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Phase II COVID-19 Vaccines

This site presents an alphabetically-ordered list of COVID-19 vaccines that are currently in Phase II clinical trials as of May 31, 2021.

Current Phase II COVID-19 vaccines include:

Contents:

1. AdCLD-CoV19
2. AKS-452
3. ARCT-021
4. AV-COVID-19
5. BECOV2A
6. CIGB-669
7. COVAC
8. COVID-19 subunit vaccine by National Vaccine and Serum Institute of China
9. COVID-eVax
10. COVIVAC
11. DelNS1-2019-nCoV-RBD-OPT1
12. DS-5670a
13. ERUCOV-VAC
14. EuCorVac-19
15. EXG-5003
16. FINLAY-FR-1
17. GBP510
18. GLS-5310
19. GX-19
20. hAd5-COVID-19
21. IIBR-100
22. KBP-COVID-19
23. KD-414
24. LV-SMENP-DC
25. mRNA-1273.351
26. MRT5500
27. MVA-SARS-2-ST
28. MVC-COV1901
29. Nanocovax
30. NDV-HXP-S
31. Razi Cov Pars
32. RBD-HBsAg VLP
33. S-268019
34. SpikoGen
35. V-01
36. VBI-2902a

1. AdCLD-CoV19
• Clinical trial ID:
• Phase I/II: NCT04666012
• Age subgroups: 19-64 years
• Location: South Korea
• Type: Recombinant vector vaccine
• Manufacturer: Cellid Co., Ltd.
• VIOLIN: 5800
• VO: VO_0004996
2. AKS-452
• Clinical trial ID:
• Phase I/II: NCT04681092
• Age subgroups: 18-55 years
• Location: Netherlands
• Type: Subunit vaccine
• Manufacturer: University Medical Center Groningen, Akston Biosciences Inc.
• VIOLIN: 5834
• VO: VO_0004999
3. ARCT-021
• Other names: LUNAR-COV19
• Clinical trial ID:
• Phase II: NCT04728347
• Age subgroups: 18-55 years (21-55 years in Singapore), 56 years and above
• Location: USA, Singapore
• Phase II: NCT04728347
• Age subgroups: 21-80 years
• Location: Singapore
• Phase I/II: NCT04480957
• Age subgroups:
• Phase I: 21-55 years
• Phase II: 21-55 years, 56-80 years
• Location: Singapore
• Type: mRNA vaccine
• Manufacturer: Arcturus Therapeutics, Duke-NUS Medical School
• VIOLIN: 5781
• VO: VO_0005164
4. AV-COVID-19
• Clinical trial ID:
• Phase I/II: NCT04386252
• Age subgroups: 18 years and older
• Location: USA
• Type: Recombinant vector vaccine
• Manufacturer: Aivita Biomedical, Inc.
• VIOLIN: 5801
• VO: VO_0005079
5. BECOV2A
• Clinical trial ID:
• Phase I/II: CTRI/2020/11/029032
• Age subgroups:
• Phase I: 18-55 years
• Phase II: 18-65 years
• Location: India
• Type: Subunit vaccine
• Manufacturer: Biological E
• VIOLIN: 5802
• VO: VO_0005081
6. CIGB-669
• Clinical trial ID:
• Phase I/II: RPCEC00000345
• Age subgroups:
Phase I: 19-54 years
Phase II: 19-80 years
• Location: Cuba
• Type: Subunit vaccine
• Manufacturer: Center for Genetic Engineering and Biotechnology (CIGB)
• VIOLIN: 5804
• VO: VO_0005083
7. COVAC
• Clinical trial ID:
• Phase I/II: NCT04702178
• Age subgroups: 18-54 years, 55-69 years, 70 years and above
• Location: Canada
• Type: Subunit vaccine
• Manufacturer: Vaccine and Infectious Disease Organization (VIDO), SEPPIC, Vaccine Formulation Institute (VFI)
• VIOLIN: 5830
• VO: VO_0005194
8. COVID-19 subunit vaccine by National Vaccine and Serum Institute of China
• Clinical trial ID:
• Phase I/II: NCT04869592
• Age subgroups:
• Phase I: 3-8 years, 9-17 years, 18-59 years, 60-69 years, 70 years and above
• Phase II: 3-8 years, 9-17 years, 18-59 years, 60-69 years, 70 years and above
• Location: China
• Type: Subunit vaccine
• Manufacturer: National Vaccine and Serum Institute, China
• VIOLIN: 5857
• VO: VO_0005248
9. COVID-eVax
• Clinical trial ID:
• Phase I/II: NCT04788459
• Age subgroups: 18-64 years, 65 years and above
• Location: Italy
• Type: DNA vaccine
• Manufacturer: Takis, Rottapharm Biotech
• VIOLIN: 5838
• VO: VO_0005230
10. COVIVAC
• Clinical trial ID:
• Phase I/II: NCT04830800
• Age subgroups:
• Phase I: 18-59 years
• Phase II: 18-75 years
• Location: Vietnam
• Type: Recombinant vector vaccine
• Manufacturer: Institute of Vaccines and Medical Biologicals, Vietnam
• VIOLIN: 5855
• VO: VO_0005246
11. DelNS1-2019-nCoV-RBD-OPT1
• Clinical trial ID:
• Phase II: ChiCTR2000039715
• Age subgroups: 18 years and above
• Location: China
• Type: Recombinant vector vaccine
• Manufacturer: Beijing Wantai Biological Pharmacy, Xiamen University
• VIOLIN: 5806
• VO: VO_0005087
12. DS-5670a
• Clinical trial ID:
• Phase I/II: NCT04821674
• Age subgroups: 20-64 years, 65-74 years
• Location: Japan
• Type: mRNA vaccine
• Manufacturer: Daiichi Sankyo Co., Ltd.
• VIOLIN: 5854
• VO: VO_0005245
13. ERUCOV-VAC
• Clinical trial ID:
• Phase II: NCT04824391
• Age subgroups: 18-64 years
• Location: Turkey
• Phase I: NCT04691947
• Age subgroups: 18-55 years
• Location: Turkey
• Type: Inactivated or "killed" vaccine
• Manufacturer: Erciyes University
• VIOLIN: 5836
• VO: VO_0005188
14. EuCorVac-19
• Clinical trial ID:
• Phase I/II: NCT04783311
• Age subgroups:
• Phase I: 19-50 years
• Phase II: 19-75 years
• Location: South Korea
• Type: Subunit vaccine
• Manufacturer: EuBiologics Co., Ltd.
• VIOLIN: 5848
• VO: VO_0005232
15. EXG-5003
• Clinical trial ID:
• Phase I/II: NCT04863131
• Age subgroups: 20-55 years
• Location: Japan
• Type: mRNA vaccine
• Manufacturer: Elixirgen Therapeutics, Inc.
• VIOLIN: 5858
• VO: VO_0005249
16. FINLAY-FR-1
• Clinical trial ID:
• Phase II: IFV/COR/11
• Age subgroups: 19-80 years
• Location: Cuba
• Phase I/II: IFV/COR/04
• Age subgroups: 19-59 years, 60-80 years
• Location: Cuba
• Type: Subunit vaccine
• Manufacturer: Instituto Finlay de Vacunas, Cuba
• VIOLIN: 5853
• VO: VO_0005244
17. GBP510
• Clinical trial ID:
• Phase I/II: NCT04742738
• Age subgroups:
• Phase I: 19-55 years
• Phase II: 19-85 years
• Location: South Korea
• Phase I/II: NCT04750343
• Age subgroups:
• Phase I: 19-55 years
• Phase II: 19-85 years
• Location: South Korea
• Type: Subunit vaccine
• Manufacturer: SK Bioscience Co., Ltd.
• VIOLIN: 5831
• VO: VO_0005197
18. GLS-5310
• Clinical trial ID:
• Phase I/II: NCT04673149
• Age subgroups:
  • Phase I: 19-50 years
  • Phase II: 19-65 years
• Location: South Korea
• Type: DNA vaccine
• Manufacturer: GeneOne Life Science, Inc.
• VIOLIN: 5807
• VO: VO_0005089
19. GX-19
• Clinical trial ID:
• Phase I/II: NCT04715997
• Age subgroups: 18-55 years
• Location: South Korea
• Phase I/II: NCT04445389
• Age subgroups: 18-50 years
• Location: South Korea
• Type: DNA vaccine
• Manufacturer: Genexine
• VIOLIN: 5788
• VO: VO_0005170
20. hAd5-COVID-19
• Clinical trial ID:
• Phase II: NCT04843722
• Age subgroups: 18-80 years
• Location: USA
• Phase II: NCT04845191
• Age subgroups: 18-80 years
• Location: USA
• Phase I: NCT04732468
• Age subgroups: 18-55 years
• Location: USA
• Phase I: NCT04591717
• Age subgroups: 18-55 years
• Location: USA
• Phase I: NCT04710303
• Age subgroups: 18-50 years
• Location: USA
• Type: Recombinant vector vaccine
• Manufacturer: ImmunityBio, Inc.; NantKwest Inc.
• VIOLIN: 5825
• VO: VO_0005189
21. IIBR-100
• Other names: BriLife
• Clinical trial ID:
• Phase I/II: NCT04608305
• Age subgroups:
• Phase I: 18-55 years
• Phase II: 18-55 years, 56-85 years
• Location: Israel
• Type: Recombinant vector vaccine
• Manufacturer: Israel Institute for Biological Research, Weizmann Institute of Science
• VIOLIN: 5799
• VO: VO_0005090
22. KBP-COVID-19
• Clinical trial ID:
• Phase I/II: NCT04473690
• Age subgroups: 18-49 years, 50-70 years
• Location: USA
• Type: Subunit vaccine
• Manufacturer: Kentucky BioProcessing
• VIOLIN: 5792
• VO: VO_0005171
23. KD-414
• Clinical trial ID:
• Phase I/II: jRCT2071200106
• Age subgroups: 20-64 years, 65 years and above
• Location: Japan
• Type: Inactivated or "killed" vaccine
• Manufacturer: KM Biologics Co., Ltd.
• VIOLIN: 5859
• VO: VO_0005250
24. LV-SMENP-DC
• Clinical trial ID:
• Phase I/II: NCT04276896
• Age subgroups: 6 months to 80 years
• Location: China
• Type: Recombinant vector vaccine
• Manufacturer: Shenzhen Geno-Immune Medical Institute
• VIOLIN: 5808
• VO: VO_0005091
25. mRNA-1273.351
• Clinical trial ID:
• Phase II: NCT04847050
• Age subgroups: 18 years and above
• Location: USA
• Phase I: NCT04785144
• Age subgroups
• Cohort 1: Previously vaccinated people 18 years and above
• Cohort 2: Unvaccinated people 18-55 years
• Location: USA
• Type: mRNA vaccine
• Manufacturer: Moderna, NIAID
• VIOLIN: 5846
• VO: VO_0005233
26. MRT5500
• Clinical trial ID:
• Phase I/II: NCT04798027
• Age subgroups: 18 years and above
• Location: USA
• Type: mRNA vaccine
• Manufacturer: Sanofi Pasteur, Translate Bio
• VIOLIN: 5850
• VO: VO_0005241
27. MVA-SARS-2-ST
• Clinical trial ID:
• Phase I/II: NCT04895449
• Age subgroups:
• Phase I: 18-64 years
• Phase II: 18 years and above
• Location: Germany
• Type: Recombinant vector vaccine
• Manufacturer: German Center for Infection Research
• VIOLIN: 5871
• VO: VO_0005262
28. MVC-COV1901
• Clinical trial ID:
• Phase II: NCT04695652
• Age subgroups: 20-64 years, 65 years and above
• Location: Taiwan, Vietnam
• Phase II: NCT04822025
• Age subgroups: 65 years and above
• Location: Taiwan
• Type: Subunit vaccine
• Manufacturer: Medigen; Dynavax
• VIOLIN: 5828
• VO: VO_0005192
29. Nanocovax
• Clinical trial ID:
• Phase I/II: NCT04683484
• Age subgroups:
• Phase I: 18-50 years
• Phase II: 12-75 years
• Location: Vietnam
• Type: Subunit vaccine
• Manufacturer: Nanogen Pharmaceutical Biotechnology
• VIOLIN: 5809
• VO: VO_0005092
30. NDV-HXP-S
• Clinical trial ID:
• Phase I/II: NCT04764422
• Age subgroups:
• Phase I: 18-59 years
• Phase II: 18-75 years
• Location: Thailand
• Type: Recombinant vector vaccine
• Manufacturer: Icahn School of Medicine at Mount Sinai, Mahidol University
• Publications:
• Sun et al. Newcastle disease virus (NDV) expressing the spike protein of SARS-CoV-2 as a live virus vaccine candidate. EBioMedicine. 2020; 62; 103132. [PubMed: 33232870].
• VIOLIN: 5841
• VO: VO_0005235
31. Razi Cov Pars
• Clinical trial ID:
• Phase II: IRCT20201214049709N2
• Age subgroups: 18-70 years
• Location: Iran
• Phase I: IRCT20201214049709N1
• Age subgroups: 18-55 years
• Location: Iran
• Type: Subunit vaccine
• Manufacturer: Razi Vaccine and Serum Research Institute
• VIOLIN: 5779
• VO: VO_0005226
32. RBD-HBsAg VLP
• Clinical trial ID:
• Phase I/II: ACTRN12620001308987
• Age subgroups:
• Phase I: 18-45 years
• Phase II: 18-79 years
• Location: Australia
• Phase I/II: ACTRN12620000817943
• Age subgroups:
• Phase I: 18-45 years
• Phase II: 18-79 years
• Location: Australia
• Type: Virus Like Particle
• Manufacturer: Serum Institute of India, Accelegen Pty
• VIOLIN: 5811
• VO: VO_0005094
33. S-268019
• Clinical trial ID:
• Phase I/II: jRCT2051200092
• Age subgroups: 20-64 years
• Location: Japan
• Type: Subunit vaccine
• Manufacturer: Shionogi
• VIOLIN: 5813
• VO: VO_0005096
34. SpikoGen
• Clinical trial ID:
• Phase II: IRCT20150303021315N23
• Age subgroups: 18 years and above
• Location: Iran
• Phase I: NCT04453852
• Age subgroups: 18-65 years
• Location: Australia
• Type: Subunit vaccine
• Manufacturer: Vaxine, CinnaGen
• VIOLIN: 5829
• VO: VO_0005193
35. V-01
• Clinical trial ID:
• Phase II: ChiCTR2100045107
• Age subgroups: 18-59 years, 60-69 years, 70 years and above
• Location: China
• Type: Subunit vaccine
• Manufacturer: Livzon Mabpharm Inc.
• VIOLIN: 5856
• VO: VO_0005247
36. VBI-2902a
• Clinical trial ID:
• Phase I/II: NCT04773665
• Age subgroups:
• Phase I: 18-54 years
• Phase II: 18-54 years, 55-65 years, 66 years and above
• Location: Canada
• Type: Virus Like Particle
• Manufacturer: VBI Vaccines Inc.
• VIOLIN: 5843
• VO: VO_0005238

Provenance: All data in Cov19VaxKB originates from manual curation of reliable resources

Note: The page was updated on May 31, 2021. We plan to update this page on a weekly or even a daily basis. Please provide us with any new information that you believe would be useful if included on the website.