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Phase II COVID-19 Vaccines

This site presents an alphabetically-ordered list of COVID-19 vaccines that are currently in Phase II clinical trials as of September 4, 2021.

Current Phase II COVID-19 vaccines include:

Contents:

  1. 202-CoV
  2. AdCLD-CoV19
  3. AG0302-COVID19
  4. AKS-452
  5. ARCT-021
  6. AV-COVID-19
  7. BECOV2A
  8. CIGB-669
  9. COH04S1
  10. COVAC
  11. COVID-19 subunit vaccine by HIPRA
  12. COVID-19 subunit vaccine by National Vaccine and Serum Institute of China
  13. COVID-19 VLP vaccine by the Scientific and Technological Research Council of Turkey
  14. COVID-eVax
  15. COVIVAC
  16. DelNS1-2019-nCoV-RBD-OPT1
  17. DS-5670a
  18. EuCorVac-19
  19. EXG-5003
  20. FAKHRAVAC
  21. FINLAY-FR-1
  22. GLS-5310
  23. GX-19
  24. hAd5-COVID-19
  25. KBP-COVID-19
  26. KD-414
  27. LV-SMENP-DC
  28. mRNA-1273.351
  29. MRT5500
  30. MVA-SARS-2-ST
  31. NDV-HXP-S
  32. QazCoVac-P
  33. Razi Cov Pars
  34. RBD-HBsAg VLP
  35. S-268019
  36. SCB-2020S
  37. V-01
  38. VBI-2902a


  1. 202-CoV
    • Clinical trial ID:
      • Phase II: NCT04990544
        • Age subgroups: 18-59 years; 60 years and above
        • Location: China
      • Phase I: NCT04982068
        • Age subgroups: 18-59 years; 60 years and above
        • Location: China
    • Type: Subunit vaccine
    • Manufacturer: Shanghai Zerun Biotechnology, Walvax Biotechnology, CEPI
    • VIOLIN: 5835
    • VO: VO_0005320
  2. AdCLD-CoV19
    • Clinical trial ID:
      • Phase I/II: NCT04666012
        • Age subgroups: 19-64 years
        • Location: South Korea
    • Type: Recombinant vector vaccine
    • Manufacturer: Cellid Co., Ltd.
    • VIOLIN: 5800
    • VO: VO_0004996
  3. AG0302-COVID19
    • Clinical trial ID:
      • Phase I/II: NCT04993586
        • Age subgroups: 18 years and above
        • Location: Japan
    • Type: DNA vaccine
    • Manufacturer: AnGes, Inc.
    • VIOLIN: 5882
    • VO: VO_0005322
  4. AKS-452
    • Clinical trial ID:
      • Phase I/II: NCT04681092
        • Age subgroups: 18-55 years
        • Location: Netherlands
    • Type: Subunit vaccine
    • Manufacturer: University Medical Center Groningen, Akston Biosciences Inc.
    • VIOLIN: 5834
    • VO: VO_0004999
  5. ARCT-021
    • Other names: LUNAR-COV19
    • Clinical trial ID:
      • Phase II: NCT04728347
        • Age subgroups: 18-55 years (21-55 years in Singapore), 56 years and above
        • Location: USA, Singapore
      • Phase II: NCT04728347
        • Age subgroups: 21-80 years
        • Location: Singapore
      • Phase I/II: NCT04480957
        • Age subgroups:
          • Phase I: 21-55 years
          • Phase II: 21-55 years, 56-80 years
        • Location: Singapore
    • Type: mRNA vaccine
    • Manufacturer: Arcturus Therapeutics, Duke-NUS Medical School
    • VIOLIN: 5781
    • VO: VO_0005164
  6. AV-COVID-19
    • Clinical trial ID:
      • Phase II: NCT05007496
        • Age subgroups: 18 years and above
        • Location: Indonesia
      • Phase I/II: NCT04386252
        • Age subgroups: 18 years and above
        • Location: USA
    • Type: Recombinant vector vaccine
    • Manufacturer: Aivita Biomedical, Inc.
    • VIOLIN: 5801
    • VO: VO_0005079
  7. BECOV2A
    • Clinical trial ID:
      • Phase I/II: CTRI/2020/11/029032
        • Age subgroups:
          • Phase I: 18-55 years
          • Phase II: 18-65 years
        • Location: India
    • Type: Subunit vaccine
    • Manufacturer: Biological E
    • VIOLIN: 5802
    • VO: VO_0005081
  8. CIGB-669
    • Clinical trial ID:
      • Phase I/II: RPCEC00000345
        • Age subgroups:
          • Phase I: 19-54 years
            Phase II: 19-80 years
        • Location: Cuba
    • Type: Subunit vaccine
    • Manufacturer: Center for Genetic Engineering and Biotechnology (CIGB)
    • VIOLIN: 5804
    • VO: VO_0005083
  9. COH04S1
    • Clinical trial ID:
      • Phase II: NCT04977024
        • Age subgroups: 18 years and above
        • Location: USA
      • Phase I: NCT04639466
        • Age subgroups: 18-55 years
        • Location: USA
    • Type: Recombinant vector vaccine
    • Manufacturer: City of Hope Medical Center
    • Publications
      • Chiuppesi et al. Development of a multi-antigenic SARS-CoV-2 vaccine candidate using a synthetic poxvirus platform. Nat Commun. 2020; 11(1); 6121. [PubMed: 33257686].
    • VIOLIN: 5819
    • VO: VO_0005176
  10. COVAC
    • Clinical trial ID:
      • Phase I/II: NCT04702178
        • Age subgroups: 18-54 years, 55-69 years, 70 years and above
        • Location: Canada
    • Type: Subunit vaccine
    • Manufacturer: Vaccine and Infectious Disease Organization (VIDO), SEPPIC, Vaccine Formulation Institute (VFI)
    • VIOLIN: 5830
    • VO: VO_0005194
  11. COVID-19 subunit vaccine by HIPRA
    • Clinical trial ID:
      • Phase I/II: NCT05007509
        • Age subgroups: 18-39 years
        • Location: Spain
    • Type: Subunit vaccine
    • Manufacturer: Laboratorios Hipra, S.A.
    • VIOLIN: 5883
    • VO: VO_0005321
  12. COVID-19 subunit vaccine by National Vaccine and Serum Institute of China
    • Clinical trial ID:
      • Phase I/II: NCT04869592
        • Age subgroups:
          • Phase I: 3-8 years, 9-17 years, 18-59 years, 60-69 years, 70 years and above
          • Phase II: 3-8 years, 9-17 years, 18-59 years, 60-69 years, 70 years and above
        • Location: China
    • Type: Subunit vaccine
    • Manufacturer: National Vaccine and Serum Institute, China
    • VIOLIN: 5857
    • VO: VO_0005248
  13. COVID-19 VLP vaccine by the Scientific and Technological Research Council of Turkey
    • Clinical trial ID:
      • Phase II: NCT04962893
        • Age subgroups: 18-59 years
        • Location: Turkey
      • Phase I: NCT04818281
        • Age subgroups: 18-59 years
        • Location: Turkey
    • Type: Virus like particle vaccine
    • Manufacturer: The Scientific and Technological Research Council of Turkey
    • VIOLIN: 5862
    • VO: VO_0005251
  14. COVID-eVax
    • Clinical trial ID:
      • Phase I/II: NCT04788459
        • Age subgroups: 18-64 years, 65 years and above
        • Location: Italy
    • Type: DNA vaccine
    • Manufacturer: Takis, Rottapharm Biotech
    • VIOLIN: 5838
    • VO: VO_0005230
  15. COVIVAC
    • Clinical trial ID:
      • Phase I/II: NCT04830800
        • Age subgroups:
          • Phase I: 18-59 years
          • Phase II: 18-75 years
        • Location: Vietnam
    • Type: Recombinant vector vaccine
    • Manufacturer: Institute of Vaccines and Medical Biologicals, Vietnam
    • VIOLIN: 5855
    • VO: VO_0005246
  16. DelNS1-2019-nCoV-RBD-OPT1
    • Clinical trial ID:
    • Type: Recombinant vector vaccine
    • Manufacturer: University of Hong Kong, Xiamen University, Beijing Wantai Biological Pharmacy
    • VIOLIN: 5806
    • VO: VO_0005087
  17. DS-5670a
    • Clinical trial ID:
      • Phase I/II: NCT04821674
        • Age subgroups: 20-64 years, 65-74 years
        • Location: Japan
    • Type: mRNA vaccine
    • Manufacturer: Daiichi Sankyo Co., Ltd.
    • VIOLIN: 5854
    • VO: VO_0005245
  18. EuCorVac-19
    • Clinical trial ID:
      • Phase I/II: NCT04783311
        • Age subgroups:
          • Phase I: 19-50 years
          • Phase II: 19-75 years
        • Location: South Korea
    • Type: Subunit vaccine
    • Manufacturer: EuBiologics Co., Ltd.
    • VIOLIN: 5848
    • VO: VO_0005232
  19. EXG-5003
    • Clinical trial ID:
      • Phase I/II: NCT04863131
        • Age subgroups: 20-55 years
        • Location: Japan
    • Type: mRNA vaccine
    • Manufacturer: Elixirgen Therapeutics, Inc.
    • VIOLIN: 5858
    • VO: VO_0005249
  20. FAKHRAVAC
    • Other names: MIVAC
    • Clinical trial ID:
    • Type: Inactivated or "killed" vaccine
    • Manufacturer: Organization of Defensive Innovation and Research
    • VIOLIN: 5849
    • VO: VO_0005239
  21. FINLAY-FR-1
    • Clinical trial ID:
      • Phase II: IFV/COR/11
        • Age subgroups: 19-80 years
        • Location: Cuba
      • Phase I/II: IFV/COR/04
        • Age subgroups: 19-59 years, 60-80 years
        • Location: Cuba
    • Type: Subunit vaccine
    • Manufacturer: Instituto Finlay de Vacunas, Cuba
    • VIOLIN: 5853
    • VO: VO_0005244
  22. GLS-5310
    • Clinical trial ID:
      • Phase I/II: NCT04673149
        • Age subgroups:
          • Phase I: 19-50 years
          • Phase II: 19-65 years
        • Location: South Korea
    • Type: DNA vaccine
    • Manufacturer: GeneOne Life Science, Inc.
    • VIOLIN: 5807
    • VO: VO_0005089
  23. GX-19
    • Clinical trial ID:
      • Phase I/II: NCT04715997
        • Age subgroups: 18-55 years
        • Location: South Korea
      • Phase I/II: NCT04445389
        • Age subgroups: 18-50 years
        • Location: South Korea
    • Type: DNA vaccine
    • Manufacturer: Genexine
    • VIOLIN: 5788
    • VO: VO_0005170
  24. hAd5-COVID-19
    • Clinical trial ID:
      • Phase II: NCT04843722
        • Age subgroups: 18-80 years
        • Location: USA
      • Phase II: NCT04845191
        • Age subgroups: 18-80 years
        • Location: USA
      • Phase I: NCT04732468
        • Age subgroups: 18-55 years
        • Location: USA
      • Phase I: NCT04591717
        • Age subgroups: 18-55 years
        • Location: USA
      • Phase I: NCT04710303
        • Age subgroups: 18-50 years
        • Location: USA
    • Type: Recombinant vector vaccine
    • Manufacturer: ImmunityBio, Inc.; NantKwest Inc.
    • VIOLIN: 5825
    • VO: VO_0005189
  25. IMP CoVac-1
    • Clinical trial ID:
      • Phase I/II: NCT04954469
        • Age subgroups: 18 years and above
        • Location: Germany
      • Phase I: NCT04546841
        • Age subgroups: 18-55 years, 56-74 years, 75 years and above
        • Location: Germany
    • Type: Subunit vaccine
    • Manufacturer: University Hospital Tuebingen
    • VIOLIN: 5826
    • VO: VO_0005190
  26. KBP-COVID-19
    • Clinical trial ID:
      • Phase I/II: NCT04473690
        • Age subgroups: 18-49 years, 50-70 years
        • Location: USA
    • Type: Subunit vaccine
    • Manufacturer: Kentucky BioProcessing
    • VIOLIN: 5792
    • VO: VO_0005171
  27. KD-414
    • Clinical trial ID:
      • Phase I/II: jRCT2071200106
        • Age subgroups: 20-64 years, 65 years and above
        • Location: Japan
    • Type: Inactivated or "killed" vaccine
    • Manufacturer: KM Biologics Co., Ltd.
    • VIOLIN: 5859
    • VO: VO_0005250
  28. LV-SMENP-DC
    • Clinical trial ID:
      • Phase I/II: NCT04276896
        • Age subgroups: 6 months to 80 years
        • Location: China
    • Type: Recombinant vector vaccine
    • Manufacturer: Shenzhen Geno-Immune Medical Institute
    • VIOLIN: 5808
    • VO: VO_0005091
  29. mRNA-1273.351
    • Clinical trial ID:
      • Phase II: NCT04847050
        • Age subgroups: 18 years and above
        • Location: USA
      • Phase I: NCT04785144
        • Age subgroups
          • Cohort 1: Previously vaccinated people 18 years and above
          • Cohort 2: Unvaccinated people 18-55 years
        • Location: USA
    • Type: mRNA vaccine
    • Manufacturer: Moderna, NIAID
    • VIOLIN: 5846
    • VO: VO_0005233
  30. MRT5500
    • Clinical trial ID:
      • Phase I/II: NCT04798027
        • Age subgroups: 18 years and above
        • Location: USA
    • Type: mRNA vaccine
    • Manufacturer: Sanofi Pasteur, Translate Bio
    • VIOLIN: 5850
    • VO: VO_0005241
  31. MVA-SARS-2-ST
    • Clinical trial ID:
      • Phase I/II: NCT04895449
        • Age subgroups:
          • Phase I: 18-64 years
          • Phase II: 18 years and above
        • Location: Germany
    • Type: Recombinant vector vaccine
    • Manufacturer: German Center for Infection Research
    • VIOLIN: 5871
    • VO: VO_0005262
  32. NDV-HXP-S
    • Clinical trial ID:
      • Phase I/II: NCT04764422
        • Age subgroups:
          • Phase I: 18-59 years
          • Phase II: 18-75 years
        • Location: Thailand
    • Type: Recombinant vector vaccine
    • Manufacturer: Icahn School of Medicine at Mount Sinai, Mahidol University
    • Publications:
      • Sun et al. Newcastle disease virus (NDV) expressing the spike protein of SARS-CoV-2 as a live virus vaccine candidate. EBioMedicine. 2020; 62; 103132. [PubMed: 33232870].
    • VIOLIN: 5841
    • VO: VO_0005235
  33. QazCoVac-P
    • Clinical trial ID:
      • Phase I/II: NCT04930003
        • Age subgroups:
          • Phase I: 18-50 years
          • Phase II: 18 years and above
        • Location: Kazakhstan
    • Type: Subunit vaccine
    • Manufacturer: Research Institute for Biological Safety Problems
    • VIOLIN: 5874
    • VO: VO_0005273
  34. Razi Cov Pars
    • Clinical trial ID:
    • Type: Subunit vaccine
    • Manufacturer: Razi Vaccine and Serum Research Institute
    • VIOLIN: 5779
    • VO: VO_0005226
  35. RBD-HBsAg VLP
    • Clinical trial ID:
      • Phase I/II: ACTRN12620001308987
        • Age subgroups:
          • Phase I: 18-45 years
          • Phase II: 18-79 years
        • Location: Australia
      • Phase I/II: ACTRN12620000817943
        • Age subgroups:
          • Phase I: 18-45 years
          • Phase II: 18-79 years
        • Location: Australia
    • Type: Virus Like Particle
    • Manufacturer: Serum Institute of India, Accelegen Pty
    • VIOLIN: 5811
    • VO: VO_0005094
  36. S-268019
    • Clinical trial ID:
      • Phase I/II: jRCT2051200092
        • Age subgroups: 20-64 years
        • Location: Japan
    • Type: Subunit vaccine
    • Manufacturer: Shionogi
    • VIOLIN: 5813
    • VO: VO_0005096
  37. SCB-2020S
    • Clinical trial ID:
      • Phase II: NCT04950751
        • Age subgroups: 18 years and above
        • Location: Unknown
    • Type: Subunit vaccine
    • Manufacturer: Clover Biopharmaceuticals AUS Pty Ltd
    • VIOLIN: 5879
    • VO: VO_0005315
  38. V-01
    • Clinical trial ID:
      • Phase II: ChiCTR2100045107
        • Age subgroups: 18-59 years, 60-69 years, 70 years and above
        • Location: China
    • Type: Subunit vaccine
    • Manufacturer: Livzon Mabpharm Inc.
    • VIOLIN: 5856
    • VO: VO_0005247
  39. VBI-2902a
    • Clinical trial ID:
      • Phase I/II: NCT04773665
        • Age subgroups:
          • Phase I: 18-54 years
          • Phase II: 18-54 years, 55-65 years, 66 years and above
        • Location: Canada
    • Type: Virus Like Particle
    • Manufacturer: VBI Vaccines Inc.
    • VIOLIN: 5843
    • VO: VO_0005238

Provenance: All data in Cov19VaxKB originates from manual curation of reliable resources

Note: The page was updated on September 4, 2021. We plan to update this page on a weekly or even a daily basis. Please provide us with any new information that you believe would be useful if included on the website.