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Vaccine Detail
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Recombinant Tir Protein Vaccine |
| Vaccine Information |
- Vaccine Name: Recombinant Tir Protein Vaccine
- Target Pathogen: Escherichia coli
- Target Disease: Hemorrhagic colitis
- Vaccine Ontology ID: VO_0004256
- Type: Subunit vaccine
- Status: Research
- Host Species as Laboratory Animal Model: Mice
- Antigen: Recombinant Tir protein (Fan et al., 2011).
- Tir
gene engineering:
- Type: Recombinant protein preparation
- Description:
- Detailed Gene Information: Click Here.
- Immunization Route: intranasal immunization
- Description: Purified Tir protects mice against EHEC challenge after intranasal immunization and is worth further clinical development as a vaccine candidate (Fan et al., 2011).
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| Host Response |
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| References |
Fan et al., 2011: Fan HY, Wang L, Luo J, Long BG. Protection against Escherichia coli O157:H7 challenge by immunization of mice with purified Tir proteins. Molecular biology reports. 2011; ; . [PubMed: 21567195].
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