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pmp10

Gene Name pmp10
Sequence Strain (Species/Organism) Chlamydophila pneumoniae
NCBI Protein GI CRI40334
Other Database IDs CDD:273587
CDD:284879
CDD:214872
Taxonomy ID 83558
Gene Strand (Orientation) ?
Protein Name Probable outer membrane protein pmp10
Protein pI 5.21
Protein Weight 93433.7
Protein Length 1016
Protein Note Chlamydial polymorphic outer membrane protein repeat; TIGR01376
Protein Sequence 
>CRI40334.1 Probable outer membrane protein pmp10 [Chlamydia pneumoniae]
MKSQFSWLVLSSTLACFTSCSTVFAATAENIGPSDSFDGSTNTGTYTPKNTTTGIDYTLTGDITLQNLGD
SAALTKGCFSDTTESLSFAGKGYSLSFLNIKSSAEGAALSVTTDKNLSLTGFSSLTFLAAPSSVITTPSG
KGAVKCGGDLTFDNNGTILFKQDYCEENGGAISTKNLSLKNSTGSISFEGNKSSATGKKGGAICATGTVD
ITNNTAPTLFSNNIAEAAGGAINSTGNCTITGNTSLVFSENSVTATAGNGGALSGDADVTISGNQSVTFS
GNQAVANGGAIYAKKLTLASGGGGGISFSNNIVQGTTAGNGGAISILAAGECSLSAEAGDITFNGNAIVA
TTPQTTKRNSIDIGSTAKITNLRAISGHSIFFYDPITANTAADSTDTLNLNKADAGNSTDYSGSIVFSGE
KLSEDEAKVADNLTSTLKQPVTLTAGNLVLKRGVTLDTKGFTQTAGSSVIMDAGTTLKASTEEVTLTGLS
IPVDSLGEGKKVVIAASAASKNVALSGPILLLDNQGNAYENHDLGKTQDFSFVQLSALGTATTTDVPAVP
TVATPTHYGYQGTWGMTWVDDTASTPKTKTATLAWTNTGYLPNPERQGPLVPNSLWGSFSDIQAIQGVIE
RSALTLCSDRGFWAAGVANFLDKDKKGEKRKYRHKSGGYAIGGAAQTCSENLISFAFCQLFGSDKDFLVA
KNHTDTYAGAFYIQHITECSGFIGCLLDKLPGSWSHKPLVLEGQLAYSHVSNDLKTKYTAYPEVKGSWGN
NAFNMMLGASSHSYPEYLHCFDTYAPYIKLNLTYIRQDSFSEKGTEGRSFDDSNLFNLSLPIGVKFEKFS
DCNDFSYDLTLSYVPDLIRNDPKCTTALVISGASWETYANNLARQALQVRAGSHYAFSPMFEVLGQFVFE
VRGSSRIYNVDLGGKFQF
Molecule Role Protective antigen
Molecule Role Annotation Four of the six in vitro neutralizing antigens (Pmp2, Pmp10, OmpH-like and enolase) could inhibit Cpn dissemination in a hamster model. The results show that these Cpn proteins are immunoaccessible in infectious EBs, and recommend further investigation on their value as vaccine components.(Finco et al., 2005)
References