivated vaccine by The Scientific and Technological Research Council of Turkey (TÜBITAK)
  15. COVID-19 mRNA vaccine by Shanghai East Hospital and Stemirna Therapeutics
  16. COVID-19 rNDV vector vaccine by Laboratorio Avi-Mex
  17. COVID-19 VLP vaccine by the Scientific and Technological Research Council of Turkey
  18. COVIGEN
  19. Covigenix VAX-001
  20. COVI-VAC
  21. HDT-301
  22. IMP CoVac-1
  23. Koçak-19 Inaktif Adjuvanlı COVID-19 Vaccine
  24. LNP-nCoV saRNA-02
  25. LNP-nCoVsaRNA
  26. MF59-adjuvanted SARS-CoV-2 Sclamp vaccine
  27. mRNA-1283
  28. MV-014-212
  29. MVA-SARS-2-S
  30. NBP2001
  31. PTX-COVID19-B
  32. ReCOV
  33. SC-Ad6-1
  34. SpFN
  35. VXA-CoV2-1


  1. ABNCoV2
    • Clinical trial ID:
      • Phase I: NCT04839146
        • Age subgroups: 18-55 years
        • Location: Netherlands
    • Type: Virus like particle vaccine
    • Manufacturer: Radboud University
    • VIOLIN: 5865
    • VO: VO_0005255
  2. AdCOVID
    • Clinical trial ID:
      • Phase I: NCT04679909
        • Age subgroups: 18-55 years
        • Location: USA
    • Type: Recombinant vector vaccine
    • Manufacturer: Altimmune, Inc.
    • VIOLIN: 5835
    • VO: VO_0005153
  3. AdimrSC-2f
    • Clinical trial ID:
      • Phase I: NCT04522089
        • Age subgroups: 20-60 years
        • Location: Taiwan
    • Type: Subunit vaccine
    • Manufacturer: Adimmune Corporation
    • VO: VO_0005173
  4. bacTRL-Spike
    • Clinical trial ID:
      • Phase I: NCT04334980
        • Age subgroups: 18-59 years
        • Location: Australia
    • Type: DNA vaccine
    • Manufacturer: Symvivo
    • VIOLIN: 5817
    • VO: VO_0005174
  5. BBV154
    • Clinical trial ID:
      • Phase I: NCT04751682
        • Age subgroups: 18-60 years
        • Location: India
    • Type: Recombinant vector vaccine
    • Manufacturer: Bharat Biotech International Limited
    • VIOLIN: 5817
    • VO: VO_0005174
  6. ChAdV68-S
    • Clinical trial ID:
      • Phase I: NCT04760743
        • Age subgroups: 18-60 years, 61-99 years
        • Location: USA
    • Type: Recombinant vector vaccine
    • Manufacturer: Gritstone Oncology
    • VIOLIN: 5845
  7. ChulaCov19
    • Clinical trial ID:
      • Phase I: NCT04566276
        • Age subgroups:
          • Phase I: 18-55 years, 65-75 years
          • Phase II: 18-55 years, 65-75 years
        • Location: Australia
    • Type: mRNA vaccine
    • Manufacturer: Chulalongkorn University
    • VIOLIN: 5818
    • VO: VO_0005175
  8. COH04S1
    • Clinical trial ID:
      • Phase I: NCT04639466
        • Age subgroups: 18-55 years
        • Location: USA
    • Type: Recombinant vector vaccine
    • Manufacturer: City of Hope Medical Center
    • Publications
    • Chiuppesi et al. Development of a multi-antigenic SARS-CoV-2 vaccine candidate using a synthetic poxvirus platform. Nat Commun. 2020; 11(1); 6121. [PubMed: 33257686].
    • VIOLIN: 5819
    • VO: VO_0005176
  9. CORVax12
    • Clinical trial ID:
      • Phase I: NCT04627675
        • Age subgroups: 18-50 years, 60 years and above
        • Location: USA
    • Type: DNA vaccine
    • Manufacturer: Providence Health & Services, OncoSec Medical Inc.
    • VIOLIN: 5820
    • VO: VO_0005183
  10. CoV2 SAM
    • Clinical trial ID:
      • Phase I: NCT04758962
        • Age subgroups: 18-50 years
        • Location: USA
    • Type: mRNA vaccine
    • Manufacturer: GlaxoSmithKline
    • VIOLIN: 5842
    • VO: VO_0005156
  11. CoV2-OGEN1
    • Clinical trial ID:
      • Phase I: NCT04893512
        • Age subgroups: 18-56 years
        • Location: New Zealand
    • Type: Subunit vaccine
    • Manufacturer: US Specialty Formulations, VaxForm
    • VIOLIN: 5872
    • VO: VO_0005263
  12. CoVepiT
    • Clinical trial ID:
      • Phase I: NCT04885361
        • Age subgroups: 18-45 years
        • Location: Belgium
    • Type: Subunit vaccine
    • Manufacturer: OSE Immunotherapeutics
    • VIOLIN: 5870
    • VO: VO_0005261
  13. COVID-19 aAPC vaccine
    • Clinical trial ID:
      • Phase I: NCT04299724
        • Age subgroups: 6 months to 80 years
        • Location: China
    • Type: Recombinant vector vaccine
    • Manufacturer: Shenzhen Geno-Immune Medical Institute
    • VIOLIN: 5821
    • VO: VO_0005184
  14. COVID-19 inactivated vaccine by The Scientific and Technological Research Council of Turkey (TÜBITAK)
    • Clinical trial ID:
      • Phase I: NCT04866069
        • Age subgroups: 18-45 years
        • Location: Turkey
    • Type: Inactivated or "killed" vaccine
    • Manufacturer: The Scientific and Technological Research Council of Turkey (TÜBITAK)
    • VIOLIN: 5867
    • VO: VO_0005257
  15. COVID-19 mRNA vaccine by Shanghai East Hospital and Stemirna Therapeutics
    • Clinical trial ID:
    • Type: mRNA vaccine
    • Manufacturer: Shanghai East Hospital and Stemirna Therapeutics
    • VIOLIN: 5869
    • VO: VO_0005260
  16. COVID-19 rNDV vector vaccine by Laboratorio Avi-Mex
    • Clinical trial ID:
      • Phase I: NCT04871737
        • Age subgroups: 18-55 years
        • Location: Mexico
    • Type: Recombinant vector vaccine
    • Manufacturer: Laboratorio Avi-Mex
    • VIOLIN: 5822
    • VO: VO_0005259
  17. COVID-19 VLP vaccine by the Scientific and Technological Research Council of Turkey
    • Clinical trial ID:
      • Phase I: NCT04818281
        • Age subgroups: 18-59 years
        • Location: Turkey
    • Type: Virus like particle vaccine
    • Manufacturer: The Scientific and Technological Research Council of Turkey
    • VIOLIN: 5862
    • VO: VO_0005251
  18. COVIGEN
    • Clinical trial ID:
      • Phase I: NCT04742842
        • Age subgroups: 18-75 years
        • Location: Australia
    • Type: DNA vaccine
    • Manufacturer: University of Sydney, Bionet Co., Ltd, Technovalia
    • VIOLIN: 5837
    • VO: VO_0005231
  19. Covigenix VAX-001
    • Clinical trial ID:
      • Phase I: NCT04591184
        • Age subgroups: 18-54 years, 65-84 years
        • Location: Canada
    • Type: DNA vaccine
    • Manufacturer: Entos Pharmaceuticals
    • VIOLIN: 5823
    • VO: VO_0005186
  20. COVI-VAC
    • Clinical trial ID:
      • Phase I: NCT04619628
        • Age subgroups: 18-30 years
        • Location: UK
    • Type: Live, attenuated vaccine
    • Manufacturer: Codagenix, Inc.
    • VIOLIN: 5824
    • VO: VO_0005187
  21. HDT-301
    • Clinical trial ID:
      • Phase I: NCT04844268
        • Age subgroups: 18-55 years
        • Location: Unknown
    • Type: mRNA vaccine
    • Manufacturer: SENAI CIMATEC
    • VIOLIN: 5866
    • VO: VO_0005256
  22. IMP CoVac-1
    • Clinical trial ID:
      • Phase I: NCT04546841
        • Age subgroups: 18-55 years, 56-74 years, 75 years and above
        • Location: Germany
    • Type: Subunit vaccine
    • Manufacturer: University Hospital Tuebingen
    • VIOLIN: 5826
    • VO: VO_0005190
  23. Koçak-19 Inaktif Adjuvanlı COVID-19 Vaccine
    • Clinical trial ID:
      • Phase I: NCT04838080
        • Age subgroups: 18-55 years
        • Location: Turkey
    • Type: Inactivated or "killed" vaccine
    • Manufacturer: Kocak Farma
    • VIOLIN: 5860
    • VO: VO_0005253
  24. LNP-nCoV saRNA-02
    • Clinical trial ID:
      • Phase I: NCT04934111
        • Age subgroups: 18-45 years
        • Location: Uganda
    • Type: RNA vaccine
    • Manufacturer: MRC/UVRI and LSHTM Uganda Research Unit
    • VIOLIN: 5875
    • VO: VO_0005276
  25. LNP-nCoVsaRNA
    • Other names: COVAC1
    • Clinical trial ID:
    • Type: RNA vaccine
    • Manufacturer: Imperial College London, Morningside Ventures
    • Publications:
      • McKay et al. Self-amplifying RNA SARS-CoV-2 lipid nanoparticle vaccine candidate induces high neutralizing antibody titers in mice. Nat Commun. 2020; 11(1); 3523. [PubMed: 32647131].
    • VIOLIN: 5771
    • VO: VO_0005156
  26. MF59-adjuvanted SARS-CoV-2 Sclamp vaccine
    • Clinical trial ID:
      • Phase I: NCT04495933
        • Age subgroups: 18-55 years, 56 years and above
        • Location: Australia
    • Type: mRNA vaccine
    • Manufacturer: University of Queensland
    • Publications:
      • Chappell et al. Safety and immunogenicity of an MF59-adjuvanted spike glycoprotein-clamp vaccine for SARS-CoV-2: a randomised, double-blind, placebo-controlled, phase 1 trial. Lancet Infect Dis.. 2021 Apr 19:S1473-3099(21)00200-0. [PubMed: 33887208].
    • VIOLIN: 5861
    • VO: VO_0005258
  27. mRNA-1283
    • Clinical trial ID:
      • Phase I: NCT04813796
        • Age subgroups: 18-55 years
        • Location: USA
    • Type: mRNA vaccine
    • Manufacturer: Moderna
    • VIOLIN: 5868
    • VO: VO_0005185
  28. MV-014-212
    • Clinical trial ID:
      • Phase I: NCT04798001
        • Age subgroups: 18-55 years, 56-69 years
          • Unvaccinated Healthy Adults 18-55 years
          • Unvaccinated Healthy Adults 56-69 years
        • Location: USA
    • Type: Live, attenuated vaccine
    • Manufacturer: Meissa Vaccines, Inc.
    • VIOLIN: 5851
    • VO: VO_0005240
  29. MVA-SARS-2-S
    • Clinical trial ID:
      • Phase I: NCT04569383
        • Age subgroups: 18-55 years
        • Location: Germany
    • Type: Recombinant vector vaccine
    • Manufacturer: Universitätsklinikum Hamburg-Eppendorf, Ludwig-Maximilians - University of Munich
    • VIOLIN: 5827
    • VO: VO_0005191
  30. NBP2001
    • Clinical trial ID:
      • Phase I: NCT04760743
        • Age subgroups: 19-55 years
        • Location: South Korea
    • Type: Subunit vaccine
    • Manufacturer: SK Bioscience Co., Ltd.
    • VIOLIN: 5844
    • VO: VO_0005234
  31. PTX-COVID19-B
    • Clinical trial ID:
      • Phase I: NCT04765436
        • Age subgroups: 18-64 years
        • Location: Canada
    • Type: mRNA vaccine
    • Manufacturer: Providence Therapeutics
    • VIOLIN: 5840
    • VO: VO_0005236
  32. ReCOV
    • Clinical trial ID:
      • Phase I: NCT04818801
        • Age subgroups: 18-55 years, 56-80 years
        • Location: New Zealand
    • Type: Subunit vaccine
    • Manufacturer: Jiangsu Rec-Biotechnology
    • VIOLIN: 5863
    • VO: VO_0005252
  33. SC-Ad6-1
    • Clinical trial ID:
      • Phase I: NCT04839042
        • Age subgroups: 18-55 years
        • Location: Australia
    • Type: Recombinant vector vaccine
    • Manufacturer: Tetherex Pharmaceuticals Corporation
    • VIOLIN: 5864
    • VO: VO_0005254
  34. SpFN
    • Clinical trial ID:
      • Phase I: NCT04784767
        • Age subgroups: 18-55 years
        • Location: USA
    • Type: Subunit vaccine
    • Manufacturer: Walter Reed Army Institute of Research
    • VIOLIN: 5847
    • VO: VO_0005237
  35. VXA-CoV2-1
    • Clinical trial ID:
      • Phase I: NCT04563702
        • Age subgroups: 18-54 years
        • Location: USA
    • Type: Recombinant vector vaccine
    • Manufacturer: Vaxart
    • VIOLIN: 5832
    • VO: VO_0005196

Provenance: All data in Cov19VaxKB originates from manual curation of reliable resources.

Note: The page was updated on June 26, 2021. We plan to update this page on a weekly or even a daily basis. Please provide us with any new information that you believe would be useful if included on the website.