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Phase II COVID-19 Vaccines

This site presents COVID-19 vaccines that are currently in Phase II clinical trials as of November 28, 2020.

Current Phase II COVID-19 vaccines include:

  1. AG0301-COVID19
    • Clinical trial ID:
      • Phase I/II: NCT04463472
        • Age subgroups: 20-65 years
        • Location: Japan
      • Phase I/II: NCT04527081
        • Age subgroups: 20-65 years
        • Location: Japan
    • Type: DNA vaccine
    • Manufacturer: AnGes, Inc.
    • VIOLIN: 5780
    • VO: VO_0005165
  2. ARCT-021
    • Other names: LUNAR-COV19
    • Clinical trial ID:
      • Phase I/II: NCT04480957
        • Age subgroups:
          • Phase I: 21-55 years
          • Phase II: 21-55 years; 56-80 years
        • Location: Singapore
    • Type: RNA vaccine
    • Manufacturer: Arcturus Therapeutics; Duke-NUS Medical School
    • VIOLIN: 5781
    • VO: VO_0005164
  3. BriLife
    • Other names: IIBR-100
    • Clinical trial ID:
      • Phase I/II: NCT04608305
        • Age subgroups:
          • Phase I: 18-55 years
          • Phase II: 18-55 years; 56-85 years
        • Location: Israel
    • Type: Recombinant vector vaccine
    • Manufacturer: Israel Institute for Biological Research; Weizmann Institute of Science
  4. COVID-19 inactivated virus vaccine by Beijing Minhai Biotechnology
    • Clinical trial ID:
    • Type: Inactivated or "killed" vaccine
    • Manufacturer: Beijing Minhai Biotechnology Co., Ltd.
  5. COVID-19 inactivated virus vaccine by Chinese Academy of Medical Sciences
    • Clinical trial ID:
      • Phase I/II: NCT04412538
        • Age subgroups: 18-59 years
        • Location: China
      • Phase I/II: NCT04470609
        • Age subgroups: 60 years and above
        • Location: China
    • Type: Inactivated or “killed” vaccine
    • Manufacturer: Institute of Medical Biology, Chinese Academy of Medical Sciences
    • VIOLIN: 5785
    • VO: VO_0005167
  6. COVID-19 protein subunit vaccine by Sanofi and GSK
    • Clinical trial ID:
      • Phase I/II: NCT04537208
        • Age subgroups: 18-49 years; 50 years and above
        • Location: USA
    • Type: Subunit vaccine
    • Manufacturer: Sanofi Pasteur; GSK
  7. CVnCoV
    • Clinical trial ID:
      • Phase II: NCT04515147
        • Age subgroups: 18-60 years; 61 years and above
        • Location: Panama, Peru
    • Type: RNA vaccine
    • Manufacturer: Curevac
    • VIOLIN: 5786
    • VO: VO_0005168
  8. DelNS1-2019-nCoV-RBD-OPT1
    • Clinical trial ID:
    • Type: Recombinant vector vaccine
    • Manufacturer: Beijing Wantai Biological Pharmacy; Xiamen University
  9. EpiVacCorona
    • Clinical trial ID:
      • Phase I/II: NCT04527575
        • Age subgroups:
          • Phase I: 18-30 years
          • Phase II: 18-60 years
        • Location: Russia
    • Type: Peptide vaccine
    • Manufacturer: FBRI State Research Center of Virology and Biotechnology
  10. GX-19
    • Clinical trial ID:
      • Phase I/II: NCT04445389
        • Age subgroups: 18-50 years
        • Location: South Korea
    • Type: DNA vaccine
    • Manufacturer: Genexine
    • VIOLIN: 5788
    • VO: VO_0005170
  11. INO-4800
    • Clinical trial ID:
      • Phase I/II: NCT04447781
        • Age subgroups:
          • Phase I: 19-64 years
          • Phase II: 19-50 years; 51-64 years
        • Location: South Korea
    • Type: DNA vaccine
    • Manufacturer: Inovio Pharmaceuticals
    • Publications:
      • Smith et al. Immunogenicity of a DNA vaccine candidate for COVID-19. Nat Commun. 2020; 11(1); 2601. [PubMed: 32433465].
    • VIOLIN: 5793
    • VO: VO_0005172
  12. KBP-COVID-19
    • Clinical trial ID:
      • Phase I/II: NCT04473690
        • Age subgroups: 18-49 years; 50-70 years
    • Type: Subunit vaccine
    • Manufacturer: Kentucky BioProcessing
    • VIOLIN: 5792
    • VO: VO_0005171
  13. QazCovid-in
    • Clinical trial ID:
      • Phase II: NCT04530357
        • Age subgroups:
          • Phase I: 18-50 years
          • Phase II: 18 years and above
        • Location: Kazakhstan
    • Type: Inactivated or "killed" vaccine
    • Manufacturer: Research Institute for Biological Safety Problems; National Scientific Center for Phthisiopulmonology of the Republic of Kazakhstan
  14. RBD-CuMVTT
    • Clinical trial ID:
      • Phase II: NCT04466085
        • Age subgroups: 18-59 years
        • Location: China
    • Type: Virus Like Particle
    • Manufacturer: Anhui Zhifei Longcom Biopharmaceutical; Institute of Microbiology, Chinese Academy of Sciences
    • Publications:
      • Dai et al. A Universal Design of Betacoronavirus Vaccines against COVID-19, MERS, and SARS. Cell. 2020; 182(3); 722-733. [PubMed: 32645327].
    • VIOLIN: 5764
    • VO: VO_0005142
  15. RBD-HBsAg VLP
    • Clinical trial ID:
      • Phase I/II: ACTRN12620000817943
        • Age subgroups:
          • Phase I: 18-45 years
          • Phase II: 18-79 years
        • Location: Australia
    • Type: Virus Like Particle
    • Manufacturer: Serum Institute of India
  16. V591
    • Clinical trial ID:
      • Phase I/II: NCT04498247
        • Age subgroups: 18-55 years; 56 years and above
        • Location: USA, Austria, Belgium
    • Type: Recombinant vector vaccine
    • Manufacturer: Merck
  17. ZyCoV-D
    • Clinical trial ID:
      • Phase I/II: CTRI/2020/07/026352
        • Age subgroups:
          • Phase I: 18-45 years
          • Phase II: 18-79 years
        • Location: Australia
    • Type: DNA vaccine
    • Manufacturer: Zydus Cadila
    • VIOLIN: 5778
    • VO: VO_0005162

Provenance: All data in Cov19VaxKB originates from manual curation of reliable resources

Note: The page was updated on November 28, 2020. We plan to update this page on a weekly or even a daily basis. Please provide us with any new information that you believe would be useful if included on the website.