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Vaxgen Search

Found 42 gene(s).

Gene ID Gene Name Sequence Strain (Species/Organism) VO ID NCBI Gene ID NCBI Nucleotide GI NCBI Protein GI Locus Tag Genbank Accession Protein Accession 3D structure: PDB ID Other Database IDs Protein Name Molecule Role Vaccines Involving this Gene
118 Ag85B from M. tuberculosis H37Rv Mycobacterium tuberculosis H37Rv VO_0012364 885785 15609023 Rv1886c AL123456 NP_216402 EMBL: AE000516
EMBL: AF198032
EMBL: BX842578
EMBL: U38939
EMBL: X62398
GenomeReviews: AE000516_GR
GenomeReviews: AL123456_GR
InterPro: IPR000801
KEGG: mtc:MT1934
KEGG: mtu:Rv1886c
PDB: 1F0N
PDB: 1F0P
Pfam: PF00756
PIR: C70516
TIGR: MT1934
TubercuList: Rv1886c
UniProt: P31952
diacylglycerol acyltransferase/mycolyltransferase Ag85B Protective antigen
  • Arabinomannan-tetanus toxoid conjugate
  • Ag85B and ESAT-6 fusion protein
  • M. tuberculosis DNA Vaccine encoding Ag85B Protein
  • MVA/IL-15/5Mtb vaccine
  • M. tuberculosis DNA vaccine encoding Ag85B, MPT64 and MPT83
  • rBCG-Ag85A/ Ag85B
  • LT-BCG- Ag85B /Rv3425
  • 588 Apa Mycobacterium tuberculosis H37Rv VO_0011175 885896 57116926 Rv1860 AL123456 YP_177849 hypothetical protein Protective antigen
  • M. tuberculosis DNA Vaccine APADNA priming and APAMVA boosting
  • 1829 bfrA Mycobacterium tuberculosis H37Rv 885767 15609013 Rv1876 AL123456 NP_216392 bacterioferritin BfrA Protective antigen
  • BCG-DHTM
  • 866 DnaK Mycobacterium tuberculosis H37Rv VO_0012408 885946 15607491 Rv0350 AL123456 NP_214864 chaperone protein DnaK Protective antigen
  • BCG-DHTM
  • 909 drrC Mycobacterium tuberculosis H37Rv 888491 15610075 Rv2938 BX842581 NP_217454 daunorubicin-DIM-transport integral membrane protein ABC transporter DrrC Virmugen
  • Mycobacterium tuberculosis drrC mutant vaccine
  • 104 EsxA (ESAT-6) Mycobacterium tuberculosis H37Rv VO_0010919 886209 57117165 Rv3875 AL123456 YP_178023 EMBL: AE000516
    EMBL: AF004671
    EMBL: AF420491
    EMBL: BX842584
    EMBL: X79562
    GenomeReviews: AE000516_GR
    GenomeReviews: AL123456_GR
    InterPro: IPR010310
    KEGG: mtc:MT3989
    KEGG: mtu:Rv3875
    PDB: 1WA8
    Pfam: PF06013
    PIR: A70803
    TIGR: MT3989
    TubercuList: Rv3875
    UniProt: P0A564
    ESAT-6 protein EsxA Protective antigen
  • recombinant S. typhimurium secreting M. tuberculosis ESAT-6
  • Ag85B and ESAT-6 fusion protein
  • MVA/IL-15/5Mtb vaccine
  • 121 EsxB Mycobacterium tuberculosis H37Rv VO_0010951 886194 15611010 Rv3874 AF004671 NP_218391 3FAV EMBL: AE000516
    EMBL: AF004671
    EMBL: AF419854
    EMBL: BX842584
    GenomeReviews: AE000516_GR
    GenomeReviews: AL123456_GR
    InterPro: IPR010310
    KEGG: mtc:MT3988
    KEGG: mtu:Rv3874
    Pfam: PF06013
    PIR: H70802
    SMR: P0A566
    TIGR: MT3988
    TubercuList: Rv3874
    UniProt: P0A566
    ESAT-6-like protein EsxB Protective antigen
    4396 esxV Mycobacterium tuberculosis H37Rv NP_218136 CDD:310537 ESAT-6 like protein EsxV Protective antigen
  • ID93/GLA-SE
  • 4397 esxW Mycobacterium tuberculosis H37Rv NP_218137 CDD:310537 ESAT-6 like protein EsxW Protective antigen
  • ID93/GLA-SE
  • 906 fadD26 Mycobacterium tuberculosis H37Rv 887603 57117038 Rv2930 BX842581 NP_217446 acyl-CoA synthetase Virmugen
  • Mycobacterium tuberculosis fadD26 mutant vaccine
  • 122 FbpA (Ag85A) Mycobacterium tuberculosis H37Rv VO_0010952 886132 15610940 Rv3804c AL123456 NP_218321 1SFR EMBL: AE000516
    EMBL: BX842584
    EMBL: M27016
    EMBL: U47335
    GenomeReviews: AE000516_GR
    GenomeReviews: AL123456_GR
    InterPro: IPR000801
    KEGG: mtc:MT3911
    KEGG: mtu:Rv3804c
    PDB: 1SFR
    Pfam: PF00756
    PIR: H70887
    TIGR: MT3911
    TubercuList: Rv3804c
    UniProt: P0A4V2
    diacylglycerol acyltransferase/mycolyltransferase Ag85A Protective antigen
  • MVA85A prime and BCG boost
  • rBCG-Ag85A[Tokyo]
  • DNA vaccine co-expressing A85A and caspase-3
  • MVA/IL-15/5Mtb vaccine
  • M. tuberculosis DNA vaccine pcDNA3.1+/Ag85A DNA encoding Ag85A
  • M. tuberculosis DNA vaccine DNAAg85A encoding a single immunogenic M.tb Ag
  • rBCG-Ag85A/ Ag85B
  • 814 FbpD Mycobacterium bovis BCG str. Tokyo 172 VO_0012366 7562680 224992215 JTY_3867 AP010918 YP_002646905 1R88 MPT51/MPB51 antigen protein Protective antigen
    821 HBHA Mycobacterium tuberculosis H37Ra VO_0012373 5211814 148660242 MRA_0482 CP000611 YP_001281765 iron-regulated heparin binding hemagglutinin Hbha Protective antigen
  • M. tuberculosis HBHA Protein Vaccine
  • 817 KatG Mycobacterium tuberculosis H37Rv VO_0012369 885638 15609045 Rv1908c AL123456 NP_216424 1SJ2 catalase-peroxidase Protective antigen
  • M. tuberculosis DNA Vaccine encoding KatG
  • M. tuberculosis DNA vaccine (containing the ESAT-6, MPT-64, MPT-83, and KatG constructs)
  • 951 leuD Mycobacterium tuberculosis H37Rv 888225 15610124 Rv2987c BX842581 NP_217503 3H5J isopropylmalate isomerase small subunit Virmugen
  • Mycobacterium tuberculosis leuD mutant vaccine
  • 952 lysA Mycobacterium tuberculosis H37Rv 886960 15608433 Rv1293 BX842576 NP_215809 1HKW diaminopimelate decarboxylase LysA Virmugen
  • Mycobacterium tuberculosis lysA/secA2 mutant vaccine
  • 991 mce-2 Mycobacterium tuberculosis CDC1551 925014 15839991 MT0618 AE000516 NP_335028 virulence factor Virmugen
  • Mycobacterium tuberculosis mce-2 mutant vaccine
  • 992 mce-3 Mycobacterium tuberculosis CDC1551 923491 15841441 MT2018 AE000516 NP_336478 virulence factor Virmugen
  • Mycobacterium tuberculosis mce-2 mutant vaccine
  • Mycobacterium tuberculosis mce-3 mutant vaccine
  • 589 Mpt63 Mycobacterium tuberculosis H37Rv VO_0011176 885334 15609063 Rv1926c AL123456 NP_216442 1LMI immunogenic protein Mpt63 Protective antigen
    815 MPT64 Mycobacterium tuberculosis H37Rv VO_0012367 885925 15609117 Rv1980c A42312 NP_216496 2HHI immunogenic protein Mpt64 Protective antigen
  • M. tuberculosis DNA vaccine encoding Ag85B, MPT64 and MPT83
  • M. tuberculosis DNA vaccine (containing the ESAT-6, MPT-64, MPT-83, and KatG constructs)
  • 867 MPT83 Mycobacterium tuberculosis H37Rv VO_0012409 887155 15610010 Rv2873 AL123456 NP_217389 cell surface lipoprotein Protective antigen
  • M. tuberculosis DNA vaccine encoding Ag85B, MPT64 and MPT83
  • M. tuberculosis DNA vaccine (containing the ESAT-6, MPT-64, MPT-83, and KatG constructs)
  • 584 Mtb72F Mycobacterium tuberculosis VO_0011173 283801990 Protective antigen
  • M. tuberculosis Mtb72F Protein Subunit Vaccine
  • 910 panC Mycobacterium tuberculosis H37Rv 885459 15610738 Rv3602c BX842583 NP_218119 pantoate--beta-alanine ligase Virmugen
  • Mycobacterium tuberculosis panCD mutant vaccine
  • Mycobacterium tuberculosis RD1/panCD mutant vaccine
  • 911 panD Mycobacterium tuberculosis H37Rv 885596 15610737 Rv3601c BX842583 NP_218118 aspartate alpha-decarboxylase Virmugen
  • Mycobacterium tuberculosis panCD mutant vaccine
  • Mycobacterium tuberculosis RD1/panCD mutant vaccine
  • 819 PE20 Mycobacterium tuberculosis H37Rv VO_0012371 885537 57116919 Rv1806 JLDD01000021 YP_177843 PE family protein PE20 Protective antigen
  • DNA vaccine Rv1806-1807
  • 123 PepA Mycobacterium tuberculosis H37Rv VO_0010953 886924 15607267 Rv0125 CP003248 NP_214639 serine protease PepA Protective antigen
  • Mtb72f fusion protein
  • 249 PhoP Mycobacterium tuberculosis H37Rv 888772 15607897 Rv0757 BX842574 NP_215271 3R0J two component system response transcriptional positive regulator PHOP Virmugen
  • M. tuberculosis phoP mutant SO2
  • 822 PPE14 Mycobacterium tuberculosis H37Rv VO_0012374 885069 57116795 Rv0915c AL123456 YP_177765 PPE family protein PPE14 Protective antigen
    124 PPE18 Mycobacterium tuberculosis H37Rv VO_0010954 886073 57116841 Rv1196 AL123456 YP_177795 PPE family protein PPE18 Protective antigen
  • Mtb72f fusion protein
  • 820 PPE31 Mycobacterium tuberculosis H37Rv VO_0012372 885072 57116920 Rv1807 AL123456 YP_177653 PPE family protein PPE31 Protective antigen
  • DNA vaccine Rv1806-1807
  • 4398 PPE42 Mycobacterium tuberculosis H37Rv YP_177893 CDD:307116
    CDD:279771
    CDD:311933
    PPE family protein PPE42 Protective antigen
  • ID93/GLA-SE
  • 907 proC Mycobacterium tuberculosis H37Rv 887256 15607641 Rv0500 BX842573 NP_215014 pyrroline-5-carboxylate reductase Virmugen
  • Mycobacterium tuberculosis proC mutant vaccine
  • 865 PstS1 Mycobacterium tuberculosis H37Rv VO_0012407 885724 57116801 Rv0934 AL123456 YP_177770 1PC3 phosphate ABC transporter substrate-binding lipoprotein PstS Protective antigen
    818 PstS3 Mycobacterium tuberculosis H37Rv VO_0012370 885366 57116798 Rv0928 AL123456 YP_177768 phosphate ABC transporter substrate-binding lipoprotein PstS Protective antigen
    1015 RD1 Mycobacterium tuberculosis H37Rv 885777 15610750 Rv3614c BX842583 NP_218131 hypothetical protein Virmugen
  • Mycobacterium tuberculosis RD1/panCD mutant vaccine
  • 4395 Rv1813c Mycobacterium tuberculosis H37Rv NP_216329 CDD:316353 hypothetical protein Protective antigen
  • ID93/GLA-SE
  • 1064 Rv2660c Mycobacterium tuberculosis H37Rv 887222 15609797 Rv2660c CP009480 NP_217176 hypothetical protein Protective antigen
    117 SecA2 Mycobacterium tuberculosis H37Rv VO_0010950 885594 15608958 Rv1821 BX842577 NP_216337 1NL3 EMBL: AE000516
    EMBL: BX842577
    GenomeReviews: AE000516_GR
    GenomeReviews: AL123456_GR
    HSSP: O05885
    InterPro: IPR000185
    InterPro: IPR001650
    InterPro: IPR011115
    InterPro: IPR011116
    InterPro: IPR011130
    InterPro: IPR014018
    InterPro: IPR014021
    KEGG: mtc:MT1869
    KEGG: mtu:Rv1821
    Pfam: PF01043
    Pfam: PF07516
    Pfam: PF07517
    PIR: F70720
    PRINTS: PR00906
    PROSITE: PS01312
    PROSITE: PS51196
    TIGR: MT1869
    TubercuList: Rv1821
    UniProt: P66785
    preprotein translocase subunit SecA Virmugen
  • M. tuberculosis secA2 mutant
  • Mycobacterium tuberculosis lysA/secA2 mutant vaccine
  • 905 sigE Mycobacterium tuberculosis H37Rv 888751 15608361 Rv1221 BX842575 NP_215737 RNA polymerase sigma factor SigE Virmugen
  • Mycobacterium tuberculosis sigE mutant vaccine
  • 1196 sigF Mycobacterium tuberculosis CDC1551 922492 15842877 MT3385 AE000516 NP_337914 RNA polymerase sigma factor SigF Virmugen
  • Mycobacterium tuberculosis DeltasigF mutant vaccine
  • 120 SodA Mycobacterium tuberculosis H37Rv 886174 15610982 Rv3846 NC_000962.2 NC_000962.2 EMBL: AE000516
    EMBL: AF061030
    EMBL: BX842584
    EMBL: X52861
    Gene3D: G3DSA:3.90.149.10
    GenomeReviews: AE000516_GR
    GenomeReviews: AL123456_GR
    InterPro: IPR001189
    KEGG: mtc:MT3960
    KEGG: mtu:Rv3846
    LinkHub: P17670
    PANTHER: PTHR11404
    PDB: 1GN2
    PDB: 1GN3
    PDB: 1GN4
    PDB: 1GN6
    PDB: 1IDS
    Pfam: PF00081
    Pfam: PF02777
    PIR: S15205
    PRINTS: PR01703
    ProDom: PD000475
    PROSITE: PS00088
    TIGR: MT3960
    TubercuList: Rv3846
    UniProt: P17670
    SUPEROXIDE DISMUTASE [FE] SODA
  • M. tuberculosis DNA vaccine pAK4-sod
  • 908 trpD Mycobacterium tuberculosis H37Rv 887681 15609329 Rv2192c BX842579 NP_216708 2BPQ anthranilate phosphoribosyltransferase Virmugen
  • Mycobacterium tuberculosis trpD mutant vaccine