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rpoS
Gene Name	rpoS
Sequence Strain (Species/Organism)	Salmonella enterica subsp. enterica serovar Typhimurium SL1344
NCBI Protein GI	301159483
Other Database IDs	CDD:180185 CDD:189414 CDD:146937 CDD:146934 CDD:100119 UniProtKB/TrEMBL: E1WAG8
Taxonomy ID	216597
Gene Strand (Orientation)	?
Protein Name	RNA polymerase sigma subunit RpoS (sigma-38)
Protein Length	330
Protein Note	RNA polymerase sigma factor RpoS; Validated
Protein Sequence	>gi\|301159483\|emb\|CBW19002.1\| RNA polymerase sigma subunit RpoS (sigma-38) [Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344] MSQNTLKVHDLNEDAEFDENGVEAFDEKALSEEEPSDNDLAEEELLSQGATQRVLDATQLYLGEIGYSPL LTAEEEVYFARRALRGDVASRRRMIESNLRLVVKIARRYGNRGLALLDLIEEGNLGLIRAVEKFDPERGF RFSTYATWWIRQTIERAIMNQTRTIRLPIHIVKELNVYLRTARELSHKLDHEPSAEEIAEQLDKPVDDVS RMLRLNERITSVDTPLGGDSEKALLDILADEKENGPEDTTQDDDMKQSIVKWLFELNAKQREVLARRFGL LGYEAATLEDVGREIGLTRERVRQIQVEGLRRLREILQTQGLNIEALFRE
Molecule Role	Virmugen
Molecule Role Annotation	Immunizations with Salmonella typhimurium rpoS and rpoS aroA mutants protected susceptible BALB/c mice against subsequent oral challenge with virulent S. typhimurium. When administered orally or intraperitoneally, rpoS derivatives of the mouse-virulent S. typhimurium strains, C52 and SL1344, were highly attenuated and were efficient single-dose live vaccines (Coynault et al., 1996).
Related Vaccines(s)	Salmonella Typhimurium rpoS mutant vaccine
References