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Phase II COVID-19 Vaccines

This site presents an alphabetically-ordered list of COVID-19 vaccines that are currently in Phase II clinical trials as of January 7, 2022.

Current Phase II COVID-19 vaccines include:

Contents:

1. 202-CoV
2. AAV5-RBD-S
3. ABNCoV2
4. AdCLD-CoV19
5. AdimrSC-2f
6. AG0302-COVID19
7. AKS-452
8. AmitisGen
9. ARCT-021
10. ARCT-165
11. AV-COVID-19
12. CIGB-669
13. COH04S1
14. COVAC
15. COVID-19 mRNA vaccine by Shanghai East Hospital and Stemirna Therapeutics
16. COVID-19 subunit vaccine by HIPRA
17. COVID-19 subunit vaccine by National Vaccine and Serum Institute of China
18. COVID-19 subunit vaccine by PT Bio Farma
19. COVID-19 VLP vaccine by the Scientific and Technological Research Council of Turkey
20. COVID-eVax
21. COVIVAC
22. DS-5670a
23. EuCorVac-19
24. EXG-5003
25. FINLAY-FR-1
26. GLS-5310
27. hAd5-COVID-19
28. IMP CoVac-1
29. KBP-COVID-19
30. Koçak-19 Inaktif Adjuvanlı COVID-19 Vaccine
31. LV-SMENP-DC
32. mRNA-1283
33. MRT5500
34. MVA-SARS-2-ST
35. NDV-HXP-S
36. QazCoVac-P
37. RBD-HBsAg VLP
38. S-268019
39. SCB-2020S
40. SII B.1.351
41. SII B.1.617.2
42. SII Bivalent
43. VB10.2129
44. VB10.2210
45. VBI-2902a
46. VXA-CoV2-1

1. 202-CoV
• Clinical trial ID:
• Phase II: NCT04990544
• Age subgroups: 18-59 years; 60 years and above
• Location: China
• Phase I: NCT04982068
• Age subgroups: 18-59 years; 60 years and above
• Location: China
• Type: Subunit vaccine
• Manufacturer: Shanghai Zerun Biotechnology, Walvax Biotechnology, CEPI
• VIOLIN: 5835
• VO: VO_0005320
2. AAV5-RBD-S
• Clinical trial ID:
• Phase I/II: NCT05037188
• Age subgroups: 18-60 years
• Location: Russia
• Type: Recombinant vector vaccine
• Manufacturer: Biocad
• VIOLIN: 5889
• VO: VO_0005336
3. ABNCoV2
• Clinical trial ID:
• Phase II: NCT05077267
• Age subgroups: 18 years and above
• Location: Germany
• Phase I: NCT04839146
• Age subgroups: 18-55 years
• Location: Netherlands
• Type: Virus like particle vaccine
• Manufacturer: AdaptVac, Bavarian Nordic, and Radboud University
• VIOLIN: 5865
• VO: VO_0005255
4. AdCLD-CoV19
• Clinical trial ID:
• Phase I/II: NCT04666012
• Age subgroups: 19-64 years
• Location: South Korea
• Type: Recombinant vector vaccine
• Manufacturer: Cellid Co., Ltd.
• VIOLIN: 5800
• VO: VO_0004996
5. AdimrSC-2f
• Clinical trial ID:
• Phase I/II: NCT05104489
• Age subgroups: 18-60 years
• Location: Indonesia
• Phase I: NCT04522089
• Age subgroups: 20-60 years
• Location: Taiwan
• Type: Subunit vaccine
• Manufacturer: Adimmune Corporation
• VO: VO_0005173
6. AG0302-COVID19
• Clinical trial ID:
• Phase I/II: NCT04463472
• Age subgroups: 20-65 years
• Location: Japan
• Type: DNA vaccine
• Manufacturer: AnGes, Inc.
• VIOLIN: 5780
• VO: VO_0005165
7. AKS-452
• Clinical trial ID:
• Phase II: NCT05124483
• Age subgroups: 18-85 years
• Location: Netherlands
• Phase I/II: NCT04681092
• Age subgroups: 18-55 years
• Location: Netherlands
• Type: Subunit vaccine
• Manufacturer: University Medical Center Groningen, Akston Biosciences Inc.
• VIOLIN: 5834
• VO: VO_0004999
8. AmitisGen
• Clinical trial ID:
• Phase II: IRCT20210620051639N2
• Age subgroups: 18-40 years
• Location: Iran
• Phase I: IRCT20210620051639N1
• Age subgroups: 18-50 years
• Location: Iran
• Type: Subunit vaccine
• Manufacturer: Bagheiat-allah University of Medical Sciences
• VIOLIN: 5877
• VO: VO_0005316
9. ARCT-021
• Other names: LUNAR-COV19
• Clinical trial ID:
• Phase I/II: NCT05037097
• Age subgroups: 21-65 years
• Location: USA, Singapore
• Phase II: NCT04728347
• Age subgroups: 18-55 years (21-55 years in Singapore), 56 years and above
• Location: USA, Singapore
• Phase II: NCT04728347
• Age subgroups: 21-80 years
• Location: Singapore
• Phase I/II: NCT04480957
• Age subgroups:
• Phase I: 21-55 years
• Phase II: 21-55 years, 56-80 years
• Location: Singapore
• Type: mRNA vaccine
• Manufacturer: Arcturus Therapeutics, Duke-NUS Medical School
• VIOLIN: 5781
• VO: VO_0005164
10. ARCT-165
• Clinical trial ID:
• Phase I/II: NCT05037097
• Age subgroups: 21-65 years
• Location: USA, Singapore
• Type: RNA vaccine
• Manufacturer: Arcturus Therapeutics, Inc.
• VIOLIN: 5888
• VO: VO_0005332
11. AV-COVID-19
• Clinical trial ID:
• Phase II: NCT05007496
• Age subgroups: 18 years and above
• Location: Indonesia
• Phase I/II: NCT04386252
• Age subgroups: 18 years and above
• Location: USA
• Type: Recombinant vector vaccine
• Manufacturer: Aivita Biomedical, Inc.
• VIOLIN: 5801
• VO: VO_0005079
12. CIGB-669
• Clinical trial ID:
• Phase I/II: RPCEC00000345
• Age subgroups:
Phase I: 19-54 years
Phase II: 19-80 years
• Location: Cuba
• Type: Subunit vaccine
• Manufacturer: Center for Genetic Engineering and Biotechnology (CIGB)
• VIOLIN: 5804
• VO: VO_0005083
13. COH04S1
• Clinical trial ID:
• Phase II: NCT04977024
• Age subgroups: 18 years and above
• Location: USA
• Phase I: NCT04639466
• Age subgroups: 18-55 years
• Location: USA
• Type: Recombinant vector vaccine
• Manufacturer: City of Hope Medical Center
• Publications
• Chiuppesi et al. Development of a multi-antigenic SARS-CoV-2 vaccine candidate using a synthetic poxvirus platform. Nat Commun. 2020; 11(1); 6121. [PubMed: 33257686].
• VIOLIN: 5819
• VO: VO_0005176
14. COVAC
• Clinical trial ID:
• Phase I/II: NCT04702178
• Age subgroups: 18-54 years, 55-69 years, 70 years and above
• Location: Canada
• Type: Subunit vaccine
• Manufacturer: Vaccine and Infectious Disease Organization (VIDO), SEPPIC, Vaccine Formulation Institute (VFI)
• VIOLIN: 5830
• VO: VO_0005194
15. COVID-19 mRNA vaccine by Shanghai East Hospital and Stemirna Therapeutics
• Clinical trial ID:
• Phase I/II: NCT05144139
• Age subgroups: 18-60 years
• Location: China
• Phase I: ChiCTR2100045984
• Age subgroups: 18 years and above
• Location: China
• Phase not reported: NCT04944381
• Age subgroups: 18 years and above
• Location: Unknown
• Type: mRNA vaccine
• Manufacturer: Shanghai East Hospital and Stemirna Therapeutics
• VIOLIN: 5869
• VO: VO_0005260
16. COVID-19 subunit vaccine by HIPRA
• Clinical trial ID:
• Phase II: EUCTR2021-005226-26-ES
• Age subgroups: 18-64 years, 65 years and above
• Location: Spain
• Phase I/II: NCT05007509
• Age subgroups: 18-39 years
• Location: Spain
• Type: Subunit vaccine
• Manufacturer: Laboratorios Hipra, S.A.
• VIOLIN: 5883
• VO: VO_0005321
17. COVID-19 subunit vaccine by National Vaccine and Serum Institute of China
• Clinical trial ID:
• Phase I/II: NCT05069129
• Age subgroups: 18 years and above
• Location: UAE
• Phase I/II: NCT04869592
• Age subgroups:
• Phase I: 3-8 years, 9-17 years, 18-59 years, 60-69 years, 70 years and above
• Phase II: 3-8 years, 9-17 years, 18-59 years, 60-69 years, 70 years and above
• Location: China
• Type: Subunit vaccine
• Manufacturer: National Vaccine and Serum Institute, China
• VIOLIN: 5857
• VO: VO_0005248
18. COVID-19 subunit vaccine by PT Bio Farma
• Clinical trial ID:
• Phase I/II: NCT05067894
• Age subgroups: 18-59 years, 60 years and above
• Location: Indonesia
• Type: Subunit vaccine
• Manufacturer: PT Bio Farma
• VIOLIN: 5895
• VO: VO_0005343
19. COVID-19 VLP vaccine by the Scientific and Technological Research Council of Turkey
• Clinical trial ID:
• Phase II: NCT04962893
• Age subgroups: 18-59 years
• Location: Turkey
• Phase I: NCT04818281
• Age subgroups: 18-59 years
• Location: Turkey
• Type: Virus like particle vaccine
• Manufacturer: The Scientific and Technological Research Council of Turkey
• VIOLIN: 5862
• VO: VO_0005251
20. COVID-eVax
• Clinical trial ID:
• Phase I/II: NCT04788459
• Age subgroups: 18-64 years, 65 years and above
• Location: Italy
• Type: DNA vaccine
• Manufacturer: Takis, Rottapharm Biotech
• VIOLIN: 5838
• VO: VO_0005230
21. COVIVAC
• Clinical trial ID:
• Phase I/II: NCT04830800
• Age subgroups:
• Phase I: 18-59 years
• Phase II: 18-75 years
• Location: Vietnam
• Type: Recombinant vector vaccine
• Manufacturer: Institute of Vaccines and Medical Biologicals, Vietnam
• VIOLIN: 5855
• VO: VO_0005246
22. DS-5670a
• Clinical trial ID:
• Phase I/II: NCT04821674
• Age subgroups: 20-64 years, 65-74 years
• Location: Japan
• Type: mRNA vaccine
• Manufacturer: Daiichi Sankyo Co., Ltd.
• VIOLIN: 5854
• VO: VO_0005245
23. EuCorVac-19
• Clinical trial ID:
• Phase I/II: NCT04783311
• Age subgroups:
• Phase I: 19-50 years
• Phase II: 19-75 years
• Location: South Korea
• Type: Subunit vaccine
• Manufacturer: EuBiologics Co., Ltd.
• VIOLIN: 5848
• VO: VO_0005232
24. EXG-5003
• Clinical trial ID:
• Phase I/II: NCT04863131
• Age subgroups: 20-55 years
• Location: Japan
• Type: mRNA vaccine
• Manufacturer: Elixirgen Therapeutics, Inc.
• VIOLIN: 5858
• VO: VO_0005249
25. FINLAY-FR-1
• Clinical trial ID:
• Phase II: IFV/COR/11
• Age subgroups: 19-80 years
• Location: Cuba
• Phase I/II: IFV/COR/04
• Age subgroups: 19-59 years, 60-80 years
• Location: Cuba
• Type: Subunit vaccine
• Manufacturer: Instituto Finlay de Vacunas, Cuba
• VIOLIN: 5853
• VO: VO_0005244
26. GLS-5310
• Clinical trial ID:
• Phase I/II: NCT04673149
• Age subgroups:
  • Phase I: 19-50 years
  • Phase II: 19-65 years
• Location: South Korea
• Type: DNA vaccine
• Manufacturer: GeneOne Life Science, Inc.
• VIOLIN: 5807
• VO: VO_0005089
27. hAd5-COVID-19
• Clinical trial ID:
• Phase II: NCT04843722
• Age subgroups: 18-80 years
• Location: USA
• Phase II: NCT04845191
• Age subgroups: 18-80 years
• Location: USA
• Phase I: NCT04732468
• Age subgroups: 18-55 years
• Location: USA
• Phase I: NCT04591717
• Age subgroups: 18-55 years
• Location: USA
• Phase I: NCT04710303
• Age subgroups: 18-50 years
• Location: USA
• Type: Recombinant vector vaccine
• Manufacturer: ImmunityBio, Inc.; NantKwest Inc.
• VIOLIN: 5825
• VO: VO_0005189
28. IMP CoVac-1
• Clinical trial ID:
• Phase I/II: NCT04954469
• Age subgroups: 18 years and above
• Location: Germany
• Phase I: NCT04546841
• Age subgroups: 18-55 years, 56-74 years, 75 years and above
• Location: Germany
• Type: Subunit vaccine
• Manufacturer: University Hospital Tuebingen
• VIOLIN: 5826
• VO: VO_0005190
29. KBP-COVID-19
• Clinical trial ID:
• Phase I/II: NCT04473690
• Age subgroups: 18-49 years, 50-70 years
• Location: USA
• Type: Subunit vaccine
• Manufacturer: Kentucky BioProcessing
• VIOLIN: 5792
• VO: VO_0005171
30. Koçak-19 Inaktif Adjuvanlı COVID-19 Vaccine
• Clinical trial ID:
• Phase II: NCT05035238
• Age subgroups: 18-64 years
• Location: Turkey
• Phase I: NCT04838080
• Age subgroups: 18-55 years
• Location: Turkey
• Type: Inactivated or "killed" vaccine
• Manufacturer: Kocak Farma
• VIOLIN: 5860
• VO: VO_0005253
31. LV-SMENP-DC
• Clinical trial ID:
• Phase I/II: NCT04276896
• Age subgroups: 6 months to 80 years
• Location: China
• Type: Recombinant vector vaccine
• Manufacturer: Shenzhen Geno-Immune Medical Institute
• VIOLIN: 5808
• VO: VO_0005091
32. mRNA-1283
• Clinical trial ID:
• Phase II: NCT05137236
• Age subgroups: People 18 years and above who have received their second dose of mRNA-1273 vaccine at least 6 months prior to screening and enrollment
• Location: USA
• Phase I: NCT04813796
• Age subgroups: Unvaccinated people 18-55 years
• Location: USA
• Type: mRNA vaccine
• Manufacturer: Moderna, NIAID
• VIOLIN: 5868
• VO: VO_0005185
33. MRT5500
• Clinical trial ID:
• Phase I/II: NCT04798027
• Age subgroups: 18 years and above
• Location: USA
• Type: mRNA vaccine
• Manufacturer: Sanofi Pasteur, Translate Bio
• VIOLIN: 5850
• VO: VO_0005241
34. MVA-SARS-2-ST
• Clinical trial ID:
• Phase I/II: NCT04895449
• Age subgroups:
• Phase I: 18-64 years
• Phase II: 18 years and above
• Location: Germany
• Type: Recombinant vector vaccine
• Manufacturer: German Center for Infection Research
• VIOLIN: 5871
• VO: VO_0005262
35. NDV-HXP-S
• Clinical trial ID:
• Phase I/II: NCT04764422
• Age subgroups:
• Phase I: 18-59 years
• Phase II: 18-75 years
• Location: Thailand
• Type: Recombinant vector vaccine
• Manufacturer: Icahn School of Medicine at Mount Sinai, Mahidol University
• Publications:
• Sun et al. Newcastle disease virus (NDV) expressing the spike protein of SARS-CoV-2 as a live virus vaccine candidate. EBioMedicine. 2020; 62; 103132. [PubMed: 33232870].
• VIOLIN: 5841
• VO: VO_0005235
36. QazCoVac-P
• Clinical trial ID:
• Phase I/II: NCT04930003
• Age subgroups:
• Phase I: 18-50 years
• Phase II: 18 years and above
• Location: Kazakhstan
• Type: Subunit vaccine
• Manufacturer: Research Institute for Biological Safety Problems
• VIOLIN: 5874
• VO: VO_0005273
37. RBD-HBsAg VLP
• Clinical trial ID:
• Phase I/II: ACTRN12620001308987
• Age subgroups:
• Phase I: 18-45 years
• Phase II: 18-79 years
• Location: Australia
• Phase I/II: ACTRN12620000817943
• Age subgroups:
• Phase I: 18-45 years
• Phase II: 18-79 years
• Location: Australia
• Type: Virus Like Particle
• Manufacturer: Serum Institute of India, Accelegen Pty
• VIOLIN: 5811
• VO: VO_0005094
38. S-268019
• Clinical trial ID:
• Phase I/II: jRCT2051200092
• Age subgroups: 20-64 years
• Location: Japan
• Type: Subunit vaccine
• Manufacturer: Shionogi
• VIOLIN: 5813
• VO: VO_0005096
39. SCB-2020S
• Clinical trial ID:
• Phase II: NCT04950751
• Age subgroups: 18 years and above
• Location: Unknown
• Type: Subunit vaccine
• Manufacturer: Clover Biopharmaceuticals AUS Pty Ltd
• VIOLIN: 5879
• VO: VO_0005315
40. SII B.1.351
• Clinical trial ID:
• Phase I/II: NCT05029856
• Age subgroups: 18-64 years
• Location: Australia
• Type: Subunit vaccine
• Manufacturer: Novavax
• VIOLIN: 5885
• VO: VO_0005333
41. SII B.1.617.2
• Clinical trial ID:
• Phase I/II: NCT05029856
• Age subgroups: 18-64 years
• Location: Australia
• Type: Subunit vaccine
• Manufacturer: Novavax
• VIOLIN: 5886
• VO: VO_0005335
42. SII Bivalent
• Clinical trial ID:
• Phase I/II: NCT05029856
• Age subgroups: 18-64 years
• Location: Australia
• Type: Subunit vaccine
• Manufacturer: Novavax
• VIOLIN: 5887
• VO: VO_0005334
43. VB10.2129
• Clinical trial ID:
• Phase I/II: NCT05069623
• Age subgroups: 18-60 years
• Location: Norway
• Type: DNA vaccine
• Manufacturer: Vaccibody AS
• VIOLIN: 5893
• VO: VO_0005340
44. VB10.2210
• Clinical trial ID:
• Phase I/II: NCT05069623
• Age subgroups: 18-60 years
• Location: Norway
• Type: DNA vaccine
• Manufacturer: Vaccibody AS
• VIOLIN: 5894
• VO: VO_0005341
45. VBI-2902a
• Clinical trial ID:
• Phase I/II: NCT04773665
• Age subgroups:
• Phase I: 18-54 years
• Phase II: 18-54 years, 55-65 years, 66 years and above
• Location: Canada
• Type: Virus Like Particle
• Manufacturer: VBI Vaccines Inc.
• VIOLIN: 5843
• VO: VO_0005238
46. VXA-CoV2-1
• Clinical trial ID:
• Phase II: NCT05067933
• Age subgroups: 18-75 years
• Location: USA
• Phase I: NCT04563702
• Age subgroups: 18-54 years
• Location: USA
• Type: Recombinant vector vaccine
• Manufacturer: Vaxart
• VIOLIN: 5832
• VO: VO_0005196

Provenance: All data in Cov19VaxKB originates from manual curation of reliable resources

Note: The page was updated on January 7, 2022. We plan to update this page on a weekly or even a daily basis. Please provide us with any new information that you believe would be useful if included on the website.