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htrA

Gene Name htrA
Sequence Strain (Species/Organism) Campylobacter jejuni
NCBI Protein GI CAA57948
Other Database IDs CDD:273938
CDD:290102
CDD:238487
GOA:Q46120
HSSP: 1KY9
InterPro: IPR001254
InterPro: IPR001478
InterPro: IPR001940
InterPro: IPR009003
InterPro: IPR011782
UniProtKB/TrEMBL: Q46120
Taxonomy ID 197
Protein Name serine protease
Protein pI 9.23
Protein Weight 48014.35
Protein Length 531
Protein Note periplasmic serine protease, Do/DeqQ family; TIGR02037
Protein Sequence 
>CAA57948.1 serine protease [Campylobacter jejuni]
MKKIFLSLSLASALFAASINFNESTATANRVNPAAGNAVLSYHDSIKDAKKSVVNISTSKTITRANRPSP
LDDFFNDPYFKQFFDFDFPQRKGKNDKEVVSSLGSGVIISKDGYIVTNNHVVDDADTITVNLPGSDIEYK
AKLIGKDPKTDLAVIKIEANNLSAITFTNSDDLMEGDVVFALGNPFGVGFSVTSGIISALNKDNIGLNQY
ENFIQTDASINPGNSGGALVDSRGYLVGINSAILSRGGGNNGIGFAIPSNMVKDIAKKLIEKGKIDRGFL
GASILALQGDTKKAYKNQEGALITDVQKGSSADEAGLKRGDLVTKVNDKVIKSPIDLKNYIGTLEIGQKI
SLSYERDGENKQASFILKGEKENPKGVQSDLIDGLSLRNLDPRLKDRLQIPKDVNGVLVDSVKEKSKGKN
SGFQEGDIIIGVGQSEIKNLKDLEQALKQVNKKEFTKVWVYRNGLATLLVLK
Molecule Role Virmugen
Molecule Role Annotation Moreover, ΔhtrA mutant infected mice displayed lower apoptotic cell numbers in the large intestinal mucosa, less colonic accumulation of neutrophils, macrophages and monocytes, lower large intestinal nitric oxide, IFN-γ, and IL-6 as well as lower TNF-α and IL-6 serum concentrations as compared to WT strain infected mice at day 6 p.i.(Heimesaat et al., 2014)
References