VO Banner
Search: for Help
Vaxjo Home
News and Updates
Vaxjo Query
Selected Adjuvants
adamantylamide dipeptide vaccine adjuvant
aluminum hydroxide vaccine adjuvant
alhydrogel vaccine adjuvant
Data Submission
Data Exchange
Data Download
Contact Us

Vaxjo: Frequently Asked Questions

1. What is Vaxjo?

Answer: Vaxjo is a vaccine adjuvant database and analysis resource. Vaxjo is a independent program as part of VIOLIN.

2. What are the targeted users of Vaxjo?

Answer: The targeted users of Vaxjo include vaccine adjuvant users and researchers, and bioinformaticians interested in vaccine research.

3. What are vaccine adjuvants?

Answer: Vaccine adjuvants are compounds that enhance the specific immune responses against co-inoculated antigens in vaccines.

4. How are adjuvants classified?

Answer: Adjuvants can be classified based on their source, mechanism of action or physicochemical properties (reference: PMID:15479434):

  1. Based on the mechanism, adjuvants are classified by Edelman into three groups: (i) active immunostimulants: substances that increase the immune response to the co-administered antigen; (ii) carriers: immunogenic proteins providing T-cell help; and (iii) vehicle adjuvants: oil emulsions or liposomes serving as a matrix for antigens and stimulating the immune response.
  2. According to the administrative route, adjuvants can be classified into mucosal and parenteral adjuvants.
  3. Adjuvants can be classified into: alum salts and other mineral adjuvants; tensoactive agents; bacterial derivatives; vehicles and slow release materials or cytokines.
  4. Adjuvants can be classified into the groups: gel-based adjuvants, tensoactive agents, bacterial products, oil emulsions, particulated adjuvants, fusion proteins or lipopeptides.

5. to be continued ...