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FabB/FabF
Gene Name	FabB/FabF
Sequence Strain (Species/Organism)	Plasmodium falciparum 3D7
NCBI Gene ID	3885996
NCBI Protein GI	296004726
Locus Tag	PFF1275c
Genbank Accession	AL844505
Protein Accession	XP_966246
3D structure: PDB ID	1OB1
Taxonomy ID	36329
Chromosome No	6
Gene Starting Position	1061115
Gene Ending Position	1062891
Gene Strand (Orientation)	-
Protein pI	9.25
Protein Weight	50967.34
Protein Length	473
DNA Sequence	>gi\|86176855:1061115-1062891 Plasmodium falciparum 3D7 chromosome 6 ATCACTTTACAATTTTTTTGAAAAGTAATGCTGTGTTATGGCCTCCAAATCCCAAATTTGTATTGAGAGA TATATCAATATTTTCCTTTGCATGAATATATTTATTAGGTGTATAATTTAGATCACAATCTGGGTCCTTA TATTCATAATTAATAGTAGGTGGTATAATATTTGTTTGCATAGTTTTAAGACATACAATAGATTCTATAG CTCCAGCAGCACCTATACAATGTCCTGTCATACTTTTAGTTGATGATATATATAATTTGTATGCATGATC TTTGAAAACATTTTTAAAAACCTTGGTTTCTATTTTATCATTTAAATTTGTTGAAGTACCATGTGCATTA ATATATTTAACGTCATTTATGTTTATATTTGCATTTTTTAATGCTTTATGAATAGAATTTGTTAAACCTT TCCCATTAGGTTCTGGTGCAGTAATATGGTATGCATCACATTCTGAAGAATATGAAATAATTTCTCCATA TATTGGTGCATTTCTTTTTATTGCATGTTCGTATGATTCTAGAATTAAGATGCCTGAACCTTCTCCCATA ACGAAACCACTTCTTTTTAAATCGAAGGGTCTACAACCTTTTTTTGGATTATCGTTATAACCTGTACATA AAGCCTTTAATGAATTGAATCCAGCAAAACTTATAGGAGTTATACTAGCTTCAGTTCCACCACATATCAT AACATCATACTCTTTATATTTTATATATCTATAGGCTTCACCTATTGTGTTACCAGACGTAGCACATGCA CTTAACATACCAAGAGAGATCCCTCTAATATTGTTTTCGATAGATACATATCCAGATGGAGTATTTGCTA TCATTGCAGGTATTAAATATGGTGTTATTCTTTTATGTCCTTTTTCATACATTGTTTTCATTTCTTTTTC TAAAAATCTTAGTCCACCTATGCCACTACCTATGATAGTACCTGTTTTATCTTTGTCTAATTTTTCCAAA TTTAGTTTTGCATCGTCTAAAGCTAAACGTGTGGCTGCGACTGCATAATGAGTACAATCATCATTACGAT TAACATCTTTTTTATTTGTGTAATAATCACTAGGATTAAAATCGCTTTTCTTTATTTCACTACCAATACC ACATGACATACCGGTTATATCAAATTTTGTAATTTTATCTATTGATGTATATCCATTTATAATATTATTC CAAAAATGTTCTATGCCAATCCCTAATCCAGTTACTACCCCTACACCTGTGCACACCACTCTAGAAGTCT AAATAAAAAATAAAAGAATTAAGAAAATTAAAATATATATAAAAATAAATGTATAGCATATTATTACTTT AATCATTTTTTACAATTTGTATATATCACATTTTATAAAACTATATAAATATAAATATATATATATATAT ATATATATATTATATATATTATATATTTTATTTAGTACTTCACAAAGATTTTTCATTTCTCTCGAATTGT ACAACTTGAAACCTTTAAAATAATTCTTGGATATTCCAGGTATACCCCTTTTAATGAAGGCATACCTTTT ACTGTTAACCTACATATGAAAATACATGGAGTATATATTATGACATGATTAATGTTTTTTTTTTTTTTTT TTTTTTTTTCTTTTCTACATCTAATATTCATATGGCACATGCATATGTTTGAAAGGGGAAACATATATTA ACTATTATGTTTGTTTTATTTTATTTTTAGAATTGTAGCATTACTTGTAGCACATAAAAGAACAGGAAAT AATATATTTTTATAATGTATTTTCTCA
Protein Sequence	>gi\|296004726\|ref\|XP_966246.2\| 3-oxoacyl-acyl-carrier protein synthase I/II [Plasmodium falciparum 3D7] MRKYIIKIYYFLFFYVLQVNSKRYAFIKRGIPGISKNYFKGFKLYNSREMKNLCETSRVVCTGVGVVTGL GIGIEHFWNNIINGYTSIDKITKFDITGMSCGIGSEIKKSDFNPSDYYTNKKDVNRNDDCTHYAVAATRL ALDDAKLNLEKLDKDKTGTIIGSGIGGLRFLEKEMKTMYEKGHKRITPYLIPAMIANTPSGYVSIENNIR GISLGMLSACATSGNTIGEAYRYIKYKEYDVMICGGTEASITPISFAGFNSLKALCTGYNDNPKKGCRPF DLKRSGFVMGEGSGILILESYEHAIKRNAPIYGEIISYSSECDAYHITAPEPNGKGLTNSIHKALKNANI NINDVKYINAHGTSTNLNDKIETKVFKNVFKDHAYKLYISSTKSMTGHCIGAAGAIESIVCLKTMQTNII PPTINYEYKDPDCDLNYTPNKYIHAKENIDISLNTNLGFGGHNTALLFKKIVK
Molecule Role	Virmugen
Molecule Role Annotation	A genetically attenuated parasite (GAP) with a mutation in the FabB/FabF gene is attenuated in mice by arresting in the late liver stage. It also conferred complete protection in mice from challenge with wild type Plasmodium (Butler et al., 2011).
Related Vaccines(s)	Plasmodium FabB/FabF mutant vaccine
References

FabB/FabF