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aroA

Gene Name aroA
Sequence Strain (Species/Organism) Yersinia enterocolitica subsp. enterocolitica 8081
NCBI Gene ID 4713234
NCBI Protein GI 123441850
Locus Tag YE1538
Genbank Accession AM286415
Protein Accession YP_001005833
Taxonomy ID 393305
Gene Starting Position 1726120
Gene Ending Position 1727406
Gene Strand (Orientation) +
Protein Name 3-phosphoshikimate 1-carboxyvinyltransferase
Protein pI 5.16
Protein Weight 43855.83
Protein Length 428
Protein Note catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis
DNA Sequence 
>gi|123440403:1726120-1727406 Yersinia enterocolitica subsp. enterocolitica 8081, complete genome
CATGCTGGAATCCCTGACTTTACACCCCATTGCCCTGATTAATGGCACTGTTAATTTACCCGGTTCTAAA
AGTGTTTCTAACCGTGCACTTCTTCTGGCAGCGCTGGCCGAGGGGACAACTCAGCTGAATAACTTGTTAG
ACAGTGATGACATTCGCCATATGCTTAATGCTCTACAGGCATTGGGGGTGAAATATCGCCTGTCTGCTGA
TCGTACCCGCTGTGAGGTTGATGGATTGGGCGGCAAATTGGTTGCTGAACAGCCATTAGAATTGTTTTTG
GGTAATGCCGGCACGGCCATGCGCCCATTGGCTGCGGCACTGTGCCTGGGGAAAAATGACATTGTATTGA
CCGGCGAACCACGCATGAAAGAGCGGCCAATTGGTCATTTGGTTGATGCATTGCGTCAGGGCGGAGCACA
GATTGATTATCTGGAGCAAGAAAACTACCCGCCGTTGCGCATACGCGGGGGCTTTCGTGGCGGTAAACTC
ACCGTAGACGGCAGTGTTTCCAGTCAATTCCTCACGGCACTTTTGATGACCGCTCCCTTAGCTGAACAAG
ATACTGAAATTCAGATCCAAGGGGAGTTGGTGTCTAAGCCTTATATCGACATTACGTTGCATCTGATGAA
AGCCTTCGGTGTGGATGTCGTTCATGAAAATTATCAGATTTTTCATATTAAAGGCGGGCAGACTTACCGC
TCACCAGGTATCTATCTGGTTGAAGGTGATGCGTCTTCTGCATCTTATTTCCTCGCCGCAGCTGCTATCA
AAGGTGGAACAGTCCGCGTAACCGGCATTGGTAAACAAAGTGTACAAGGTGATACCAAGTTTGCTGATGT
ACTGGAGAAAATGGGCGCTAAAATCAGTTGGGGTGATGATTATATCGAGTGCAGCCGTGGTGAATTACAG
GGTATCGATATGGATATGAACCATATTCCTGATGCTGCAATGACCATTGCTACCACCGCACTGTTTGCCG
ACGGCCCGACTGTTATTCGTAATATCTATAACTGGCGAGTGAAGGAAACCGACCGCTTATCCGCGATGGC
GACTGAATTGAGAAAAGTGGGCGCGGAAGTGGAAGAGGGGCAAGACTACATTCGGGTGGTGCCCCCTGCG
CAGCTAATCGCAGCCGAAATAGGGACTTATAATGACCACCGCATGGCGATGTGTTTCTCGCTGGTGGCTT
TATCTGACACGCCGGTGACTATCCTTGATCCGAAATGTACCGCGAAAACATTCCCTGACTACTTTGAACA
ACTGGCCCGATTGAGCCAGATAGCCTA
Protein Sequence 
>gi|123441850|ref|YP_001005833.1| 3-phosphoshikimate 1-carboxyvinyltransferase [Yersinia enterocolitica subsp. enterocolitica 8081]
MLESLTLHPIALINGTVNLPGSKSVSNRALLLAALAEGTTQLNNLLDSDDIRHMLNALQALGVKYRLSAD
RTRCEVDGLGGKLVAEQPLELFLGNAGTAMRPLAAALCLGKNDIVLTGEPRMKERPIGHLVDALRQGGAQ
IDYLEQENYPPLRIRGGFRGGKLTVDGSVSSQFLTALLMTAPLAEQDTEIQIQGELVSKPYIDITLHLMK
AFGVDVVHENYQIFHIKGGQTYRSPGIYLVEGDASSASYFLAAAAIKGGTVRVTGIGKQSVQGDTKFADV
LEKMGAKISWGDDYIECSRGELQGIDMDMNHIPDAAMTIATTALFADGPTVIRNIYNWRVKETDRLSAMA
TELRKVGAEVEEGQDYIRVVPPAQLIAAEIGTYNDHRMAMCFSLVALSDTPVTILDPKCTAKTFPDYFEQ
LARLSQIA
Molecule Role Virmugen
Molecule Role Annotation An aroA mutant is highly attenuated in mice, and after 3 doses induces significant protection from challenge with wild type Y. enterocolitica (Bowe et al., 1989).
Related Vaccines(s) Yersinia enterocolitica aroA mutant vaccine
References