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purM

Gene Name purM
Sequence Strain (Species/Organism) Burkholderia pseudomallei K96243
NCBI Gene ID 3092877
NCBI Protein GI 53720427
Locus Tag BPSL2818
Genbank Accession BX571965
Protein Accession YP_109413
Taxonomy ID 272560
Chromosome No 1
Gene Starting Position 3369942
Gene Ending Position 3370997
Gene Strand (Orientation) -
Protein Name phosphoribosylaminoimidazole synthetase
Protein pI 4.98
Protein Weight 33766.88
Protein Length 351
Protein Note Also known as purGcatalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis
DNA Sequence 
>gi|53717639:3369942-3370997 Burkholderia pseudomallei K96243 chromosome chromosome 1, complete sequence
GTCAGACCACGACCGTCTGCGCCTCGCCTTCGCGGCTCGCGCGCACGGTGCCGATCTTCCATACCTGCTC
GCCCGCGTCGGCCAGTTGGCGGAGCGCGTCGTCCGCGTCGGCGGCCGACACGATCACGGCCATCCCGATC
CCGCAGTTGAACACGCGGTGCATCTCCGCATCGGCGACGCCGCCGTGCTGCCGCAGCCACTGGAACAGCG
GCGGCAGCGGCCATGCGTGCTGGTCGAGTTCGGCCGTGAGGCCGTCGCGCAGCACGCGCGGAATGTTCTC
GACGAGGCCGCCGCCCGTGATGTGCGCCATTCCCTTCACCGCGATCTTCTCCATCAGCGCGAGGAGCGGC
TTCACGTAGATGCGCGTCGGCGCCATCAGCGCGTCGGCGAGCGAGCGGCCGTGGAAATCGGCCGACAGGT
CCGGATTCGCGCGCTCGATGATCTTGCGCACGAGCGAGAAACCGTTCGAATGGATGCCGCTCGACGCGAG
GCCCAGCACGACGTCGCCCTCGGCGATCGTGCTGCCGTCAATGATCTTGCTCTTCTCGACCGCGCCGACC
GCGAAGCCCGCCAGATCGTATTCGCCGTCCGGGTACATGCCCGGCATCTCGGCCGTCTCGCCGCCGATCA
GCGCGCAGCCCGCCAGCTCGCAGCCCGTCGCGATGCCCTTGACGACGGTCGCGGCCGTCTCGACGTCGAG
CTTGCCGCACGCGAAGTAGTCGAGGAAGAACAGCGGCTCGGCGCCCTGCACGAGAATGTCGTTTACGCTC
ATCGCGACGAGATCCTGGCCGACCGTATCGTGTTTGTTCAGATGAAACGCGAGCTTGAGCTTCGTGCCGA
CGCCGTCCGTGCCCGATACGAGCACGGGCTCCCGGTACTTCTTCGGCACCTCGAACAGCGCGCCGAACCC
GCCGATGCCGCCGAGCACGCCGTCGCGCAGCGTTTTCTTCGCAAAGGGCTTGATCTTGTCGACGAGCGCG
TCGCCCGCGTCGATGTCGACGCCCGCGTCACGGTAGGACAGGCCCTGGGCGTCGGGAGCGGATTTCGGAG
GATTCA
Protein Sequence 
>gi|53720427|ref|YP_109413.1| phosphoribosylaminoimidazole synthetase [Burkholderia pseudomallei K96243]
MNPPKSAPDAQGLSYRDAGVDIDAGDALVDKIKPFAKKTLRDGVLGGIGGFGALFEVPKKYREPVLVSGT
DGVGTKLKLAFHLNKHDTVGQDLVAMSVNDILVQGAEPLFFLDYFACGKLDVETAATVVKGIATGCELAG
CALIGGETAEMPGMYPDGEYDLAGFAVGAVEKSKIIDGSTIAEGDVVLGLASSGIHSNGFSLVRKIIERA
NPDLSADFHGRSLADALMAPTRIYVKPLLALMEKIAVKGMAHITGGGLVENIPRVLRDGLTAELDQHAWP
LPPLFQWLRQHGGVADAEMHRVFNCGIGMAVIVSAADADDALRQLADAGEQVWKIGTVRASREGEAQTVV
V
Molecule Role Virmugen
Molecule Role Annotation Mice that were challenged with a higher dose of mutant 56:65 purM were protected (Breitbach et al., 2008).
Related Vaccines(s) Burkholderia pseudomallei purM mutant vaccine
References