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Vaccine Detail

Duck hepatitis virus 1 DNA vaccine pSCA/VP1
Vaccine Information
  • Vaccine Ontology ID: VO_0004575
  • Type: DNA vaccine
  • Status: Research
  • Host Species as Laboratory Animal Model: Ducklings
  • VP1 gene engineering:
    • Type: DNA vaccine construction
    • Detailed Gene Information: Click Here.
  • Vector: pSCA1 (Fu et al., 2012)
  • Immunization Route: Intramuscular injection (i.m.)
Host Response

Ducks Response

  • Vaccine Immune Response Type: VO_0003057
  • Immune Response: DHV-1-specific antibodies, neutralizing antibodies and lymphocyte proliferation were well induced in ducklings (Fu et al., 2012).
  • Efficacy: Vaccination with pSCA/VP1 could significantly reduce the onset and duration of viremia and decrease virus replication in ducklings (Fu et al., 2012).
References
Fu et al., 2012: Fu Y, Chen Z, Li C, Liu G. Protective immune responses in ducklings induced by a suicidal DNA vaccine of the VP1 gene of duck hepatitis virus type 1. Veterinary microbiology. 2012; 160(3-4); 314-318. [PubMed: 22819169].