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Vaccine Detail

Tetanus Toxoid with Calcium Phosphate
Vaccine Information
  • Vaccine Name: Tetanus Toxoid with Calcium Phosphate
  • Target Pathogen: Clostridium tetani
  • Target Disease: Tetanus
  • Vaccine Ontology ID: VO_0004230
  • Type: Toxoid vaccine
  • Status: Research
  • Adjuvant: calcium phosphate vaccine adjuvant
  • Preservative: Thimerosal (Gupta and Siber, 1994).
  • Immunization Route: subcutaneous injection
Host Response

Mouse Response

  • Host Strain: BALB/c
  • Vaccination Protocol: MIce were injected with TT preparation subcutaneously and boosted 30 days later (Gupta and Siber, 1994)
  • Immune Response: Mice immunized with CP-TT had IgG levels than mice immunized with TT adsorbed to aluminum phosphate (Gupta and Siber, 1994).
References
Gupta and Siber, 1994: Gupta RK, Siber GR. Comparison of adjuvant activities of aluminium phosphate, calcium phosphate and stearyl tyrosine for tetanus toxoid. Biologicals : journal of the International Association of Biological Standardization. 1994; 22(1); 53-63. [PubMed: 8068314].