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guaB
Gene Name	guaB
Sequence Strain (Species/Organism)	Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
NCBI Gene ID	1254033
NCBI Protein GI	16765831
Locus Tag	STM2511
Genbank Accession	AE006468
Protein Accession	NP_461446
Taxonomy ID	700720
Gene Starting Position	2624451
Gene Ending Position	2625917
Gene Strand (Orientation)	-
Protein Name	inosine 5'-monophosphate dehydrogenase
Protein pI	6.59
Protein Weight	47186.87
Protein Length	488
Protein Note	catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate
DNA Sequence	>gi\|16763390:2624451-2625917 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 chromosome, complete genome ATCAGGAGCCCAGACGGTAGTTCGGGGACTCTTTGGTGATGGTCACGTCGTGAACGTGGCTTTCCTGAAT GCCCGCACCGCTGATACGCACAAACTCCGCTTTAGTACGCAGTTCGTCGATGGTAGCACAACCGGTCAGC CCCATACAGGAGCGCAGGCCGCCCATCTGCTGGTGAATGATCTCTTTCAGGCGACCTTTATAGGCTACGC GACCTTCGATACCTTCCGGCACCAGTTTGTCAGCGGCGTTGTCGCTCTGGAAGTAACGGTCGGAGGAACC TTTGGACATCGCACCCAGCGAGCCCATGCCGCGGTAAGATTTGTAAGAACGGCCCTGGTAGAGTTCGATT TCGCCCGGGGATTCTTCCGTACCCGCCAGCATGGAACCCACCATTACCGCGCTTGCACCTGCGGCAATCG CTTTGGCTATGTCGCCGGAGAAACGGATACCGCCGTCAGCGATAACCGGAATACCGGTACCTTCCAGCGC TTCAACTGCGTCAGAAACAGCGGTGATCTGCGGAACGCCCACGCCAGTCACGATACGAGTGGTACAGATG GAACCCGGGCCAATACCGACTTTCACCGCGCTGCAACCGGCTTCCGCCAGTGCGCGAGCGCCTGCGCCTG TCGCGACGTTGCCGCCGATGATTTGCAGGTCAGGATATTTAGCACGGGTTTCACGGATACGTTGCAACAC GCCTTCTGAATGACCGTGAGAGGAGTCGATCAGCAGTACGTCAACGCCTGCCGCCACCAGCGCGTCAACG CGCTCTTCGTTGCCCGCGCCTGCGCCGACCGCCGCGCCGACACGTAAACGGCCCTGCTCATCTTTGCAGG AGTTTGGTTTACGTTCCGCTTTCTGGAAATCTTTTACGGTAATCATGCCAAGCAGATGGAAGTTATCATC AACGACCAGCGCTTTTTCTACGCGTTTTTCGTGCATTTTTGCCAGCACGACTTCACGGGCTTCGCCTTCA CGAACGGTCACCAGACGCTCTTTCGGCGTCATGTAAACGCTAACCGGCTGGTTCAGGTCAGTCACAAAAC GCACGTCACGACCGGTGATGATACCCACCAGCTCGTTATCTTCAGTCACCACCGGATAGCCCGCAAAACC GTTACGCTCGGTCAGGGCTTTCACTTCATGCAACGTGGTGGTTGGCAGGACGGTCTGCGGGTCGGTCACT ACGCCGGACTCGTGTTTCTTCACGCGGCGAACTTCTTCCGCCTGGCGCTCAATGGACATGTTTTTGTGGA TAAAACCAATGCCGCCTTCCTGGGCCAGGGCAATTGCCAGGCGCGCTTCCGTCACGGTGTCCATCGCCGC AGAAAGCATAGGAATATTCAGACGAATAGTTTTCGTCAACTGCGTGCTGAGATCGGCAGTATTCGGCAAA ACGGTGGAGTGAGCGGGAACAAGGAGGACGTCGTCAAACGTCAGGGCTTCTTTAGCGATACGTAGCA
Protein Sequence	>gi\|16765831\|ref\|NP_461446.1\| inosine 5'-monophosphate dehydrogenase [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] MLRIAKEALTFDDVLLVPAHSTVLPNTADLSTQLTKTIRLNIPMLSAAMDTVTEARLAIALAQEGGIGFI HKNMSIERQAEEVRRVKKHESGVVTDPQTVLPTTTLHEVKALTERNGFAGYPVVTEDNELVGIITGRDVR FVTDLNQPVSVYMTPKERLVTVREGEAREVVLAKMHEKRVEKALVVDDNFHLLGMITVKDFQKAERKPNS CKDEQGRLRVGAAVGAGAGNEERVDALVAAGVDVLLIDSSHGHSEGVLQRIRETRAKYPDLQIIGGNVAT GAGARALAEAGCSAVKVGIGPGSICTTRIVTGVGVPQITAVSDAVEALEGTGIPVIADGGIRFSGDIAKA IAAGASAVMVGSMLAGTEESPGEIELYQGRSYKSYRGMGSLGAMSKGSSDRYFQSDNAADKLVPEGIEGR VAYKGRLKEIIHQQMGGLRSCMGLTGCATIDELRTKAEFVRISGAGIQESHVHDVTITKESPNYRLGS
Molecule Role	Virmugen
Molecule Role Annotation	A guaBA and clpP mutant (CVD 1921) of Salmonella Typhimurium is attenuated in mice after oral immunization. The mutant was also protective, rendering a vaccine efficacy of 86% in mice against challenge with wild type Salmonella Typhimurium (Tennant et al., 2011).
Related Vaccines(s)	Salmonella Typhimurium guaBA/clpP mutant vaccine , Salmonella Typhimurium guaBA/clpP/fliD mutant vaccine
References

guaB