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Vaccine Detail
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IPNV DNA vaccine pEGFP-N1-SegA and pEGFP-N1-VP2 |
| Vaccine Information |
- Vaccine Ontology ID: VO_0004493
- Type: DNA vaccine
- Status: Research
- Host Species as Laboratory Animal Model: Salmon
- ORF
gene engineering:
- Type: DNA vaccine construction
- Description: Vector pEGFP-N1 expressed the polyprotein gene (Bases131-3046) and the VP2 gene from strain Rauma (Mikalsen et al., 2004).
- Detailed Gene Information: Click Here.
- VP2
gene engineering:
- Type: DNA vaccine construction
- Detailed Gene Information: Click Here.
- Vector: pEGFP-N1 (Mikalsen et al., 2004)
- Immunization Route: Microinjection
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| Host Response |
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Fish Response
- Vaccine Immune Response Type: VO_0000286
- Efficacy: A high level of protection was induced (Mikalsen et al., 2004).
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| References |
Mikalsen et al., 2004: Mikalsen AB, Torgersen J, Aleström P, Hellemann AL, Koppang EO, Rimstad E. Protection of atlantic salmon Salmo salar against infectious pancreatic necrosis after DNA vaccination. Diseases of aquatic organisms. 2004; 60(1); 11-20. [PubMed: 15352520].
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