| Gene ID |
Gene Name |
Sequence Strain (Species/Organism) |
VO ID |
NCBI Gene ID |
NCBI Nucleotide GI |
NCBI Protein GI |
Locus Tag |
Genbank Accession |
Protein Accession |
3D structure: PDB ID |
Other Database IDs |
Protein Name |
Molecule Role |
Vaccines Involving this Gene |
|
137
|
ABRA |
Plasmodium falciparum Camp |
VO_0010926
|
811329
|
|
160047
|
|
|
|
|
swissprot:: P22620; GI:113005 |
p101/acidic basic repeat antigen |
Protective antigen |
Recombinant ABRA protein vaccine
|
|
640
|
AMA-1 from P. berghei |
Plasmodium berghei |
VO_0011224
|
55149604
|
|
1438889
|
|
|
|
|
CDD:280571 |
apical membrane antigen-1 |
Protective antigen |
|
|
653
|
AMA-1 from P. chabaudi |
Plasmodium chabaudi |
VO_0011237
|
3488885
|
|
1469500
|
|
|
|
|
CDD:302876 |
apical membrane antigen 1 |
Protective antigen |
P. chabaudi AMA1 Protein Vaccine
|
|
139
|
AMA1 from P. falciparum 3D7 |
Plasmodium falciparum 3D7 |
VO_0010923
|
810891
|
|
124804478
|
PF3D7_1133400 |
LN999945 |
XP_001348015 |
1Z40
|
UniProt: P22621 |
Apical membrane antigen 1 (AMA1); PF11_0344; AMA-1, Pf83, RMA1, RMA 1, rhoptry membrane antigen |
Protective antigen |
FMP1/AS02A
ChAd63-MVA AMA1
AMA1-C1Alhydrogel + CPG 7909
AMA1-C1Alhydrogel
NYVAC-Pf7
AMA 49-CPE
PfAMA1-FVO/ Alhydrogel
|
|
1745
|
AMA1 from P. knowlesi |
Plasmodium knowlesi strain H |
|
7320803
|
|
221056402
|
|
|
|
|
CDD:240241
EnsemblGenomes-Gn:PKH_093110
EnsemblGenomes-Tr:PKH_093110
GOA:B3L5E1
InterPro: IPR003298
InterPro: IPR024056
UniProtKB/TrEMBL: B3L5E1 |
apical merozoite antigen 1 |
Protective antigen |
P. knowlesi DNA vaccine encoding PkCSP, PkSSP2, PkAMA1, and PkMSP1p42
|
|
141
|
cjaA |
P. vivax SouthernMex-62 isolate |
VO_0010957
|
|
|
|
|
|
|
1Z27
|
CDD:270412
GOA:P94643
InterPro: IPR001638
UniProtKB/TrEMBL: P94643 |
|
Protective antigen |
|
|
633
|
CS from P. berghei str. ANKA |
Plasmodium berghei ANKA |
VO_0011217
|
3428738
|
|
AAA29577.1
|
PBANKA_040320 |
LK023119 |
XP_022712148 |
|
|
|
Protective antigen |
P. berghei CS Protein Subunit Vaccine
P. berghei DNA vaccine encoding PbCSP
P. berghei DNA vaccine CSP-3p28
|
|
634
|
CS from P. falciparum |
Plasmodium falciparum 3D7 |
VO_0011218
|
814364
|
|
552191
|
|
|
|
|
CDD:278517 |
circumsporozoite protein |
Protective antigen |
P. falciparum CS expressed in irradiated P. berghei as Vaccine
RTS,S/AS01
Pb(PfCS@UIS4)
NYVAC-Pf7
|
|
4825
|
CS from P. vivax |
|
|
|
|
AAA29526.1
|
|
|
|
|
CDD:237171
CDD:395043 |
circumsporozoite protein |
Protective antigen |
PvCS/Montanide ISA-51
|
|
635
|
CS from P. yoelii |
Plasmodium yoelii |
VO_0011219
|
3800426
|
|
1844509887
|
PY17X_0405400 |
LM993658 |
XP_728216 |
|
|
|
Protective antigen |
P. yoelii DNA vaccine pDIP/PyCSP. 1
|
|
4820
|
CSP from P. falciparum |
|
|
|
|
|
|
|
|
|
|
|
|
UK39
|
|
1743
|
CSP from P. knowlesi |
Plasmodium knowlesi strain H |
|
7322927
|
|
221060580
|
|
|
|
|
CDD:319368
EnsemblGenomes-Gn:PKH_134120
EnsemblGenomes-Tr:PKH_134120
GOA:B3LAV3
InterPro: IPR001841
InterPro: IPR013083
UniProtKB/TrEMBL: B3LAV3 |
circumsporozoite protein, putative |
Protective antigen |
P. knowlesi DNA vaccine encoding PkCSP, PkSSP2, PkAMA1, and PkMSP1p42
|
|
835
|
eba-175 |
Plasmodium falciparum 3D7 |
VO_0012382
|
2654998
|
|
296004911
|
PF3D7_0731500 |
AL844506 |
XP_001349207 |
|
|
|
Protective antigen |
P. falciparum DNA Vaccine encoding EBA-175
|
|
1307
|
Exported protein 1 from Plasmodium falciparum |
Plasmodium falciparum |
|
|
|
39843114
|
|
|
|
|
CDD:174853 |
exported protein 1 |
Protective antigen |
|
|
1081
|
FabB/FabF |
Plasmodium falciparum 3D7 |
|
3885996
|
|
296004726
|
PFF1275c |
AL844505 |
XP_966246 |
1OB1
|
|
|
Virmugen |
Plasmodium FabB/FabF mutant vaccine
|
|
645
|
FCR3S1.2-var1 |
Plasmodium falciparum |
VO_0011229
|
810160
|
|
2961468
|
|
|
|
|
CDD:292087
CDD:283158
CDD:281064
CDD:114603
CDD:292085 |
erythrocyte membrane protein 1 |
Protective antigen |
|
|
812
|
GLURP |
Plasmodium falciparum 3D7 |
VO_0011343
|
810501
|
|
124802897
|
PF3D7_1035300 |
LN999944 |
XP_001347628 |
|
|
glutamate-rich protein |
Protective antigen |
|
|
644
|
HEP17 |
Plasmodium yoelii |
VO_0011228
|
3790041
|
|
1399353
|
|
|
|
|
CDD:284100 |
hepatocyte erythrocyte protein 17 kDa |
Protective antigen |
P. yoelii DNA vaccine encoding PyHEP17 Protein
|
|
1742
|
HSP60 from P. yoelii |
Plasmodium yoelii strain 17X(NL) |
|
3790277
|
|
3885993
|
|
|
|
|
CDD:185455
CDD:239460 |
heat shock protein 60 |
Protective antigen |
P. yoelii DNA vaccine pPyHsp60-VR1012
|
|
657
|
Hsp90 |
Plasmodium falciparum |
VO_0011241
|
2655065
|
|
1093612
|
|
|
|
|
CDD:240341
CDD:214643
CDD:238030
CDD:278607 |
|
Protective antigen |
P. falciparum Hsp90 Protein Subunit Vaccine
|
|
649
|
Kbeta |
Plasmodium falciparum 3D7 |
VO_0011233
|
813054
|
|
124506397
|
PF3D7_0524000 |
AL844504 |
XP_001351796 |
|
|
|
Protective antigen |
|
|
142
|
LSA-1 from Plasmodium falciparum |
Plasmodium falciparum |
|
|
|
510186
|
|
|
|
|
CDD:183692
HSSP: 1D7M
UniProtKB/TrEMBL: Q25887 |
liver stage antigen-1 |
Other |
P. falciparam liver-stage peptides and lipopeptides
Chimeras of P. falciparum LSA-1 epitope T1 with MS2 bacteriophage capsids
NYVAC-Pf7
|
|
834
|
LSA-3 |
Plasmodium falciparum 3D7 |
VO_0012381
|
812783
|
|
124801463
|
PF3D7_0220000 |
LN999943 |
XP_001349701 |
|
|
Liver stage antigen 3 |
Protective antigen |
P. falciparum LSA-3 Protein Vaccine
|
|
143
|
MSP-1 from P. falciparum |
Plasmodium falciparum 3D7 |
VO_0010958
|
813575
|
|
124507147
|
PF3D7_0930300 |
AL844508 |
XP_001352170 |
|
CDD:289698
CDD:304395 |
merozoite surface protein 1 |
Protective antigen |
P. falciparum vaccine Combination B
P. vivax MSP1-19-PADRE
P. falciparum MSP1 from transgenic mice with Freund's adjuvant
ChAd63-MVA MSP1
NYVAC-Pf7
|
|
637
|
msp-8 |
Plasmodium yoelii |
VO_0011221
|
3792405
|
|
58197887
|
|
|
|
|
CDD:315598 |
merozoite surface protein 8 |
Protective antigen |
|
|
641
|
MSP1 from P. berghei |
Plasmodium berghei |
VO_0011225
|
|
|
1762646
|
|
|
|
|
|
merozoite surface protein 1 |
Protective antigen |
P. berghei MSP1 Protein Vaccine
|
|
1746
|
MSP1 from P. knowlesi |
Plasmodium knowlesi strain H |
|
7320035
|
|
XP_002258582.2
|
|
|
|
|
CDD:284802
CDD:289698
CDD:289699
EnsemblGenomes-Gn:PKH_072850
EnsemblGenomes-Tr:PKH_072850
GOA:B3L2X8
InterPro: IPR010901
InterPro: IPR024730
InterPro: IPR024731
UniProtKB/TrEMBL: B3L2X8 |
merozoite surface protein 1, MSP-1 |
Protective antigen |
P. knowlesi DNA vaccine encoding PkCSP, PkSSP2, PkAMA1, and PkMSP1p42
|
|
628
|
MSP1 from P. yoelii str. 17XNL |
Plasmodium yoelii |
VO_0011212
|
3791597
|
|
82596427
|
PY17X_0834400 |
LK934636 |
XP_726257 |
|
|
|
Protective antigen |
P. yoelii DNA vaccine encoding MSP1
rBCGMSP1-15
|
|
646
|
MSP1 from P.vivax |
Plasmodium vivax |
VO_0011230
|
|
AF435639.1
|
26985160
|
|
|
|
2NPR
|
CDD:299863
CDD:284802
CDD:289698
CDD:289699 |
merozoite surface protein 1 |
Protective antigen |
|
|
4924
|
MSP2 |
|
|
812660
|
|
CAA70446.1
|
|
|
|
|
CDD:144541
GOA:O00790
InterPro: IPR001136
UniProtKB/TrEMBL: O00790 |
merozoite surface antigen 2 |
Protective antigen |
P. falciparum MSA-2 subunit vaccine
|
|
636
|
msp3 |
Plasmodium falciparum |
VO_0011220
|
810502
|
|
113207288
|
|
|
|
|
CDD:284533
InterPro: IPR010784
UniProtKB/TrEMBL: Q0KGB6 |
merozoite surface protein 3 |
Protective antigen |
P. falciparum MSP3 Protein Subunit Vaccine
MSP3-CRM-Vac4All/ Alhydrogel®
|
|
4925
|
MSP4 |
Plasmodium falciparum 3D7 |
|
812662
|
|
124801002
|
PF3D7_0207000 |
AF295306 |
XP_001349580 |
|
|
|
Protective antigen |
P. falciparum MSP4 with AFCo1 Adjuvant
|
|
652
|
MSP4/5 |
Plasmodium yoelii |
VO_0011236
|
3800676
|
AY563017.1
|
49798469
|
|
|
|
|
CDD:289699 |
merozoite surface protein 4/5 |
Protective antigen |
P. yoelii MSP1 and MSP4/5 Proteins Subunit Vaccine
|
|
1027
|
P36p |
Plasmodium berghei str. ANKA |
|
3424772
|
|
68068733
|
PB000799.01.0 |
CAAI01001447 |
XP_676277 |
|
|
|
Virmugen |
P. berghei p36p mutant vaccine
|
|
4941
|
p52 |
Plasmodium falciparum 3D7 |
|
9221796
|
|
124505231
|
PF3D7_0404500 |
AL844503 |
XP_001351357 |
|
CDD:429455 |
Sporozoite surface protein P36p |
Virmugen |
|
|
874
|
pfCelTOS |
|
|
811213
|
AB194052.1
|
62954730
|
|
|
|
|
CDD:163532 |
PF cell-traversal protein |
Protective antigen |
P. falciparum pfCelTos protein vaccine
FMP012 with AS01B adjuvant system
|
|
639
|
Pfen |
Plasmodium falciparum 3D7 |
VO_0011223
|
810313
|
|
124802328
|
PF3D7_1015900 |
LN999944 |
XP_001347440 |
|
|
|
Protective antigen |
P. falciparum Pfen Protein Subunit Vaccine
|
|
4838
|
PfP0 |
|
|
810860
|
|
EWC88043.1
|
|
|
|
|
CDD:240285
CDD:240221 |
60S acidic ribosomal protein P0 |
Protective antigen |
PfP0 P-BSA
|
|
140
|
Pfs230 |
|
|
812682
|
|
|
|
|
|
|
|
PFB0405w, transmission-blocking target antigen s230 precursor |
Protective antigen |
Plasmodium DNA vaccine encoding Pfs230 using GPI anchor signal sequence
Pfs230D1-EPA/Matrix-M
|
|
4822
|
Pfs25 from P. falciparum 3D7 |
Plasmodium falciparum 3D7 |
|
810460
|
|
124802764
|
PF3D7_1031000 |
LN999944 |
XP_001347587 |
|
|
|
Protective antigen |
Pfs25-IMX313/Matrix-M
NYVAC-Pf7
Pfs25-EPA / AS01
Pfs25-EPA/Alhydrogel
Pfs25 VLP-FhCMB
Pfs25/ Montanide ISA 51
ChAd63/MVA Pfs25-IMX313
|
|
4833
|
Pfs48/45 |
|
|
814212
|
|
AHA91190.1
|
|
|
|
|
CDD:173430 |
Pfs48/45 |
Protective antigen |
Pfs48/45 in Matrix-M
|
|
4823
|
PvCelTOS |
|
|
5476572
|
|
VUZ98878.1
|
|
|
|
|
CDD:408441 |
cell traversal protein for ookinetes and sporozoites |
Protective antigen |
Ad-protein PvCelTOS
Ad-MVA PvCelTOS
Ad-VLPs PvCelTOS
|
|
4831
|
PvDBPII |
|
|
5471431
|
|
ACJ54188.1
|
|
|
|
|
CDD:432515
CDD:140204 |
duffy binding surface protein region II |
Protective antigen |
PvDBPII/Matrix-M1
ChAd63 MVA PvDBP
PvRII/ AS02A
PvRII/ Montanide ISA 720
PvRII/ Alhydrogel
|
|
4836
|
Pvs25 |
Plasmodium vivax |
|
5471385
|
|
156081935
|
PVX_111175 |
AAKM01002769 |
XP_001608460 |
|
|
|
Protective antigen |
P. vivax PVS25 with Montanide ISA-720
Pvs25-IMX313/Matrix-M1
Pvs25 mRNA–LNP
|
|
1028
|
PY01338 |
|
|
|
23485916
|
23485917
|
|
|
EAA20641.1 |
|
|
hypothetical protein |
Virmugen |
|
|
1083
|
Py36 |
Plasmodium yoelii 17XNL |
|
|
|
23479924
|
|
|
|
|
CDD:185624 |
p36 protein |
Virmugen |
P. yoelii p36/p52 mutant vaccine
|
|
1082
|
Py52 |
|
|
|
15193061
|
15193062
|
|
|
AAK91678.1 |
|
|
Py52 |
Virmugen |
P. yoelii p36/p52 mutant vaccine
|
|
144
|
RESA |
Plasmodium falciparum 3D7 |
VO_0010959
|
813159
|
|
124505681
|
PF3D7_0102200 |
AL844501 |
XP_001350954 |
|
|
RESA, ring-infected erythrocyte surface antigen, Pf155, MAL1P1.13 |
Protective antigen |
P. falciparum vaccine Combination B
|
|
4834
|
RH5 |
Plasmodium falciparum 3D7 |
|
814549
|
|
124505127
|
PF3D7_0323400 |
AL844502 |
XP_001351305 |
|
CDD:240419 |
Reticulocyte-binding protein homolog 5 |
Protective antigen |
ChAd63-MVA RH5
PfRH5 DNA Vaccine
|
|
4938
|
SERA |
|
|
|
|
AAF37557.1
|
|
|
|
|
CDD:185641 |
serine-repeat antigen protein |
Protective antigen |
NYVAC-Pf7
|
|
626
|
SERA-5 |
Plasmodium falciparum |
VO_0011210
|
812668
|
|
238629807
|
|
|
|
3CH2
|
CDD:185641 |
serine repeat antigen 5 |
Protective antigen |
P. falciparum Subunit SE36 Protein Vaccine
|
|
1741
|
SSP2 |
Plasmodium yoelii |
|
3830241
|
|
45645179
|
|
|
|
|
CDD:240420
CDD:238748
CDD:214559 |
Sporozoite surface protein 2 |
Protective antigen |
P. yoelii DNA vaccine encoding PySSP2
|
|
1744
|
SSP2 from P. knowlesi |
Plasmodium knowlesi strain H |
|
7322479
|
|
221058683
|
|
|
|
|
CDD:240420
EnsemblGenomes-Gn:PKH_121770
EnsemblGenomes-Tr:PKH_121770
InterPro: IPR000884
InterPro: IPR002035
UniProtKB/TrEMBL: B3L8N1 |
sporozoite surface protein 2, putative |
Protective antigen |
P. knowlesi DNA vaccine encoding PkCSP, PkSSP2, PkAMA1, and PkMSP1p42
|
|
1306
|
SSP2 from Plasmodium falciparum |
Plasmodium falciparum |
|
|
|
160691
|
|
|
|
|
CDD:185620
CDD:29244
CDD:199489 |
sporozoite surface protein 2 |
Protective antigen |
NYVAC-Pf7
|
|
145
|
STARP |
Plasmodium falciparum |
|
|
|
|
|
|
|
|
PlasmoDB:PF07_0006 |
starp antigen |
|
P. falciparam liver-stage peptides and lipopeptides
|
|
138
|
TRAP from P. falciparum |
Plasmodium falciparum 3D7 |
VO_0010920
|
814170
|
|
124513464
|
PF3D7_1335900 |
AL844509 |
XP_001350088 |
|
|
Thrombospondin-related anonymous protein (TRAP), SSP-2, SSP2, Sporozoite specific protein 2, Sporozoite surface protein 2 |
Protective antigen |
P. falciparum DNA and MVA encoding ME-TRAP
ChAd63-MVA ME-TRAP
|
|
1029
|
UIS3 |
Plasmodium yoelii yoelii str. 17XNL |
|
3830198
|
|
83315853
|
PY03011 |
AABL01000850 |
XP_730972 |
2VWA
|
|
|
Virmugen |
P. yoelii UIS3 mutant vaccine
|
|
894
|
UIS4 |
Plasmodium yoelii yoelii str. 17XNL |
|
3853948
|
|
82753006
|
PY00876 |
AABL01000235 |
XP_727503 |
|
CDD:158776
CDD:152003 |
upregulated in infective sporozoites 3 |
Virmugen |
|
