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Vaccine Detail

IPNV DNA vaccine pEGFP-N1-SegA and pEGFP-N1-VP2
Vaccine Information
  • Vaccine Ontology ID: VO_0004493
  • Type: DNA vaccine
  • Status: Research
  • Host Species as Laboratory Animal Model: Salmon
  • ORF gene engineering:
    • Type: DNA vaccine construction
    • Description: Vector pEGFP-N1 expressed the polyprotein gene (Bases131-3046) and the VP2 gene from strain Rauma (Mikalsen et al., 2004).
    • Detailed Gene Information: Click Here.
  • VP2 gene engineering:
    • Type: DNA vaccine construction
    • Detailed Gene Information: Click Here.
  • Vector: pEGFP-N1 (Mikalsen et al., 2004)
  • Immunization Route: Microinjection
Host Response

Fish Response

  • Vaccine Immune Response Type: VO_0000286
  • Efficacy: A high level of protection was induced (Mikalsen et al., 2004).
References
Mikalsen et al., 2004: Mikalsen AB, Torgersen J, Aleström P, Hellemann AL, Koppang EO, Rimstad E. Protection of atlantic salmon Salmo salar against infectious pancreatic necrosis after DNA vaccination. Diseases of aquatic organisms. 2004; 60(1); 11-20. [PubMed: 15352520].