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Vaccine Detail

Chimaeric HBV core particles carrying Puumala virus nucleocapsid protein fragments
Vaccine Information
  • Vaccine Name: Chimaeric HBV core particles carrying Puumala virus nucleocapsid protein fragments
  • Target Pathogen: Hantavirus
  • Target Disease: Hantavirus Pulmonary Syndrome
  • Vaccine Ontology ID: VO_0004120
  • Type: Recombinant vector vaccine
  • Antigen: The Puumala virus nucleocapsid protein (Ulrich et al., 1998).
  • Preparation: Chimaeric hepatitis B virus (HBV) core particles were constructed to carry defined fragments of the Puumala virus nucleocapsid protein. Puumala is a European hantavirus (Ulrich et al., 1998).
Host Response
References
Ulrich et al., 1998: Ulrich R, Lundkvist A, Meisel H, Koletzki D, Sjolander KB, Gelderblom HR, Borisova G, Schnitzler P, Darai G, Kruger DH. Chimaeric HBV core particles carrying a defined segment of Puumala hantavirus nucleocapsid protein evoke protective immunity in an animal model. Vaccine. 1998 Jan-Feb; 16(2-3); 272-80. [PubMed: 9607042 ].