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Phase II COVID-19 Vaccines

This site presents an alphabetically-ordered list of COVID-19 vaccines that are currently in Phase II clinical trials as of January 7, 2022.

Current Phase II COVID-19 vaccines include:

Contents:

  1. 202-CoV
  2. AAV5-RBD-S
  3. ABNCoV2
  4. AdCLD-CoV19
  5. AdimrSC-2f
  6. AG0302-COVID19
  7. AKS-452
  8. AmitisGen
  9. ARCT-021
  10. ARCT-165
  11. AV-COVID-19
  12. CIGB-669
  13. COH04S1
  14. COVAC
  15. COVID-19 mRNA vaccine by Shanghai East Hospital and Stemirna Therapeutics
  16. COVID-19 subunit vaccine by HIPRA
  17. COVID-19 subunit vaccine by National Vaccine and Serum Institute of China
  18. COVID-19 subunit vaccine by PT Bio Farma
  19. COVID-19 VLP vaccine by the Scientific and Technological Research Council of Turkey
  20. COVID-eVax
  21. COVIVAC
  22. DS-5670a
  23. EuCorVac-19
  24. EXG-5003
  25. FINLAY-FR-1
  26. GLS-5310
  27. hAd5-COVID-19
  28. IMP CoVac-1
  29. KBP-COVID-19
  30. Koçak-19 Inaktif Adjuvanlı COVID-19 Vaccine
  31. LV-SMENP-DC
  32. mRNA-1283
  33. MRT5500
  34. MVA-SARS-2-ST
  35. NDV-HXP-S
  36. QazCoVac-P
  37. RBD-HBsAg VLP
  38. S-268019
  39. SCB-2020S
  40. SII B.1.351
  41. SII B.1.617.2
  42. SII Bivalent
  43. VB10.2129
  44. VB10.2210
  45. VBI-2902a
  46. VXA-CoV2-1


  1. 202-CoV
    • Clinical trial ID:
      • Phase II: NCT04990544
        • Age subgroups: 18-59 years; 60 years and above
        • Location: China
      • Phase I: NCT04982068
        • Age subgroups: 18-59 years; 60 years and above
        • Location: China
    • Type: Subunit vaccine
    • Manufacturer: Shanghai Zerun Biotechnology, Walvax Biotechnology, CEPI
    • VIOLIN: 5835
    • VO: VO_0005320
  2. AAV5-RBD-S
    • Clinical trial ID:
      • Phase I/II: NCT05037188
        • Age subgroups: 18-60 years
        • Location: Russia
    • Type: Recombinant vector vaccine
    • Manufacturer: Biocad
    • VIOLIN: 5889
    • VO: VO_0005336
  3. ABNCoV2
    • Clinical trial ID:
      • Phase II: NCT05077267
        • Age subgroups: 18 years and above
        • Location: Germany
      • Phase I: NCT04839146
        • Age subgroups: 18-55 years
        • Location: Netherlands
    • Type: Virus like particle vaccine
    • Manufacturer: AdaptVac, Bavarian Nordic, and Radboud University
    • VIOLIN: 5865
    • VO: VO_0005255
  4. AdCLD-CoV19
    • Clinical trial ID:
      • Phase I/II: NCT04666012
        • Age subgroups: 19-64 years
        • Location: South Korea
    • Type: Recombinant vector vaccine
    • Manufacturer: Cellid Co., Ltd.
    • VIOLIN: 5800
    • VO: VO_0004996
  5. AdimrSC-2f
    • Clinical trial ID:
      • Phase I/II: NCT05104489
        • Age subgroups: 18-60 years
        • Location: Indonesia
      • Phase I: NCT04522089
        • Age subgroups: 20-60 years
        • Location: Taiwan
    • Type: Subunit vaccine
    • Manufacturer: Adimmune Corporation
    • VO: VO_0005173
  6. AG0302-COVID19
    • Clinical trial ID:
      • Phase I/II: NCT04463472
        • Age subgroups: 20-65 years
        • Location: Japan
    • Type: DNA vaccine
    • Manufacturer: AnGes, Inc.
    • VIOLIN: 5780
    • VO: VO_0005165
  7. AKS-452
    • Clinical trial ID:
      • Phase II: NCT05124483
        • Age subgroups: 18-85 years
        • Location: Netherlands
      • Phase I/II: NCT04681092
        • Age subgroups: 18-55 years
        • Location: Netherlands
    • Type: Subunit vaccine
    • Manufacturer: University Medical Center Groningen, Akston Biosciences Inc.
    • VIOLIN: 5834
    • VO: VO_0004999
  8. AmitisGen
    • Clinical trial ID:
    • Type: Subunit vaccine
    • Manufacturer: Bagheiat-allah University of Medical Sciences
    • VIOLIN: 5877
    • VO: VO_0005316
  9. ARCT-021
    • Other names: LUNAR-COV19
    • Clinical trial ID:
      • Phase I/II: NCT05037097
        • Age subgroups: 21-65 years
        • Location: USA, Singapore
      • Phase II: NCT04728347
        • Age subgroups: 18-55 years (21-55 years in Singapore), 56 years and above
        • Location: USA, Singapore
      • Phase II: NCT04728347
        • Age subgroups: 21-80 years
        • Location: Singapore
      • Phase I/II: NCT04480957
        • Age subgroups:
          • Phase I: 21-55 years
          • Phase II: 21-55 years, 56-80 years
        • Location: Singapore
    • Type: mRNA vaccine
    • Manufacturer: Arcturus Therapeutics, Duke-NUS Medical School
    • VIOLIN: 5781
    • VO: VO_0005164
  10. ARCT-165
    • Clinical trial ID:
      • Phase I/II: NCT05037097
        • Age subgroups: 21-65 years
        • Location: USA, Singapore
    • Type: RNA vaccine
    • Manufacturer: Arcturus Therapeutics, Inc.
    • VIOLIN: 5888
    • VO: VO_0005332
  11. AV-COVID-19
    • Clinical trial ID:
      • Phase II: NCT05007496
        • Age subgroups: 18 years and above
        • Location: Indonesia
      • Phase I/II: NCT04386252
        • Age subgroups: 18 years and above
        • Location: USA
    • Type: Recombinant vector vaccine
    • Manufacturer: Aivita Biomedical, Inc.
    • VIOLIN: 5801
    • VO: VO_0005079
  12. CIGB-669
    • Clinical trial ID:
      • Phase I/II: RPCEC00000345
        • Age subgroups:
          • Phase I: 19-54 years
            Phase II: 19-80 years
        • Location: Cuba
    • Type: Subunit vaccine
    • Manufacturer: Center for Genetic Engineering and Biotechnology (CIGB)
    • VIOLIN: 5804
    • VO: VO_0005083
  13. COH04S1
    • Clinical trial ID:
      • Phase II: NCT04977024
        • Age subgroups: 18 years and above
        • Location: USA
      • Phase I: NCT04639466
        • Age subgroups: 18-55 years
        • Location: USA
    • Type: Recombinant vector vaccine
    • Manufacturer: City of Hope Medical Center
    • Publications
      • Chiuppesi et al. Development of a multi-antigenic SARS-CoV-2 vaccine candidate using a synthetic poxvirus platform. Nat Commun. 2020; 11(1); 6121. [PubMed: 33257686].
    • VIOLIN: 5819
    • VO: VO_0005176
  14. COVAC
    • Clinical trial ID:
      • Phase I/II: NCT04702178
        • Age subgroups: 18-54 years, 55-69 years, 70 years and above
        • Location: Canada
    • Type: Subunit vaccine
    • Manufacturer: Vaccine and Infectious Disease Organization (VIDO), SEPPIC, Vaccine Formulation Institute (VFI)
    • VIOLIN: 5830
    • VO: VO_0005194
  15. COVID-19 mRNA vaccine by Shanghai East Hospital and Stemirna Therapeutics
    • Clinical trial ID:
      • Phase I/II: NCT05144139
        • Age subgroups: 18-60 years
        • Location: China
      • Phase I: ChiCTR2100045984
        • Age subgroups: 18 years and above
        • Location: China
      • Phase not reported: NCT04944381
        • Age subgroups: 18 years and above
        • Location: Unknown
    • Type: mRNA vaccine
    • Manufacturer: Shanghai East Hospital and Stemirna Therapeutics
    • VIOLIN: 5869
    • VO: VO_0005260
  16. COVID-19 subunit vaccine by HIPRA
    • Clinical trial ID:
    • Type: Subunit vaccine
    • Manufacturer: Laboratorios Hipra, S.A.
    • VIOLIN: 5883
    • VO: VO_0005321
  17. COVID-19 subunit vaccine by National Vaccine and Serum Institute of China
    • Clinical trial ID:
      • Phase I/II: NCT05069129
        • Age subgroups: 18 years and above
        • Location: UAE
      • Phase I/II: NCT04869592
        • Age subgroups:
          • Phase I: 3-8 years, 9-17 years, 18-59 years, 60-69 years, 70 years and above
          • Phase II: 3-8 years, 9-17 years, 18-59 years, 60-69 years, 70 years and above
        • Location: China
    • Type: Subunit vaccine
    • Manufacturer: National Vaccine and Serum Institute, China
    • VIOLIN: 5857
    • VO: VO_0005248
  18. COVID-19 subunit vaccine by PT Bio Farma
    • Clinical trial ID:
      • Phase I/II: NCT05067894
        • Age subgroups: 18-59 years, 60 years and above
        • Location: Indonesia
    • Type: Subunit vaccine
    • Manufacturer: PT Bio Farma
    • VIOLIN: 5895
    • VO: VO_0005343
  19. COVID-19 VLP vaccine by the Scientific and Technological Research Council of Turkey
    • Clinical trial ID:
      • Phase II: NCT04962893
        • Age subgroups: 18-59 years
        • Location: Turkey
      • Phase I: NCT04818281
        • Age subgroups: 18-59 years
        • Location: Turkey
    • Type: Virus like particle vaccine
    • Manufacturer: The Scientific and Technological Research Council of Turkey
    • VIOLIN: 5862
    • VO: VO_0005251
  20. COVID-eVax
    • Clinical trial ID:
      • Phase I/II: NCT04788459
        • Age subgroups: 18-64 years, 65 years and above
        • Location: Italy
    • Type: DNA vaccine
    • Manufacturer: Takis, Rottapharm Biotech
    • VIOLIN: 5838
    • VO: VO_0005230
  21. COVIVAC
    • Clinical trial ID:
      • Phase I/II: NCT04830800
        • Age subgroups:
          • Phase I: 18-59 years
          • Phase II: 18-75 years
        • Location: Vietnam
    • Type: Recombinant vector vaccine
    • Manufacturer: Institute of Vaccines and Medical Biologicals, Vietnam
    • VIOLIN: 5855
    • VO: VO_0005246
  22. DS-5670a
    • Clinical trial ID:
      • Phase I/II: NCT04821674
        • Age subgroups: 20-64 years, 65-74 years
        • Location: Japan
    • Type: mRNA vaccine
    • Manufacturer: Daiichi Sankyo Co., Ltd.
    • VIOLIN: 5854
    • VO: VO_0005245
  23. EuCorVac-19
    • Clinical trial ID:
      • Phase I/II: NCT04783311
        • Age subgroups:
          • Phase I: 19-50 years
          • Phase II: 19-75 years
        • Location: South Korea
    • Type: Subunit vaccine
    • Manufacturer: EuBiologics Co., Ltd.
    • VIOLIN: 5848
    • VO: VO_0005232
  24. EXG-5003
    • Clinical trial ID:
      • Phase I/II: NCT04863131
        • Age subgroups: 20-55 years
        • Location: Japan
    • Type: mRNA vaccine
    • Manufacturer: Elixirgen Therapeutics, Inc.
    • VIOLIN: 5858
    • VO: VO_0005249
  25. FINLAY-FR-1
    • Clinical trial ID:
      • Phase II: IFV/COR/11
        • Age subgroups: 19-80 years
        • Location: Cuba
      • Phase I/II: IFV/COR/04
        • Age subgroups: 19-59 years, 60-80 years
        • Location: Cuba
    • Type: Subunit vaccine
    • Manufacturer: Instituto Finlay de Vacunas, Cuba
    • VIOLIN: 5853
    • VO: VO_0005244
  26. GLS-5310
    • Clinical trial ID:
      • Phase I/II: NCT04673149
        • Age subgroups:
          • Phase I: 19-50 years
          • Phase II: 19-65 years
        • Location: South Korea
    • Type: DNA vaccine
    • Manufacturer: GeneOne Life Science, Inc.
    • VIOLIN: 5807
    • VO: VO_0005089
  27. hAd5-COVID-19
    • Clinical trial ID:
      • Phase II: NCT04843722
        • Age subgroups: 18-80 years
        • Location: USA
      • Phase II: NCT04845191
        • Age subgroups: 18-80 years
        • Location: USA
      • Phase I: NCT04732468
        • Age subgroups: 18-55 years
        • Location: USA
      • Phase I: NCT04591717
        • Age subgroups: 18-55 years
        • Location: USA
      • Phase I: NCT04710303
        • Age subgroups: 18-50 years
        • Location: USA
    • Type: Recombinant vector vaccine
    • Manufacturer: ImmunityBio, Inc.; NantKwest Inc.
    • VIOLIN: 5825
    • VO: VO_0005189
  28. IMP CoVac-1
    • Clinical trial ID:
      • Phase I/II: NCT04954469
        • Age subgroups: 18 years and above
        • Location: Germany
      • Phase I: NCT04546841
        • Age subgroups: 18-55 years, 56-74 years, 75 years and above
        • Location: Germany
    • Type: Subunit vaccine
    • Manufacturer: University Hospital Tuebingen
    • VIOLIN: 5826
    • VO: VO_0005190
  29. KBP-COVID-19
    • Clinical trial ID:
      • Phase I/II: NCT04473690
        • Age subgroups: 18-49 years, 50-70 years
        • Location: USA
    • Type: Subunit vaccine
    • Manufacturer: Kentucky BioProcessing
    • VIOLIN: 5792
    • VO: VO_0005171
  30. Koçak-19 Inaktif Adjuvanlı COVID-19 Vaccine
    • Clinical trial ID:
      • Phase II: NCT05035238
        • Age subgroups: 18-64 years
        • Location: Turkey
      • Phase I: NCT04838080
        • Age subgroups: 18-55 years
        • Location: Turkey
    • Type: Inactivated or "killed" vaccine
    • Manufacturer: Kocak Farma
    • VIOLIN: 5860
    • VO: VO_0005253
  31. LV-SMENP-DC
    • Clinical trial ID:
      • Phase I/II: NCT04276896
        • Age subgroups: 6 months to 80 years
        • Location: China
    • Type: Recombinant vector vaccine
    • Manufacturer: Shenzhen Geno-Immune Medical Institute
    • VIOLIN: 5808
    • VO: VO_0005091
  32. mRNA-1283
    • Clinical trial ID:
      • Phase II: NCT05137236
        • Age subgroups: People 18 years and above who have received their second dose of mRNA-1273 vaccine at least 6 months prior to screening and enrollment
        • Location: USA
      • Phase I: NCT04813796
        • Age subgroups: Unvaccinated people 18-55 years
        • Location: USA
    • Type: mRNA vaccine
    • Manufacturer: Moderna, NIAID
    • VIOLIN: 5868
    • VO: VO_0005185
  33. MRT5500
    • Clinical trial ID:
      • Phase I/II: NCT04798027
        • Age subgroups: 18 years and above
        • Location: USA
    • Type: mRNA vaccine
    • Manufacturer: Sanofi Pasteur, Translate Bio
    • VIOLIN: 5850
    • VO: VO_0005241
  34. MVA-SARS-2-ST
    • Clinical trial ID:
      • Phase I/II: NCT04895449
        • Age subgroups:
          • Phase I: 18-64 years
          • Phase II: 18 years and above
        • Location: Germany
    • Type: Recombinant vector vaccine
    • Manufacturer: German Center for Infection Research
    • VIOLIN: 5871
    • VO: VO_0005262
  35. NDV-HXP-S
    • Clinical trial ID:
      • Phase I/II: NCT04764422
        • Age subgroups:
          • Phase I: 18-59 years
          • Phase II: 18-75 years
        • Location: Thailand
    • Type: Recombinant vector vaccine
    • Manufacturer: Icahn School of Medicine at Mount Sinai, Mahidol University
    • Publications:
      • Sun et al. Newcastle disease virus (NDV) expressing the spike protein of SARS-CoV-2 as a live virus vaccine candidate. EBioMedicine. 2020; 62; 103132. [PubMed: 33232870].
    • VIOLIN: 5841
    • VO: VO_0005235
  36. QazCoVac-P
    • Clinical trial ID:
      • Phase I/II: NCT04930003
        • Age subgroups:
          • Phase I: 18-50 years
          • Phase II: 18 years and above
        • Location: Kazakhstan
    • Type: Subunit vaccine
    • Manufacturer: Research Institute for Biological Safety Problems
    • VIOLIN: 5874
    • VO: VO_0005273
  37. RBD-HBsAg VLP
    • Clinical trial ID:
      • Phase I/II: ACTRN12620001308987
        • Age subgroups:
          • Phase I: 18-45 years
          • Phase II: 18-79 years
        • Location: Australia
      • Phase I/II: ACTRN12620000817943
        • Age subgroups:
          • Phase I: 18-45 years
          • Phase II: 18-79 years
        • Location: Australia
    • Type: Virus Like Particle
    • Manufacturer: Serum Institute of India, Accelegen Pty
    • VIOLIN: 5811
    • VO: VO_0005094
  38. S-268019
    • Clinical trial ID:
      • Phase I/II: jRCT2051200092
        • Age subgroups: 20-64 years
        • Location: Japan
    • Type: Subunit vaccine
    • Manufacturer: Shionogi
    • VIOLIN: 5813
    • VO: VO_0005096
  39. SCB-2020S
    • Clinical trial ID:
      • Phase II: NCT04950751
        • Age subgroups: 18 years and above
        • Location: Unknown
    • Type: Subunit vaccine
    • Manufacturer: Clover Biopharmaceuticals AUS Pty Ltd
    • VIOLIN: 5879
    • VO: VO_0005315
  40. SII B.1.351
    • Clinical trial ID:
      • Phase I/II: NCT05029856
        • Age subgroups: 18-64 years
        • Location: Australia
    • Type: Subunit vaccine
    • Manufacturer: Novavax
    • VIOLIN: 5885
    • VO: VO_0005333
  41. SII B.1.617.2
    • Clinical trial ID:
      • Phase I/II: NCT05029856
        • Age subgroups: 18-64 years
        • Location: Australia
    • Type: Subunit vaccine
    • Manufacturer: Novavax
    • VIOLIN: 5886
    • VO: VO_0005335
  42. SII Bivalent
    • Clinical trial ID:
      • Phase I/II: NCT05029856
        • Age subgroups: 18-64 years
        • Location: Australia
    • Type: Subunit vaccine
    • Manufacturer: Novavax
    • VIOLIN: 5887
    • VO: VO_0005334
  43. VB10.2129
    • Clinical trial ID:
      • Phase I/II: NCT05069623
        • Age subgroups: 18-60 years
        • Location: Norway
    • Type: DNA vaccine
    • Manufacturer: Vaccibody AS
    • VIOLIN: 5893
    • VO: VO_0005340
  44. VB10.2210
    • Clinical trial ID:
      • Phase I/II: NCT05069623
        • Age subgroups: 18-60 years
        • Location: Norway
    • Type: DNA vaccine
    • Manufacturer: Vaccibody AS
    • VIOLIN: 5894
    • VO: VO_0005341
  45. VBI-2902a
    • Clinical trial ID:
      • Phase I/II: NCT04773665
        • Age subgroups:
          • Phase I: 18-54 years
          • Phase II: 18-54 years, 55-65 years, 66 years and above
        • Location: Canada
    • Type: Virus Like Particle
    • Manufacturer: VBI Vaccines Inc.
    • VIOLIN: 5843
    • VO: VO_0005238
  46. VXA-CoV2-1
    • Clinical trial ID:
      • Phase II: NCT05067933
        • Age subgroups: 18-75 years
        • Location: USA
      • Phase I: NCT04563702
        • Age subgroups: 18-54 years
        • Location: USA
    • Type: Recombinant vector vaccine
    • Manufacturer: Vaxart
    • VIOLIN: 5832
    • VO: VO_0005196

Provenance: All data in Cov19VaxKB originates from manual curation of reliable resources

Note: The page was updated on January 7, 2022. We plan to update this page on a weekly or even a daily basis. Please provide us with any new information that you believe would be useful if included on the website.