Cov19VaxKB: COVID-19 Vaccine Knowledgebase

Preclinical COVID-19 Vaccines

This site presents a list of COVID-19 vaccines that are currently in preclinical research studies as of July 23, 2022.

Existing preclinical COVID-19 vaccines include:

Contents:

Cell-based vaccines
DNA vaccines
Inactivated vaccines
Live, attenuated vaccines
Recombinant vector vaccines
RNA vaccines
Subunit vaccines
Virus-Like Particle vaccines

Cell-based vaccines
1. COVID-19 cellular based vaccine by Cell Tech Pharmed
DNA vaccines
1. COVID-19 DNA vaccine by Biosun Pharmed
2. COVID-19 DNA vaccine by Center of Genomics and Bioinformatics of Academy of Science of Uzbekistan
3. COVID-19 DNA vaccine by Chula Vaccine Research Center
4. COVID-19 DNA vaccine by Ege University
5. COVID-19 DNA vaccine by Globe Biotech
6. COVID-19 DNA vaccine by Immunomic Therapeutics, EpiVax, and PharmaJet
7. COVID-19 DNA vaccine by Inserm
8. COVID-19 DNA vaccine by Karolinska Institute and Cobra Biologics
9. COVID-19 DNA vaccine by Mediphage Bioceuticals and the University of Waterloo
10. COVID-19 DNA vaccine by the National Institute of Chemistry of Slovenia
11. COVID-19 DNA vaccine by the National Research Centre of Egypt
12. COVID-19 DNA vaccine by Vaccibody
13. COVIDITY
14. COVIGEN
15. COVIGENIX VAX-001
16. DIOS-CoVax2
Inactivated vaccines
1. COVID-19 inactivated vaccine by Institute Butantan, Dynavax, and PATH
2. COVID-19 inactivated vaccine by KM Biologics
3. COVID-19 inactivated vaccine by Milad Pharmaceutics Co.
4. COVID-19 inactivated vaccine by the National Research Centre of Egypt
5. COVID-19 inactivated vaccine by Osaka University, BIKEN, NIBIOHN
6. COVID-19 inactivated vaccine by Paya Fan Yakhte Alborz
7. COVID-19 inactivated vaccine by Selcuk University
8. COVID-19 inactivated vaccine by Sinovac and Dynavax
9. COVID-19 inactivated vaccine by Valneva and Dynavax
10. COVID-19 inactivated vaccine by Zista Kian Azma Co.
Live, attenuated vaccines
1. COVID-19 live, attenuated vaccine by ALtraBio and TheRex
2. COVID-19 live, attenuated vaccine by Indian Immunologicals Ltd and Griffith University
3. COVID-19 live, attenuated vaccine by Institut Pasteur Lille
4. COVID-19 live, attenuated vaccine by by Mehmet Ali Aydinlar University and Acıbadem Labmed Health Services A.S.
Recombinant vector vaccines
1. 3934 Vac
2. AAVCOVID vaccine
3. CoraVax
4. COVID-19 intranasal live viral vectored vaccine by BiOCAD and IEM
5. COVID-19 measles vector vaccine by DZIF – German Center for Infection Research and CanVirex AG
6. COVID-19 measles vector vaccine by FBRI SRC VB VECTOR
7. COVID-19 measles vector vaccine by Cadila Healthcare Limited
8. COVID-19 Intranasal recombinant vector vaccine by FBRI SRC VB VECTOR
9. COVID-19 Newcastle disease virus vector vaccine expressing the wild-type S protein by Icahn School of Medicine
10. COVID-19 Newcastle disease virus vector vaccine expressing the membrane-anchored S protein by Icahn School of Medicine
11. COVID-19 recombinant vector vaccine by AIOVA
12. COVID-19 recombinant vector vaccine by Ankara University
13. COVID-19 recombinant vector vaccine by Aurobindo
14. COVID-19 recombinant vector vaccine by Centro Nacional Biotecnología
15. COVID-19 recombinant vector vaccine by Chengdu Kanghua Biological Products Co., Ltd.
16. COVID-19 recombinant vector vaccine by Erciyes University
17. COVID-19 recombinant vector vaccine by Fundação Oswaldo Cruz and Instituto Buntantan
18. COVID-19 recombinant vector vaccine by Greffex
19. COVID-19 recombinant vector vaccine by Home Iman Zist Fanavar
20. COVID-19 recombinant vector vaccine by IAVI and Merck
21. COVID-19 recombinant vector vaccine by ID Pharma
22. COVID-19 recombinant vector vaccine by IDIBAPS-Hospital Clinic
23. COVID-19 recombinant vector vaccine by Intravacc, Wageningen Bioveterinary Research, and Utrecht University
24. COVID-19 recombinant vector vaccine by KU Leuven
25. COVID-19 recombinant vector vaccine by Lancaster University
26. COVID-19 recombinant vector vaccine by the National Research Centre of Egypt
27. COVID-19 recombinant adenovirus vector (type 5) vaccine by Pasteur Institute
28. COVID-19 recombinant adenovirus vector (ChAdOx1) vaccine by Pasteur Institute
29. COVID-19 recombinant vector vaccine by Sorbonne University
30. COVID-19 recombinant vector vaccine by Theravectys – Institut Pasteur
31. COVID-19 recombinant vector vaccine by University of Helsinki and University of Eastern Finland
32. COVID-19 recombinant vector vaccine by University of Hong Kong
33. COVID-19 recombinant vector vaccine by University of Manitoba
34. COVID-19 recombinant vector vaccine by University of Western Ontario
35. COVID-19 recombinant vector vaccine by UW–Madison, FluGen, and Bharat Biotech
36. COVID-19 recombinant vector vaccine by Valo Therapeutics
37. COVID-19 recombinant vector vaccine by Vaxart
38. COVID-19 VSV vector vaccine by FBRI SRC VB VECTOR
39. GEO-CM01 vaccine
40. OraPro-COVID-19 vaccine
41. PIV5-based COVID-19 vaccine
42. TNX-1800 vaccine
43. VIR4VAC COVID-19 vaccine
RNA vaccines
1. BANCOVID
2. COVID-19 RNA vaccine by BIOCAD
3. COVID-19 RNA vaccine by CEA
4. COVID-19 RNA vaccine by Cell Tech Pharmed
5. COVID-19 RNA vaccine by Centro Nacional Biotecnología
6. COVID-19 RNA vaccine by Certest Biotec
7. COVID-19 RNA vaccine by China CDC, Tongji University, and Stermina
8. COVID-19 RNA vaccine by eTheRNA
9. COVID-19 RNA vaccine by FBRI SRC VB VECTOR
10. COVID-19 RNA vaccine by Greenlight Biosciences
11. COVID-19 RNA vaccine by IDIBAPS-Hospital Clinic
12. COVID-19 RNA vaccine by Infectious Disease Research Institute and Amyris, Inc.
13. COVID-19 RNA vaccine by Max-Planck-Institute of Colloids and Interfaces
14. COVID-19 RNA vaccine by Medigen Vaccines Biologics Corp and Vaxess Technologies
15. COVID-19 RNA vaccine by Providence Therapeutics
16. COVID-19 RNA vaccine by ReNAP Co.
17. COVID-19 RNA vaccine by Selcuk University
18. COVID-19 RNA vaccine by University of Tokyo and Daiichi-Sankyo
19. COVID-19 RNA vaccine encoding RBD by Fudan University, Shanghai JiaoTong University, and RNACure Biopharma
20. COVID-19 RNA vaccine encoding VLP by Fudan University, Shanghai JiaoTong University, and RNACure Biopharma
21. MRT5500
22. RV1730
23. ZIP-1642
Subunit vaccines
1. ACvac1
2. CorVax
3. CoVepiT
4. COVID-19 nanoparticle vaccine by LakePharma
5. COVID-19 OMV-based vaccine by BiOMViS Srl and University of Trento
6. COVID-19 OMV-based vaccine by Quadram Institute Biosciences
7. COVID-19 plant-based protein subunit vaccine by Baiya Phytopharm and Chula Vaccine Research Center
8. COVID-19 protein subunit vaccine by AdaptVac
9. COVID-19 protein subunit vaccine by Akdeniz University
10. COVID-19 protein subunit vaccine by AJ Vaccines
11. COVID-19 protein subunit vaccine by AnyGo Technology
12. COVID-19 protein subunit vaccine by Applied Biotechnology Institute
13. COVID-19 protein subunit vaccine by Ataturk University
14. COVID-19 protein subunit vaccine by Baylor College of Medicine
15. COVID-19 protein subunit vaccine by Bio Farma and Baylor College of Medicine
16. COVID-19 protein subunit vaccine by Biological E. Limited
17. COVID-19 protein subunit vaccine by Biosun Pharmed
18. COVID-19 protein subunit vaccine by Bogazici University
19. COVID-19 protein subunit vaccine by CEA and CNRS
20. COVID-19 protein subunit vaccine by Center for Advanced Technologies in Uzbekistan
21. COVID-19 protein subunit vaccine by Chulalongkorn University and Thailand GPO
22. COVID-19 protein subunit vaccine by CinnaGen Co
23. COVID-19 protein subunit vaccine by EpiVax and University of Georgia
24. COVID-19 protein subunit vaccine by ExpreS2ion
25. COVID-19 protein subunit vaccine by Farmacológicos Veterinarios SAC and Universidad Peruana Cayetano Heredia
26. COVID-19 protein subunit vaccine by FBRI SRC VB VECTOR
27. COVID-19 protein subunit vaccine by FSUE SPbSRIVS FMBA of Russia
28. COVID-19 protein subunit vaccine by Generex and EpiVax
29. COVID-19 protein subunit vaccine by Hacettepe University
30. COVID-19 protein subunit vaccine by Helix Biogen Consult, Ogbomoso
31. COVID-19 protein subunit vaccine by iBio and CC-Pharming
32. COVID-19 protein subunit vaccine by ImmunoPrecise and LiteVax BV
33. COVID-19 protein subunit vaccine by Intravacc and Epivax
34. COVID-19 protein subunit vaccine by Iran
35. COVID-19 protein subunit vaccine by Izmir Biomedicine and Genome Center
36. COVID-19 protein subunit vaccine by Kazakh National Agrarian University
37. COVID-19 protein subunit vaccine by Kazakh National Agrarian University and National Scientific Center for Especially Dangerous Infections
38. COVID-19 protein subunit vaccine by LinkinVax, VRI, and Inserm
39. COVID-19 protein subunit vaccine by Lomonosov Moscow State University
40. COVID-19 protein subunit vaccine by Marmara University
41. COVID-19 protein subunit vaccine by Max-Planck-Institute of Colloids and Interfaces
42. COVID-19 protein subunit vaccine by MIGAL Galilee Research Institute
43. COVID-19 protein subunit vaccine by MOGAM Institute for Biomedical Research and GC Pharma
44. COVID-19 protein subunit vaccine by Mynvax
45. COVID-19 protein subunit vaccine by Nanografi Nano Technology, Middle East Technical University, and Ankara University
46. COVID-19 protein subunit vaccine by National Research Centre of Egypt
47. COVID-19 protein subunit vaccine by Neovii and Tel Aviv University
48. COVID-19 protein subunit vaccine by Ohio State University and Kazakh National Agrarian University
49. COVID-19 protein subunit vaccine by OncoGen
50. COVID-19 protein subunit vaccine by Osaka University, BIKEN, and National Institutes of Biomedical Innovation
51. COVID-19 protein subunit vaccine by Pharmada Pharmaceuticals
52. COVID-19 protein subunit vaccine by Rahpouyan Fanavar Sadegh
53. COVID-19 protein subunit vaccine by Saint-Petersburg Scientific Research Institute of Vaccines and Serums
54. COVID-19 protein subunit vaccine by Shionogi, National Institute of Infectious Disease, and UMN Pharma
55. COVID-19 protein subunit vaccine by Tampere University
56. COVID-19 protein subunit vaccine by University of Alberta
57. COVID-19 protein subunit vaccine by University of San Martin and CONICET
58. COVID-19 protein subunit vaccine by University of Virginia
59. COVID-19 protein subunit vaccine by Vabiotech, Vietnam, and University of Bristol
60. COVID-19 protein subunit vaccine by Vacino Biotech
61. COVID-19 protein subunit vaccine by Vaxinano, CEA, and INRAE
62. COVID-19 protein subunit vaccine by VIDO-InterVac and University of Saskatchewan
63. COVID-19 protein subunit vaccine by WRAIR and USAMRIID
64. COVID-19 protein subunit vaccine by Yıldız Technical University
65. COVID-19 protein subunit vaccine by Yisheng Biopharma
66. COVID-19 protein subunit vaccine by Zist Salak
67. COVID-19 XWG-03
68. DPX-COVID-19
69. EPV-CoV19
70. FlowVax COVID-19
71. gp96-Ig-S vaccine
72. NYVAC-KC
73. PBIMA-SOLVx COVID-19
74. PittCoVacc
75. TerraCoV2
Virus-Like Particle vaccines
1. COVID-19 virus-like particle vaccine (Myxoma virus) by Arizona State University
2. COVID-19 virus-like particle vaccine (plasmid) by Arizona State University
3. COVID-19 virus-like particle vaccine by ARTES Biotechnology
4. COVID-19 virus-like particle vaccine by Berna Biotech Pharma
5. COVID-19 virus-like particle vaccine by Bezmialem Vakif University
6. COVID-19 virus-like particle vaccine by Doherty Institute
7. COVID-19 virus-like particle vaccine by ExcepGen
8. COVID-19 virus-like particle vaccine by Imophoron Ltd and Bristol University’s Max Planck Centre
9. COVID-19 virus-like particle vaccine by IrsiCaixa AIDS Research, IRTA-CReSA, Barcelona Supercomputing Centre, and Grifols
10. COVID-19 virus-like particle vaccine by Mahidol University, Government Pharmaceutical Organization, and Siriraj Hospital
11. COVID-19 virus-like particle vaccine by Max Planck Institute for Dynamics of Complex Technical Systems
12. COVID-19 virus-like particle vaccine by Navarrabiomed
13. COVID-19 virus-like particle vaccine by OSIVAX
14. COVID-19 virus-like particle vaccine by Saiba
15. COVID-19 virus-like particle vaccine by Shiraz University
16. COVID-19 virus-like particle vaccine by Tampere University
17. COVID-19 virus-like particle vaccine by University of Manitoba
18. COVID-19 virus-like particle vaccine by University of Sao Paulo
19. COVID-19 virus-like particle vaccine by VBI Vaccines

Provenance: All data in Cov19VaxKB originates from manual curation of various resources, including the WHO's COVID-19 Vaccine Tracker.

Note: The page was updated on July 23, 2022. Please provide us with any new information that you believe would be useful if included on the website.