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apxIIID

Gene Name apxIIID
Sequence Strain (Species/Organism) Actinobacillus pleuropneumoniae serovar 2
NCBI Nucleotide GI 470687
Other Database IDs CDD:130902
Taxonomy ID 34063
Gene Strand (Orientation) ?
Protein Name RTX toxin
Protein Note type I secretion membrane fusion protein, HlyD family; TIGR01843
DNA Sequence 
>gb|L12145.1|ACNNON:6090-7523 Actinobacillus pleuropneumoniae (serotype 2) RTX toxin III (apxIII CABD) genes, complete cds
ATGAAGTTATGGATTCTAGGACTTGGGGAATTTTTTCAACGTTATCGTAATATTTGGCGTGAAATATGGA
AAATCCGCAAACAATTAGATACCCCAGCAAGACAAAAAGATGAAAACGAATTTTTGCCTCGGCATTTAGA
GTTAATTGAGACACCTATTTCAAAAAAGCCACGGCTGATCGCTTATTTGATAATGCTATTTCTATTTTTA
GCTATTGTAATTTCCATTATTAGTAAAGTAGAAATTGTTGCTAGTGCTACAGGTAAGTTGGTATTTAGTG
GACATAGTAAAGAAATAAAGCCTATTGAGAATGCTTTAGTAAAAGACATTTTTGTTAAAGATGGACAATT
TGTTGAAAAAGGACAATTATTATTAAATCTCACCGCACTTGGCTGCGATGCAGACAAACAAAAAACTAAA
GTATCGTTAGGATTGGAAAGATTAGATGGTTACCGATATAAGTCATTGTTATATAGCATTGAACACAATA
GATTACCTTTATTGGATTTTAACCAAGCTGATTTTGATTCTGTTCAGGAAGAAGATAAGACTGGCGCACG
TCATTTAATTACCGAACAATTTGAGACTTGGCAAAAACAAAAATATCAGAAGGAATTAGCGTATCAACGT
AAACAAGCTGAAAAACAAACAGTATTAGCAAATATCCGTAAATATGAAAGCGCTAGTCGTATTGAAAAGG
AGAAATTAAGTGATTTAAAAAAATTATATGATGTAAAGTCTATTTCTAAGCATGAGTTGTTAGCACAAGA
AAATAGATATGTTGAAGCTAGTAATGAATTGTCTGTTTATCAATCTCATCTCAAAGAAGTAGAAAGTGAC
TTGCTTAAAGCACAAGAAGATTTAAAGCTTGTTACTCAATTATTTAAGAGTGATATTTTGGAAAAACTAC
AGCAAAATATACAACGCGAAAAGCAGCTCACTTTAGAACTTGAGAAAAATGAACAACGTCAATTAGCCTC
TATCATTAGGGCGCCAGTATCAGGCACAGTCCAACAATTAAAAACTCATACTAAAGGTGGCGTAGTAACT
ACTGCAGAAACCTTAATGGTCATTGCTCCTGAGGATGACGTGTTGGAAGTAAGTGCTTTAATTCAAAACA
AAGATGTTGGTTTTGTTGAAATTGGACAGGAAGCAGTTATTAAAGTGGAAACTTTTCCCTACACAAGATA
TGGTTATCTCTATGGAAAAGTAAAAACTATTACTCTTGATGCTATTGAGCACCCTCAGCTTGGTTTAGTT
TTCAATTCTATTATTGAGATTAACAAGAAAACATTAACAGATGGTGATAAAGAAATTCAATTAGGTTCTG
GAATGAGCGTTATTGCAGAAATTAAAACAGGAGAACGCAGTGTTATCAGTTTCCTACTCAGTCCATTAGA
AGAATCTATTACTGAAAGTCTAAGAGAACGTTAA
Molecule Role Virmugen
Molecule Role Annotation An apxIIID mutant, in combination with an apxIIIB mutation, is highly attenuated in pigs and induces significant protection from challenge with wild type A. pleuropneumoniae. The mutant also was slightly attenuated in mice and induced protection in mice against challenge from the parent strain (Park et al., 2009).
Related Vaccines(s) Actinobacillus pleuropneumoniae apxIIIB and apxIIID double mutant vaccine
References