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apxIIIA

Gene Name apxIIIA
Sequence Strain (Species/Organism) Actinobacillus pleuropneumoniae
NCBI Protein GI CAA48711
Other Database IDs CDD:308152
CDD:225483
CDD:311996
GOA:P55131
InterPro: IPR001343
InterPro: IPR003995
InterPro: IPR011049
InterPro: IPR013550
InterPro: IPR018504
InterPro: IPR018511
UniProtKB/UniProt: P55131
Taxonomy ID 715
Protein Name ApxIIIA
Protein pI 5.56
Protein Weight 107581.37
Protein Length 1123
Protein Note RTX N-terminal domain; pfam02382
Protein Sequence 
>CAA48711.1 apxIIIA [Actinobacillus pleuropneumoniae]
MSTWSSMLADLKKRAEEAKRQAKKGYDVTKNGLQYGVSQAKLQALAAGKAVQKYGNKLVLVIPKEYDGSV
GNGFFDLVKAAEELGIQVKYVNRNELEVAHKSLGTADQFLGLTERGLTLFAPQLDQFLQKHSKISNVVGS
STGDAVSKLAKSQTIISGIQSVLGTVLAGINLNEAIISGGSELELAEAGVSLASELVSNIAKGTTTIDAF
TTQIQNFGKLVENAKGLGGVGRQLQNISGSALSKTGLGLDIISSLLSGVTASFALANKNASTSTKVAAGF
ELSNQVIGGITKAVSSYILAQRLAAGLSTTGPAAALIASSISLAISPLAFLRVADNFNRSKEIGEFAERF
KKLGYDGDKLLSEFYHEAGTIDASITTISTALSAIAAGTAAASAGALVGAPITLLVTGITGLISGILEFS
KQPMLDHVASKIGNKIDEWEKKYGKNYFENGYDARHKAFLEDSFSLLSSFNKQYETERAVLITQQRWDEY
IGELAGITGKGDKLSSGKAYVDYFQEGKLLEKKPDDFSKVVFDPTKGEIDISNSQTSTLLKFVTPLLTPG
TESRERTQTGKYEYITKLVVKGKDKWVVNGVKDKGAVYDYTNLIQHAHISSSVARGEEYREVRLVSHLGN
GNDKVFLAAGSAEIHAGEGHDVVYYDKTDTGLLVIDGTKATEQGRYSVTRELSGATKILREVIKNQKSAV
GKREETLEYRDYELTQSGNSNLKAHDELHSVEEIIGSNQRDEFKGSKFRDIFHGADGDDLLNGNDGDDIL
YGDKGNDELRGDNGNDQLYGGEGNDKLLGGNGNNYLSGGDGNDELQVLGNGFNVLRGGKGDDKLYGSSGS
DLLDGGEGNDYLEGGDGSDFYVYRSTSGNHTIYDQGKSSDLDKLYLSDFSFDRLLVEKVDDNLVLRSNES
SHNNGVLTIKDWFKEGNKYNHKIEQIVDKNGRKLTAENLGTYFKNAPKADNLLNYATKEDQNESNLSSLK
TELSKIITNAGNFGVAKQGNTGINTAALNNEVNKIISSANTFATSQLGGSGMGTLPSTNVNSMMLGNLAR
AA
Molecule Role Protective antigen
Molecule Role Annotation The splenic lymphocyte proliferation and the levels of IL-4, IL-6 and IL-12 of the inoculated mice were significantly increased, and the T- and B-cell populations were also elevated. Collectively, the candidate may efficiently induce the Th1- and Th2-type immune responses.(Hur et al., 2016)
Related Vaccines(s) mixture of Salmonella strains delivering ApxIA, ApxIIA, ApxIIIA and OmpA of A. pleuropneumoniae
References