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Phase II COVID-19 Vaccines

This site presents an alphabetically-ordered list of COVID-19 vaccines that are currently in Phase II clinical trials as of September 4, 2021.

Current Phase II COVID-19 vaccines include:

Contents:

1. 202-CoV
2. AdCLD-CoV19
3. AG0302-COVID19
4. AKS-452
5. ARCT-021
6. AV-COVID-19
7. BECOV2A
8. CIGB-669
9. COH04S1
10. COVAC
11. COVID-19 subunit vaccine by HIPRA
12. COVID-19 subunit vaccine by National Vaccine and Serum Institute of China
13. COVID-19 VLP vaccine by the Scientific and Technological Research Council of Turkey
14. COVID-eVax
15. COVIVAC
16. DelNS1-2019-nCoV-RBD-OPT1
17. DS-5670a
18. EuCorVac-19
19. EXG-5003
20. FAKHRAVAC
21. FINLAY-FR-1
22. GLS-5310
23. GX-19
24. hAd5-COVID-19
25. KBP-COVID-19
26. KD-414
27. LV-SMENP-DC
28. mRNA-1273.351
29. MRT5500
30. MVA-SARS-2-ST
31. NDV-HXP-S
32. QazCoVac-P
33. Razi Cov Pars
34. RBD-HBsAg VLP
35. S-268019
36. SCB-2020S
37. V-01
38. VBI-2902a

1. 202-CoV
• Clinical trial ID:
• Phase II: NCT04990544
• Age subgroups: 18-59 years; 60 years and above
• Location: China
• Phase I: NCT04982068
• Age subgroups: 18-59 years; 60 years and above
• Location: China
• Type: Subunit vaccine
• Manufacturer: Shanghai Zerun Biotechnology, Walvax Biotechnology, CEPI
• VIOLIN: 5835
• VO: VO_0005320
2. AdCLD-CoV19
• Clinical trial ID:
• Phase I/II: NCT04666012
• Age subgroups: 19-64 years
• Location: South Korea
• Type: Recombinant vector vaccine
• Manufacturer: Cellid Co., Ltd.
• VIOLIN: 5800
• VO: VO_0004996
3. AG0302-COVID19
• Clinical trial ID:
• Phase I/II: NCT04993586
• Age subgroups: 18 years and above
• Location: Japan
• Type: DNA vaccine
• Manufacturer: AnGes, Inc.
• VIOLIN: 5882
• VO: VO_0005322
4. AKS-452
• Clinical trial ID:
• Phase I/II: NCT04681092
• Age subgroups: 18-55 years
• Location: Netherlands
• Type: Subunit vaccine
• Manufacturer: University Medical Center Groningen, Akston Biosciences Inc.
• VIOLIN: 5834
• VO: VO_0004999
5. ARCT-021
• Other names: LUNAR-COV19
• Clinical trial ID:
• Phase II: NCT04728347
• Age subgroups: 18-55 years (21-55 years in Singapore), 56 years and above
• Location: USA, Singapore
• Phase II: NCT04728347
• Age subgroups: 21-80 years
• Location: Singapore
• Phase I/II: NCT04480957
• Age subgroups:
• Phase I: 21-55 years
• Phase II: 21-55 years, 56-80 years
• Location: Singapore
• Type: mRNA vaccine
• Manufacturer: Arcturus Therapeutics, Duke-NUS Medical School
• VIOLIN: 5781
• VO: VO_0005164
6. AV-COVID-19
• Clinical trial ID:
• Phase II: NCT05007496
• Age subgroups: 18 years and above
• Location: Indonesia
• Phase I/II: NCT04386252
• Age subgroups: 18 years and above
• Location: USA
• Type: Recombinant vector vaccine
• Manufacturer: Aivita Biomedical, Inc.
• VIOLIN: 5801
• VO: VO_0005079
7. BECOV2A
• Clinical trial ID:
• Phase I/II: CTRI/2020/11/029032
• Age subgroups:
• Phase I: 18-55 years
• Phase II: 18-65 years
• Location: India
• Type: Subunit vaccine
• Manufacturer: Biological E
• VIOLIN: 5802
• VO: VO_0005081
8. CIGB-669
• Clinical trial ID:
• Phase I/II: RPCEC00000345
• Age subgroups:
Phase I: 19-54 years
Phase II: 19-80 years
• Location: Cuba
• Type: Subunit vaccine
• Manufacturer: Center for Genetic Engineering and Biotechnology (CIGB)
• VIOLIN: 5804
• VO: VO_0005083
9. COH04S1
• Clinical trial ID:
• Phase II: NCT04977024
• Age subgroups: 18 years and above
• Location: USA
• Phase I: NCT04639466
• Age subgroups: 18-55 years
• Location: USA
• Type: Recombinant vector vaccine
• Manufacturer: City of Hope Medical Center
• Publications
• Chiuppesi et al. Development of a multi-antigenic SARS-CoV-2 vaccine candidate using a synthetic poxvirus platform. Nat Commun. 2020; 11(1); 6121. [PubMed: 33257686].
• VIOLIN: 5819
• VO: VO_0005176
10. COVAC
• Clinical trial ID:
• Phase I/II: NCT04702178
• Age subgroups: 18-54 years, 55-69 years, 70 years and above
• Location: Canada
• Type: Subunit vaccine
• Manufacturer: Vaccine and Infectious Disease Organization (VIDO), SEPPIC, Vaccine Formulation Institute (VFI)
• VIOLIN: 5830
• VO: VO_0005194
11. COVID-19 subunit vaccine by HIPRA
• Clinical trial ID:
• Phase I/II: NCT05007509
• Age subgroups: 18-39 years
• Location: Spain
• Type: Subunit vaccine
• Manufacturer: Laboratorios Hipra, S.A.
• VIOLIN: 5883
• VO: VO_0005321
12. COVID-19 subunit vaccine by National Vaccine and Serum Institute of China
• Clinical trial ID:
• Phase I/II: NCT04869592
• Age subgroups:
• Phase I: 3-8 years, 9-17 years, 18-59 years, 60-69 years, 70 years and above
• Phase II: 3-8 years, 9-17 years, 18-59 years, 60-69 years, 70 years and above
• Location: China
• Type: Subunit vaccine
• Manufacturer: National Vaccine and Serum Institute, China
• VIOLIN: 5857
• VO: VO_0005248
13. COVID-19 VLP vaccine by the Scientific and Technological Research Council of Turkey
• Clinical trial ID:
• Phase II: NCT04962893
• Age subgroups: 18-59 years
• Location: Turkey
• Phase I: NCT04818281
• Age subgroups: 18-59 years
• Location: Turkey
• Type: Virus like particle vaccine
• Manufacturer: The Scientific and Technological Research Council of Turkey
• VIOLIN: 5862
• VO: VO_0005251
14. COVID-eVax
• Clinical trial ID:
• Phase I/II: NCT04788459
• Age subgroups: 18-64 years, 65 years and above
• Location: Italy
• Type: DNA vaccine
• Manufacturer: Takis, Rottapharm Biotech
• VIOLIN: 5838
• VO: VO_0005230
15. COVIVAC
• Clinical trial ID:
• Phase I/II: NCT04830800
• Age subgroups:
• Phase I: 18-59 years
• Phase II: 18-75 years
• Location: Vietnam
• Type: Recombinant vector vaccine
• Manufacturer: Institute of Vaccines and Medical Biologicals, Vietnam
• VIOLIN: 5855
• VO: VO_0005246
16. DelNS1-2019-nCoV-RBD-OPT1
• Clinical trial ID:
• Phase II: ChiCTR2000039715
• Age subgroups: 18 years and above
• Location: China
• Type: Recombinant vector vaccine
• Manufacturer: University of Hong Kong, Xiamen University, Beijing Wantai Biological Pharmacy
• VIOLIN: 5806
• VO: VO_0005087
17. DS-5670a
• Clinical trial ID:
• Phase I/II: NCT04821674
• Age subgroups: 20-64 years, 65-74 years
• Location: Japan
• Type: mRNA vaccine
• Manufacturer: Daiichi Sankyo Co., Ltd.
• VIOLIN: 5854
• VO: VO_0005245
18. EuCorVac-19
• Clinical trial ID:
• Phase I/II: NCT04783311
• Age subgroups:
• Phase I: 19-50 years
• Phase II: 19-75 years
• Location: South Korea
• Type: Subunit vaccine
• Manufacturer: EuBiologics Co., Ltd.
• VIOLIN: 5848
• VO: VO_0005232
19. EXG-5003
• Clinical trial ID:
• Phase I/II: NCT04863131
• Age subgroups: 20-55 years
• Location: Japan
• Type: mRNA vaccine
• Manufacturer: Elixirgen Therapeutics, Inc.
• VIOLIN: 5858
• VO: VO_0005249
20. FAKHRAVAC
• Other names: MIVAC
• Clinical trial ID:
• Phase II: IRCT20210206050259N2
• Age subgroups: 18-70 years
• Location: Iran
• Phase I: IRCT20210206050259N1
• Age subgroups: 18-55 years
• Location: Iran
• Type: Inactivated or "killed" vaccine
• Manufacturer: Organization of Defensive Innovation and Research
• VIOLIN: 5849
• VO: VO_0005239
21. FINLAY-FR-1
• Clinical trial ID:
• Phase II: IFV/COR/11
• Age subgroups: 19-80 years
• Location: Cuba
• Phase I/II: IFV/COR/04
• Age subgroups: 19-59 years, 60-80 years
• Location: Cuba
• Type: Subunit vaccine
• Manufacturer: Instituto Finlay de Vacunas, Cuba
• VIOLIN: 5853
• VO: VO_0005244
22. GLS-5310
• Clinical trial ID:
• Phase I/II: NCT04673149
• Age subgroups:
  • Phase I: 19-50 years
  • Phase II: 19-65 years
• Location: South Korea
• Type: DNA vaccine
• Manufacturer: GeneOne Life Science, Inc.
• VIOLIN: 5807
• VO: VO_0005089
23. GX-19
• Clinical trial ID:
• Phase I/II: NCT04715997
• Age subgroups: 18-55 years
• Location: South Korea
• Phase I/II: NCT04445389
• Age subgroups: 18-50 years
• Location: South Korea
• Type: DNA vaccine
• Manufacturer: Genexine
• VIOLIN: 5788
• VO: VO_0005170
24. hAd5-COVID-19
• Clinical trial ID:
• Phase II: NCT04843722
• Age subgroups: 18-80 years
• Location: USA
• Phase II: NCT04845191
• Age subgroups: 18-80 years
• Location: USA
• Phase I: NCT04732468
• Age subgroups: 18-55 years
• Location: USA
• Phase I: NCT04591717
• Age subgroups: 18-55 years
• Location: USA
• Phase I: NCT04710303
• Age subgroups: 18-50 years
• Location: USA
• Type: Recombinant vector vaccine
• Manufacturer: ImmunityBio, Inc.; NantKwest Inc.
• VIOLIN: 5825
• VO: VO_0005189
25. IMP CoVac-1
• Clinical trial ID:
• Phase I/II: NCT04954469
• Age subgroups: 18 years and above
• Location: Germany
• Phase I: NCT04546841
• Age subgroups: 18-55 years, 56-74 years, 75 years and above
• Location: Germany
• Type: Subunit vaccine
• Manufacturer: University Hospital Tuebingen
• VIOLIN: 5826
• VO: VO_0005190
26. KBP-COVID-19
• Clinical trial ID:
• Phase I/II: NCT04473690
• Age subgroups: 18-49 years, 50-70 years
• Location: USA
• Type: Subunit vaccine
• Manufacturer: Kentucky BioProcessing
• VIOLIN: 5792
• VO: VO_0005171
27. KD-414
• Clinical trial ID:
• Phase I/II: jRCT2071200106
• Age subgroups: 20-64 years, 65 years and above
• Location: Japan
• Type: Inactivated or "killed" vaccine
• Manufacturer: KM Biologics Co., Ltd.
• VIOLIN: 5859
• VO: VO_0005250
28. LV-SMENP-DC
• Clinical trial ID:
• Phase I/II: NCT04276896
• Age subgroups: 6 months to 80 years
• Location: China
• Type: Recombinant vector vaccine
• Manufacturer: Shenzhen Geno-Immune Medical Institute
• VIOLIN: 5808
• VO: VO_0005091
29. mRNA-1273.351
• Clinical trial ID:
• Phase II: NCT04847050
• Age subgroups: 18 years and above
• Location: USA
• Phase I: NCT04785144
• Age subgroups
• Cohort 1: Previously vaccinated people 18 years and above
• Cohort 2: Unvaccinated people 18-55 years
• Location: USA
• Type: mRNA vaccine
• Manufacturer: Moderna, NIAID
• VIOLIN: 5846
• VO: VO_0005233
30. MRT5500
• Clinical trial ID:
• Phase I/II: NCT04798027
• Age subgroups: 18 years and above
• Location: USA
• Type: mRNA vaccine
• Manufacturer: Sanofi Pasteur, Translate Bio
• VIOLIN: 5850
• VO: VO_0005241
31. MVA-SARS-2-ST
• Clinical trial ID:
• Phase I/II: NCT04895449
• Age subgroups:
• Phase I: 18-64 years
• Phase II: 18 years and above
• Location: Germany
• Type: Recombinant vector vaccine
• Manufacturer: German Center for Infection Research
• VIOLIN: 5871
• VO: VO_0005262
32. NDV-HXP-S
• Clinical trial ID:
• Phase I/II: NCT04764422
• Age subgroups:
• Phase I: 18-59 years
• Phase II: 18-75 years
• Location: Thailand
• Type: Recombinant vector vaccine
• Manufacturer: Icahn School of Medicine at Mount Sinai, Mahidol University
• Publications:
• Sun et al. Newcastle disease virus (NDV) expressing the spike protein of SARS-CoV-2 as a live virus vaccine candidate. EBioMedicine. 2020; 62; 103132. [PubMed: 33232870].
• VIOLIN: 5841
• VO: VO_0005235
33. QazCoVac-P
• Clinical trial ID:
• Phase I/II: NCT04930003
• Age subgroups:
• Phase I: 18-50 years
• Phase II: 18 years and above
• Location: Kazakhstan
• Type: Subunit vaccine
• Manufacturer: Research Institute for Biological Safety Problems
• VIOLIN: 5874
• VO: VO_0005273
34. Razi Cov Pars
• Clinical trial ID:
• Phase II: IRCT20201214049709N2
• Age subgroups: 18-70 years
• Location: Iran
• Phase I: IRCT20201214049709N1
• Age subgroups: 18-55 years
• Location: Iran
• Type: Subunit vaccine
• Manufacturer: Razi Vaccine and Serum Research Institute
• VIOLIN: 5779
• VO: VO_0005226
35. RBD-HBsAg VLP
• Clinical trial ID:
• Phase I/II: ACTRN12620001308987
• Age subgroups:
• Phase I: 18-45 years
• Phase II: 18-79 years
• Location: Australia
• Phase I/II: ACTRN12620000817943
• Age subgroups:
• Phase I: 18-45 years
• Phase II: 18-79 years
• Location: Australia
• Type: Virus Like Particle
• Manufacturer: Serum Institute of India, Accelegen Pty
• VIOLIN: 5811
• VO: VO_0005094
36. S-268019
• Clinical trial ID:
• Phase I/II: jRCT2051200092
• Age subgroups: 20-64 years
• Location: Japan
• Type: Subunit vaccine
• Manufacturer: Shionogi
• VIOLIN: 5813
• VO: VO_0005096
37. SCB-2020S
• Clinical trial ID:
• Phase II: NCT04950751
• Age subgroups: 18 years and above
• Location: Unknown
• Type: Subunit vaccine
• Manufacturer: Clover Biopharmaceuticals AUS Pty Ltd
• VIOLIN: 5879
• VO: VO_0005315
38. V-01
• Clinical trial ID:
• Phase II: ChiCTR2100045107
• Age subgroups: 18-59 years, 60-69 years, 70 years and above
• Location: China
• Type: Subunit vaccine
• Manufacturer: Livzon Mabpharm Inc.
• VIOLIN: 5856
• VO: VO_0005247
39. VBI-2902a
• Clinical trial ID:
• Phase I/II: NCT04773665
• Age subgroups:
• Phase I: 18-54 years
• Phase II: 18-54 years, 55-65 years, 66 years and above
• Location: Canada
• Type: Virus Like Particle
• Manufacturer: VBI Vaccines Inc.
• VIOLIN: 5843
• VO: VO_0005238

Provenance: All data in Cov19VaxKB originates from manual curation of reliable resources

Note: The page was updated on September 4, 2021. We plan to update this page on a weekly or even a daily basis. Please provide us with any new information that you believe would be useful if included on the website.