• Vaccine Name: T. annulata Tams1 Protein Vaccine
• Target Pathogen: Theileria annulata
• Target Disease: Theileriosis
• Vaccine Ontology ID: VO_0004181
• Type: Subunit vaccine
• Status: Research
• TA17050 merozoite-piroplasm surface antigen Tams1 gene engineering:
  • Type: Recombinant protein preparation
  • Description:
  • Detailed Gene Information: Click Here.
• Adjuvant:
  • Adjuvant name:
  • VO adjuvant ID: VO_0000757
  • Description: Immunostimulating complexes (ISCOMs) (d'Oliveira et al., 1997).
• Immunization Route: Intramuscular injection (i.m.)

Cattle Response

• Vaccination Protocol: Calves were immunized via intramuscular injection with 1 ml ISCOM vaccine given intramuscularly, containing 20 μg re-(Tamsl-l or Tams1 -2) (d'Oliveira et al., 1997).
• Challenge Protocol: Calves were challenged with T. annulata Ankara strain (d'Oliveira et al., 1997).
• Efficacy: All calves vaccinated with ISCOMs proved to be protected from T. annulata infection and had generated antibodies against both re-(Tams1-1 and Tams1-2) at the time of challenge (d'Oliveira et al., 1997).