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guaA
Gene Name	guaA
Sequence Strain (Species/Organism)	Yersinia pestis KIM 10
NCBI Gene ID	1146310
NCBI Protein GI	22125262
Locus Tag	y1363
Genbank Accession	AE009952
Protein Accession	NP_668685
Taxonomy ID	187410
Gene Starting Position	1514988
Gene Ending Position	1516565
Gene Strand (Orientation)	+
Protein Name	GMP synthase
Protein pI	5.62
Protein Weight	53362.86
Protein Length	525
Protein Note	contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway
DNA Sequence	>gi\|22123922:1514988-1516565 Yersinia pestis KIM 10 chromosome, complete genome CATGACAAAAAATATCCATAAGCATCGCATCCTTATTCTTGATTTCGGCTCGCAGTACACCCAATTATTG GCGCGTCGTGTGCGTGAGATTGGTGTCTATTGTGAACTATGGGCATGGGATGTCACCGAAGCCCAAATCC GTGAATTTAATCCAAGTGGTATCATCCTCTCTGGTAGCCCTGAAAGTACGATAGAAAACGGTAGCCCGCG CGCACCAGACTATGTGTTTACGGCTGGTGTACCGGTGTTGGGTGTGTGCTATGGCATGCAGACCATGGCG ATACAATTGGGCGGTAAAGTTGAGAGTTCAAATCAGCGTGAATTTGGTTATGCGCAAGTTGAAATTAAAG CTGACAGCGCGCTGATCCGTGATATCAAAGATGCCATCAATCCGGCAGGCGAAGCCGTATTGGATGTTTG GATGAGTCACGGTGACAAAGTTGCGGAGATCCCTGCTGATTTTGTCACGGTTGCCAGCACGGATACCTGT CCGTTTGCCATTATGGCTAACGAAGAAAAACGTTTTTATGGTGTCCAGTTCCATCCTGAAGTGACACACA CCAAGCAAGGCCTGCGTTTGTTGGAGCGTTTCGTGCTGGGTATCTGTGGCTGCGAAGCGCTATGGACATC TGCCACCATTATCGAAGATGCAATTGTCCGTTTGCGTGAGCAAATCGGCGACGATCATGTGATCTTGGGG TTAAGTGGCGGTGTCGACTCTTCAGTGACGGCCATGTTGTTGCACCGCGCTATCGGTAAACGCCTGACCT GTGTATTCGTGGATAACGGCCTATTACGCTTAAACGAAGCAGATCAGGTCTTGGAAATGTTTGGCGATAA ATTTGGCCTGAATATTGTCCATGTGGCGGCAGAGGATCGCTTCCTTTCGGCACTGACGGGAGTGGACGAA CCAGAAGCGAAACGTAAAATCATTGGCCGTGTCTTTGTCGAACTCTTCGACGAAGAAGCCTGTAAACAAG AGCAGGTGAAATGGTTGGCACAGGGTACGATTTACCCTGATGTGATCGAATCGGCTGCATCAGCTACCGG TAAAGCGCATGTGATTAAATCTCACCACAATGTGGGCGGTTTGCCAAAAGAGATGAAGCTGGGCCTGGTT GAGCCGCTGAAAGAGCTGTTTAAAGATGAAGTGCGCAAGATTGGTCTGGAGCTTGGCTTGCCATACGACA TGCTGTACCGCCATCCTTTCCCAGGGCCGGGCTTAGGTGTGCGCGTATTGGGCGAAGTGAAGAAAGAGTA TTGCGATTTGCTGCGCCGTGCTGACGCTATCTTTATTGAAGAGCTGCACAAAGCTGATTTGTACAATAAA GTTAGCCAGGCTTTCACTGTCTTCCTGCCAGTACGTTCAGTCGGTGTGATGGGTGATGGCCGTAAATATG ATTGGGTTGTCTCTCTGCGTGCGGTAGAGACGGTTGATTTCATGACTGCACATTGGGCACATCTGCCATA CGACTTCCTTGGCCGCGTTTCAAACCGCATCATTAATGAAGTCAATGGTATCTCGCGCGTAGTTTATGAT ATCAGCGGCAAGCCACCTGCAACGATTGAGTGGGAATG
Protein Sequence	>gi\|22125262\|ref\|NP_668685.1\| GMP synthase [Yersinia pestis KIM 10] MTKNIHKHRILILDFGSQYTQLLARRVREIGVYCELWAWDVTEAQIREFNPSGIILSGSPESTIENGSPR APDYVFTAGVPVLGVCYGMQTMAIQLGGKVESSNQREFGYAQVEIKADSALIRDIKDAINPAGEAVLDVW MSHGDKVAEIPADFVTVASTDTCPFAIMANEEKRFYGVQFHPEVTHTKQGLRLLERFVLGICGCEALWTS ATIIEDAIVRLREQIGDDHVILGLSGGVDSSVTAMLLHRAIGKRLTCVFVDNGLLRLNEADQVLEMFGDK FGLNIVHVAAEDRFLSALTGVDEPEAKRKIIGRVFVELFDEEACKQEQVKWLAQGTIYPDVIESAASATG KAHVIKSHHNVGGLPKEMKLGLVEPLKELFKDEVRKIGLELGLPYDMLYRHPFPGPGLGVRVLGEVKKEY CDLLRRADAIFIEELHKADLYNKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETVDFMTAHWAHLPY DFLGRVSNRIINEVNGISRVVYDISGKPPATIEWE
Molecule Role	Virmugen
Molecule Role Annotation	A guaBA mutant is attenuated in mice and induced significant protection from challenge with wild type Y. pestis (Oyston et al., 2010).
Related Vaccines(s)	Yersinia pestis guaBA mutant vaccine
References

guaA