VIOLIN: Vaccine Investigation and Online Information Network

major outer membrane protein
Gene Name	major outer membrane protein
Sequence Strain (Species/Organism)	Chlamydia trachomatis
NCBI Protein GI	AAA23141
Other Database IDs	CDD:279628
Taxonomy ID	813
Gene Strand (Orientation)	?
Protein Name	major outer membrane protein
Protein pI	5.08
Protein Weight	40217.17
Protein Length	468
Protein Note	Chlamydia major outer membrane protein; pfam01308
Protein Sequence	>AAA23141.1 major outer membrane protein [Chlamydia trachomatis] MKKLLKSVLVFAALSSASSLQALPVGNPAEPSLMIDGILWEGFGGDPCDPCTTWCDAISMRMGYYGDFVF DRVLKTDVNKEFQMGAAPTTRDVAGLEKDPVVNVARPNPAYGKHMQDAEMFTNAAYMALNIWDRFDVFCT LGATTGYLKGNSASFNLVGLFGTKTQSSGFDTANIVPNTALNQAVVELYTDTTFAWSVGARAALWECGCA TLGASFQYAQSKPKVEELNVLCNASEFTINKPKGYVGAEFPLDITAGTEAATGTKDASIDYHEWQASLAL SYRLNMFTPYIGVKWSRVSFDADTIRIAQPKLAKPVLDTTTLNPTIAGKGTVVSSAENELADTMQIVSLQ LNKMKSRKSCGIAVGTTIVDADKYAVTVETRLIDERAAHVNAQFRF
Molecule Role	Protective antigen
Molecule Role Annotation	Ct MOMP multi-epitope delivered by HBcAg could be an effective vaccine for the prevention of Ct. In this study, another two epitopes were selected from the MOMP protein and tandemly linked with MOMP370-387 to enhance the immunogenicity and the protective effect of the candidate vaccine.Both the immunogenicity and the protective effect of the tandem Ct MOMP multi-epitopes were much better than that of the single epitope. Therefore, vaccines based on the tandem Ct MOMP multi-epitopes could be more effective immune prophylactics to prevent Ct infection than the single epitope in murine model system.(Jiang et al., 2017)
References

major outer membrane protein