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IglC2
Gene Name	IglC2
Sequence Strain (Species/Organism)	Francisella tularensis subsp. tularensis SCHU S4
VO ID	VO_0011073
NCBI Gene ID	3191814
NCBI Protein GI	56708721
Locus Tag	FTT_1712c
Genbank Accession	AJ749949
Protein Accession	YP_170617
Taxonomy ID	177416
Gene Starting Position	1791972
Gene Ending Position	1792607
Gene Strand (Orientation)	-
Protein Name	intracellular growth locus subunit C
Protein pI	6.26
Protein Weight	21340.81
Protein Length	211
Protein Note	Similar to AAP58964.1 (Q7X3J5) IglC from Francisella novicida (23 kDa protein) (211 aa). BLAST Score = 405,Expect = e-112 Identities = 209/211 (99), Positives = 210/211 (99). Identical to FTT1357. It is part of the duplicated region 1767715..1801625 which is identical to 1374371..1408281
DNA Sequence	>NC_006570.2:1791972-1792607 Francisella tularensis subsp. tularensis SCHU S4 chromosome, complete genome ACTATGCAGCTGCAATATATCCTATTTTAGCAACTCCTTTATCTGTGCTAGCTGCGCAACATACTGGCAA ACTTCCTTGAGATGTTGTAAGACCATCTATAGATATAATATGATATCTCATTCCATCTTTTGAAACACCC ATAAGTTCTGTTGGCTCTATACTAATACTAAAAGCCTTAGCACTTATTGGATATAACTCTAAATTAGATA GATCTATCATAATACCCCATGCTTCATCAGTTTTATACTCTTGTTTTTTATTAGAATTACCTAACTTAAT TTTCATATCTGTAGCACTTGCTTGTAATATACTCGAAACTTTCTCTTCAATTTTAGTTCTAACATTTGAT TTAATTAGAACACCAAGAGTAATACTTATTGTTGGATTTATAGAGCCTGGCGTTATAGATAAACGTATTA CACTAGCAGCAGCTGTAGCCGAATCAGCTTTCGTGACATCCTCTCCACCATCTATAGCAACGATATTTTT ATCAAGTTTCTCCCCAGCTATAGTTAAAGAATCAATAAATAATCTACAATTAGGATGAGATCCTATACAT GCAGTAGGATCAGTTCTCACATGAATGGTCTCGCCACTTGTTACCTGTTGTCTTGTTATCATCTCACTCA TAATCA
Protein Sequence	>YP_170617.1 intracellular growth locus subunit C [Francisella tularensis subsp. tularensis SCHU S4] MIMSEMITRQQVTSGETIHVRTDPTACIGSHPNCRLFIDSLTIAGEKLDKNIVAIDGGEDVTKADSATAA ASVIRLSITPGSINPTISITLGVLIKSNVRTKIEEKVSSILQASATDMKIKLGNSNKKQEYKTDEAWGIM IDLSNLELYPISAKAFSISIEPTELMGVSKDGMRYHIISIDGLTTSQGSLPVCCAASTDKGVAKIGYIAA A
Molecule Role	Protective antigen
Molecule Role Annotation	Mice immunized with rLm/iglC were protected against lethal challenge with F. tularensis LVS administered by the intranasal route, a route chosen to mimic airborne infection, and, most importantly, against aerosol challenge with the highly virulent Type A F. tularensis SchuS4 strain (Jia et al., 2009).
Related Vaccines(s)	F. tularensis vaccine rLm/iglC
References

IglC2