VIOLIN: Vaccine Investigation and Online Information Network

PiuA
Gene Name	PiuA
NCBI Protein GI	WP_000724932
Other Database IDs	CDD:270428 CDD:278898
Taxonomy ID	1313
Gene Strand (Orientation)	?
Protein Name	amino acid ABC transporter substrate-binding protein
Protein pI	4.88
Protein Weight	29139.71
Protein Length	377
Protein Note	Substrate binding domain of an ABC transporter TcyJKLMN; the type 2 periplasmic binding protein fold; cd13710
Protein Sequence	>WP_000724932.1 amino acid ABC transporter substrate-binding protein [Streptococcus pneumoniae] MKKIVKYSSLAALALVAAGVLAACSGGAKKEGEAASKKEIIVATNGSPKPFIYEENGELTGYEIEVVRAI FKDSDKYDVKFEKTEWSGVFAGLDADRYNMAVNNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSL DDIGGKSTEVVQATTSAKQLEAYNAEHTDNPTILNYTKADLQQIMVRLSDGQFDYKIFDKIGVETVIKNQ GLDNLKVIELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
Molecule Role	Protective antigen
Molecule Role Annotation	Immunization with a combination of both PiuA and PiaA resulted in additive protection and was highly protective against systemic infection with S. pneumoniae.(Brown et al., 2001)
References