VIOLIN: Vaccine Investigation and Online Information Network

CS1
Gene Name	CS1
Sequence Strain (Species/Organism)	Escherichia coli 536
VO ID	VO_0010941
NCBI Gene ID	4188469
NCBI Protein GI	110643341
Locus Tag	ECP_3188
Genbank Accession	CP000247
Protein Accession	YP_671071
Taxonomy ID	362663
Gene Starting Position	3361397
Gene Ending Position	3361897
Gene Strand (Orientation)	-
Protein Name	CS1 type fimbrial major subunit
Protein pI	8.86
Protein Weight	15880.12
Protein Length	166
Protein Note	CS1 type firmbrial major subunit; CS1 pili; coli surface antigen 1
DNA Sequence	>NC_008253.1:3361397-3361897 Escherichia coli 536, complete genome ATTAGAGAGCCTGGGACAGATAAATGCTAACTACGCCACGGTAGATACCCGTTTCCAGAACACCTTTGGT AGCCTGGGAAAACATCAGTGGTTTAGCCAGCGAACCGTTAGTTAACGCATCGGAAGCAAAGATTTTCGTT GCGGTAAACGTGGTTGCCGCATCAGCAGCAATCACTTCACCACCCCAGGTTACGGTCAGCGGAACAATTT TGCTGGCGTCCACGCTCTGAACCAGTTGCGCAGGCGAAACTAACTGCATTTTCACGTCTTTGGTCGTGTC ATTTGACCAGATTTTAGTCATTAACTGGTAAGATTGCAGACCCTGACCTGGCAGATATTGCATTTCTACT GCCTTCGGCAGTGCAGTATTATCGGTCTGCGTCATATCCAGAGCAGCATCAACGTTAGCAGTAACAGTGA TATCTTTTTGTACTGCTAATGCAGAACCTGCAACGGAAAACATTGCCGCTACCAGAAGAGATTTTGCGAA TACCTTTTTCA
Protein Sequence	>YP_671071.1 CS1 type fimbrial major subunit [Escherichia coli 536] MKKVFAKSLLVAAMFSVAGSALAVQKDITVTANVDAALDMTQTDNTALPKAVEMQYLPGQGLQSYQLMTK IWSNDTTKDVKMQLVSPAQLVQSVDASKIVPLTVTWGGEVIAADAATTFTATKIFASDALTNGSLAKPLM FSQATKGVLETGIYRGVVSIYLSQAL
Molecule Role	Protective antigen
Molecule Role Annotation	ETEC also expresses a range of colonisation factor antigens (CFAs), which allow adherence to the mucosal surface and therefore colonisation of the intestine. Some CFAs are sub-divided into coli surface (CS) antigens (Daley et al., 2007).
Related Vaccines(s)	EHEC O157 subunit vaccine using his-tagged N-terminal intimin , Live attenuated ETEC vaccine ACAM2017 , Shiga Toxin 2 B Subunit Vaccine
References

CS1