VIOLIN Logo
VO Banner
Search: for Help
About
Introduction
Statistics
VIOLIN News
Your VIOLIN
Register or Login
Submission
Tutorial
Vaccine & Components
Vaxquery
Vaxgen
VBLAST
Protegen
VirmugenDB
DNAVaxDB
CanVaxKB
Vaxjo
Vaxvec
Vevax
Huvax
Cov19VaxKB
Host Responses
VaximmutorDB
VIGET
Vaxafe
Vaxar
Vaxism
Vaccine Literature
VO-SciMiner
Litesearch
Vaxmesh
Vaxlert
Vaccine Design
Vaxign2
Vaxign
Community Efforts
Vaccine Ontology
ICoVax 2012
ICoVax 2013
Advisory Committee
Vaccine Society
Vaxperts
VaxPub
VaxCom
VaxLaw
VaxMedia
VaxMeet
VaxFund
VaxCareer
Data Exchange
V-Utilities
VIOLINML
Help & Documents
Publications
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UM Logo

guaA

Gene Name guaA
Sequence Strain (Species/Organism) Francisella tularensis subsp. holarctica LVS
NCBI Gene ID 3951701
NCBI Protein GI 89256406
Locus Tag FTL_1071
Genbank Accession AM233362
Protein Accession YP_513768
Taxonomy ID 376619
Gene Starting Position 1023478
Gene Ending Position 1025028
Gene Strand (Orientation) ?
Protein Name GMP synthase
Protein pI 6.04
Protein Weight 52837.22
Protein Length 516
Protein Note contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway
DNA Sequence 
>gi|89255449:1023478-1025028 Francisella tularensis subsp. holarctica LVS chromosome, complete genome
AATGACAGATATACATAATCATAAGATTTTGATTTTAGATTTTGGCTCGCAATATACACAACTTATTGCT
CGTAGAGTAAGAGAAGTAGGTGTTTTTTGTGAAATTTTCCCTCATGATGTAGCAGCTGATTTTATCAAAA
ATTATCAAGCAAAAGGAATAATTTTATCAGGTGGTCCTGAGTCAGTTTATGATTCTGATGTCAAAGCTCC
TGAGATAGTTTTTGAGCTTGGAGTACCTGTTTTGGGTATTTGTTATGGCATGCAAACAATGGTAATGCAG
CATGGTGGCGAAGTAAAAGGAGCTGATCAAAGTGAATTTGGTAAGGCAATTATAAATATCCTAAATTTAA
CAAATAACATATTTTCAAATATGGAGCATGAGCAGCTAGTTTGGATGAGTCATAGTGACAAAGTCACTCA
AACTGGTGAGCATTTTGAGATAATTGCTTCTTCAACAAATGCTCCAGTTGCGGCAGTTGCACATAAAAAT
AAGCCTTTTTTTGGTGTGCAGTTTCACCCAGAAACTACTCATACAGAAAATGGTAAGCAAATTATTGAGA
ATTTTGTCGTTAATATCTGCGGATGTGATACTCTGTGGAATATCGAAAACATTATCGAAAATGATATAAA
AGAAATTAAACAAAAAGTTGGTACTGATAAAGTAATTTTAGGGCTATCTGGAGGTGTTGATTCATCTGTT
GTAGCTGCGATATTACATCAAGCTATCGGCGATCAGCTAACTTGTATATTTGTAGATACTGGTTTACTGC
GCCTTAATGAGGGTGATCAAGTTATGCAAGTATTTGCAGAGCATATGGATATTAATGTTATTCGTATCAA
TGCAAAAAATAGATTCTTAGATGCCCTAAGGGGTATCTGTGATCCAGAACAAAAACGTAAAATTATCGGT
AAGCTATTTGTTGATATTTTTGATGAAGAGGCTGCTAAGATAGAGAATGCTAAATGGCTTGCGCAGGGCA
CTATCTACAGTGATGTAATTGAATCAGCTAGCAATAATCAGTCTAAAGCACATGTAATTAAATCACATCA
TAATGTTGGTGGCTTACCAAAAGAAATGAAACTTAAGCTTTTAGAACCATTAAGAGAGCTTTTCAAAGAT
GAGGTTCGTAAATTAGGCTTAGGTTTAGGATTACCTTATAATATGCTTTATAGACATCCATTTCCTGGTC
CTGGTCTTGGAGTACGTATATTAGGTGAAATAAAGAAAGAGTATGTAGAAACGTTACAAAAAGCTGATGC
TATATTTACAGAAGAGCTTTATAAACATAATTTATACCATGATGTTTCTCAAGCTTTTGGGGTGTTTTTA
CCTATCAAATCGGTAGGTGTAGTTGGTGATCAGCGTAGATATGAGTATGTAATAGCTCTAAGAGCTGTCG
TTAGTATCGATTTTATGACTGCAACGTGGGCTAATTTACCTTATGATTTTCTGTCACTAGTTTCAAATAG
AATTGTAAATGAAGTAAAACAAGTATCAAGAGTTGTGTATGATGTGACAGGAAAACCACCTGGAACAATT
GAATGGGAATA
Protein Sequence 
>gi|89256406|ref|YP_513768.1| GMP synthase [Francisella tularensis subsp. holarctica LVS]
MTDIHNHKILILDFGSQYTQLIARRVREVGVFCEIFPHDVAADFIKNYQAKGIILSGGPESVYDSDVKAP
EIVFELGVPVLGICYGMQTMVMQHGGEVKGADQSEFGKAIINILNLTNNIFSNMEHEQLVWMSHSDKVTQ
TGEHFEIIASSTNAPVAAVAHKNKPFFGVQFHPETTHTENGKQIIENFVVNICGCDTLWNIENIIENDIK
EIKQKVGTDKVILGLSGGVDSSVVAAILHQAIGDQLTCIFVDTGLLRLNEGDQVMQVFAEHMDINVIRIN
AKNRFLDALRGICDPEQKRKIIGKLFVDIFDEEAAKIENAKWLAQGTIYSDVIESASNNQSKAHVIKSHH
NVGGLPKEMKLKLLEPLRELFKDEVRKLGLGLGLPYNMLYRHPFPGPGLGVRILGEIKKEYVETLQKADA
IFTEELYKHNLYHDVSQAFGVFLPIKSVGVVGDQRRYEYVIALRAVVSIDFMTATWANLPYDFLSLVSNR
IVNEVKQVSRVVYDVTGKPPGTIEWE
Molecule Role Virmugen
Molecule Role Annotation A guaA mutant is highly attenuated in mice and induces significant protection from challenge with parent strain F. tularensis LVS (Santiago et al., 2009).
Related Vaccines(s) Francisella tularensis guaA mutant vaccine
References