|
|
Phase I COVID-19 Vaccines
This site presents an alphabetically-ordered list of COVID-19 vaccines that are currently in Phase I clinical trials as of June 26, 2021.
Current Phase I COVID-19 vaccines include:
Contents:
- ABNCoV2
- AdCOVID
- AdimrSC-2f
- bacTRL-Spike
- BBV154
- ChAdV68-S
- ChulaCov19
- COH04S1
- CORVax12
- CoV2 SAM
- CoV2-OGEN1
- CoVepiT
- COVID-19 aAPC vaccine
- COVID-19 inactivated vaccine by The Scientific and Technological Research Council of Turkey (TÜBITAK)
- COVID-19 mRNA vaccine by Shanghai East Hospital and Stemirna Therapeutics
- COVID-19 rNDV vector vaccine by Laboratorio Avi-Mex
- COVID-19 VLP vaccine by the Scientific and Technological Research Council of Turkey
- COVIGEN
- Covigenix VAX-001
- COVI-VAC
- HDT-301
- IMP CoVac-1
- Koçak-19 Inaktif Adjuvanlı COVID-19 Vaccine
- LNP-nCoV saRNA-02
- LNP-nCoVsaRNA
- MF59-adjuvanted SARS-CoV-2 Sclamp vaccine
- mRNA-1283
- MV-014-212
- MVA-SARS-2-S
- NBP2001
- PTX-COVID19-B
- ReCOV
- SC-Ad6-1
- SpFN
- VXA-CoV2-1
- ABNCoV2
- Clinical trial ID:
- Phase I: NCT04839146
- Age subgroups: 18-55 years
- Location: Netherlands
- Type: Virus like particle vaccine
- Manufacturer: Radboud University
- VIOLIN: 5865
- VO: VO_0005255
- AdCOVID
- Clinical trial ID:
- Phase I: NCT04679909
- Age subgroups: 18-55 years
- Location: USA
- Type: Recombinant vector vaccine
- Manufacturer: Altimmune, Inc.
- VIOLIN: 5835
- VO: VO_0005153
- AdimrSC-2f
- Clinical trial ID:
- Phase I: NCT04522089
- Age subgroups: 20-60 years
- Location: Taiwan
- Type: Subunit vaccine
- Manufacturer: Adimmune Corporation
- VO: VO_0005173
- bacTRL-Spike
- Clinical trial ID:
- Phase I: NCT04334980
- Age subgroups: 18-59 years
- Location: Australia
- Type: DNA vaccine
- Manufacturer: Symvivo
- VIOLIN: 5817
- VO: VO_0005174
- BBV154
- Clinical trial ID:
- Phase I: NCT04751682
- Age subgroups: 18-60 years
- Location: India
- Type: Recombinant vector vaccine
- Manufacturer: Bharat Biotech International Limited
- VIOLIN: 5817
- VO: VO_0005174
- ChAdV68-S
- Clinical trial ID:
- Phase I: NCT04760743
- Age subgroups: 18-60 years, 61-99 years
- Location: USA
- Type: Recombinant vector vaccine
- Manufacturer: Gritstone Oncology
- VIOLIN: 5845
- ChulaCov19
- Clinical trial ID:
- Phase I: NCT04566276
- Age subgroups:
- Phase I: 18-55 years, 65-75 years
- Phase II: 18-55 years, 65-75 years
- Location: Australia
- Type: mRNA vaccine
- Manufacturer: Chulalongkorn University
- VIOLIN: 5818
- VO: VO_0005175
- COH04S1
- Clinical trial ID:
- Phase I: NCT04639466
- Age subgroups: 18-55 years
- Location: USA
- Type: Recombinant vector vaccine
- Manufacturer: City of Hope Medical Center
- Publications
- Chiuppesi et al. Development of a multi-antigenic SARS-CoV-2 vaccine candidate using a synthetic poxvirus platform. Nat Commun. 2020; 11(1); 6121. [PubMed: 33257686].
- VIOLIN: 5819
- VO: VO_0005176
- CORVax12
- Clinical trial ID:
- Phase I: NCT04627675
- Age subgroups: 18-50 years, 60 years and above
- Location: USA
- Type: DNA vaccine
- Manufacturer: Providence Health & Services, OncoSec Medical Inc.
- VIOLIN: 5820
- VO: VO_0005183
- CoV2 SAM
- Clinical trial ID:
- Phase I: NCT04758962
- Age subgroups: 18-50 years
- Location: USA
- Type: mRNA vaccine
- Manufacturer: GlaxoSmithKline
- VIOLIN: 5842
- VO: VO_0005156
- CoV2-OGEN1
- Clinical trial ID:
- Phase I: NCT04893512
- Age subgroups: 18-56 years
- Location: New Zealand
- Type: Subunit vaccine
- Manufacturer: US Specialty Formulations, VaxForm
- VIOLIN: 5872
- VO: VO_0005263
- CoVepiT
- Clinical trial ID:
- Phase I: NCT04885361
- Age subgroups: 18-45 years
- Location: Belgium
- Type: Subunit vaccine
- Manufacturer: OSE Immunotherapeutics
- VIOLIN: 5870
- VO: VO_0005261
- COVID-19 aAPC vaccine
- Clinical trial ID:
- Phase I: NCT04299724
- Age subgroups: 6 months to 80 years
- Location: China
- Type: Recombinant vector vaccine
- Manufacturer: Shenzhen Geno-Immune Medical Institute
- VIOLIN: 5821
- VO: VO_0005184
- COVID-19 inactivated vaccine by The Scientific and Technological Research Council of Turkey (TÜBITAK)
- Clinical trial ID:
- Phase I: NCT04866069
- Age subgroups: 18-45 years
- Location: Turkey
- Type: Inactivated or "killed" vaccine
- Manufacturer: The Scientific and Technological Research Council of Turkey (TÜBITAK)
- VIOLIN: 5867
- VO: VO_0005257
- COVID-19 mRNA vaccine by Shanghai East Hospital and Stemirna Therapeutics
- Clinical trial ID:
- Type: mRNA vaccine
- Manufacturer: Shanghai East Hospital and Stemirna Therapeutics
- VIOLIN: 5869
- VO: VO_0005260
- COVID-19 rNDV vector vaccine by Laboratorio Avi-Mex
- Clinical trial ID:
- Phase I: NCT04871737
- Age subgroups: 18-55 years
- Location: Mexico
- Type: Recombinant vector vaccine
- Manufacturer: Laboratorio Avi-Mex
- VIOLIN: 5822
- VO: VO_0005259
- COVID-19 VLP vaccine by the Scientific and Technological Research Council of Turkey
- Clinical trial ID:
- Phase I: NCT04818281
- Age subgroups: 18-59 years
- Location: Turkey
- Type: Virus like particle vaccine
- Manufacturer: The Scientific and Technological Research Council of Turkey
- VIOLIN: 5862
- VO: VO_0005251
- COVIGEN
- Clinical trial ID:
- Phase I: NCT04742842
- Age subgroups: 18-75 years
- Location: Australia
- Type: DNA vaccine
- Manufacturer: University of Sydney, Bionet Co., Ltd, Technovalia
- VIOLIN: 5837
- VO: VO_0005231
- Covigenix VAX-001
- Clinical trial ID:
- Phase I: NCT04591184
- Age subgroups: 18-54 years, 65-84 years
- Location: Canada
- Type: DNA vaccine
- Manufacturer: Entos Pharmaceuticals
- VIOLIN: 5823
- VO: VO_0005186
- COVI-VAC
- Clinical trial ID:
- Phase I: NCT04619628
- Age subgroups: 18-30 years
- Location: UK
- Type: Live, attenuated vaccine
- Manufacturer: Codagenix, Inc.
- VIOLIN: 5824
- VO: VO_0005187
- HDT-301
- Clinical trial ID:
- Phase I: NCT04844268
- Age subgroups: 18-55 years
- Location: Unknown
- Type: mRNA vaccine
- Manufacturer: SENAI CIMATEC
- VIOLIN: 5866
- VO: VO_0005256
- IMP CoVac-1
- Clinical trial ID:
- Phase I: NCT04546841
- Age subgroups: 18-55 years, 56-74 years, 75 years and above
- Location: Germany
- Type: Subunit vaccine
- Manufacturer: University Hospital Tuebingen
- VIOLIN: 5826
- VO: VO_0005190
- Koçak-19 Inaktif Adjuvanlı COVID-19 Vaccine
- Clinical trial ID:
- Phase I: NCT04838080
- Age subgroups: 18-55 years
- Location: Turkey
- Type: Inactivated or "killed" vaccine
- Manufacturer: Kocak Farma
- VIOLIN: 5860
- VO: VO_0005253
- LNP-nCoV saRNA-02
- Clinical trial ID:
- Phase I: NCT04934111
- Age subgroups: 18-45 years
- Location: Uganda
- Type: RNA vaccine
- Manufacturer: MRC/UVRI and LSHTM Uganda Research Unit
- VIOLIN: 5875
- VO: VO_0005276
- LNP-nCoVsaRNA
- Other names: COVAC1
- Clinical trial ID:
- Type: RNA vaccine
- Manufacturer: Imperial College London, Morningside Ventures
- Publications:
- McKay et al. Self-amplifying RNA SARS-CoV-2 lipid nanoparticle vaccine candidate induces high neutralizing antibody titers in mice. Nat Commun. 2020; 11(1); 3523. [PubMed: 32647131].
- VIOLIN: 5771
- VO: VO_0005156
- MF59-adjuvanted SARS-CoV-2 Sclamp vaccine
- Clinical trial ID:
- Phase I: NCT04495933
- Age subgroups: 18-55 years, 56 years and above
- Location: Australia
- Type: mRNA vaccine
- Manufacturer: University of Queensland
- Publications:
- Chappell et al. Safety and immunogenicity of an MF59-adjuvanted spike glycoprotein-clamp vaccine for SARS-CoV-2: a randomised, double-blind, placebo-controlled, phase 1 trial. Lancet Infect Dis.. 2021 Apr 19:S1473-3099(21)00200-0. [PubMed: 33887208].
- VIOLIN: 5861
- VO: VO_0005258
- mRNA-1283
- Clinical trial ID:
- Phase I: NCT04813796
- Age subgroups: 18-55 years
- Location: USA
- Type: mRNA vaccine
- Manufacturer: Moderna
- VIOLIN: 5868
- VO: VO_0005185
- MV-014-212
- Clinical trial ID:
- Phase I: NCT04798001
- Age subgroups: 18-55 years, 56-69 years
- Unvaccinated Healthy Adults 18-55 years
- Unvaccinated Healthy Adults 56-69 years
- Location: USA
- Type: Live, attenuated vaccine
- Manufacturer: Meissa Vaccines, Inc.
- VIOLIN: 5851
- VO: VO_0005240
- MVA-SARS-2-S
- Clinical trial ID:
- Phase I: NCT04569383
- Age subgroups: 18-55 years
- Location: Germany
- Type: Recombinant vector vaccine
- Manufacturer: Universitätsklinikum Hamburg-Eppendorf, Ludwig-Maximilians - University of Munich
- VIOLIN: 5827
- VO: VO_0005191
- NBP2001
- Clinical trial ID:
- Phase I: NCT04760743
- Age subgroups: 19-55 years
- Location: South Korea
- Type: Subunit vaccine
- Manufacturer: SK Bioscience Co., Ltd.
- VIOLIN: 5844
- VO: VO_0005234
- PTX-COVID19-B
- Clinical trial ID:
- Phase I: NCT04765436
- Age subgroups: 18-64 years
- Location: Canada
- Type: mRNA vaccine
- Manufacturer: Providence Therapeutics
- VIOLIN: 5840
- VO: VO_0005236
- ReCOV
- Clinical trial ID:
- Phase I: NCT04818801
- Age subgroups: 18-55 years, 56-80 years
- Location: New Zealand
- Type: Subunit vaccine
- Manufacturer: Jiangsu Rec-Biotechnology
- VIOLIN: 5863
- VO: VO_0005252
- SC-Ad6-1
- Clinical trial ID:
- Phase I: NCT04839042
- Age subgroups: 18-55 years
- Location: Australia
- Type: Recombinant vector vaccine
- Manufacturer: Tetherex Pharmaceuticals Corporation
- VIOLIN: 5864
- VO: VO_0005254
- SpFN
- Clinical trial ID:
- Phase I: NCT04784767
- Age subgroups: 18-55 years
- Location: USA
- Type: Subunit vaccine
- Manufacturer: Walter Reed Army Institute of Research
- VIOLIN: 5847
- VO: VO_0005237
- VXA-CoV2-1
- Clinical trial ID:
- Phase I: NCT04563702
- Age subgroups: 18-54 years
- Location: USA
- Type: Recombinant vector vaccine
- Manufacturer: Vaxart
- VIOLIN: 5832
- VO: VO_0005196
Provenance: All data in Cov19VaxKB originates from manual curation of reliable resources.
Note: The page was updated on June 26, 2021. We plan to update this page on a weekly or even a daily basis. Please provide us with any new information that you believe would be useful if included on the website.
|
