• Vaccine Name: HIV recombinant gp160 Protein Vaccine
• Target Pathogen: Human Immunodeficiency Virus
• Target Disease: Acquired Immunodeficiency Syndrome (AIDS)
• Vaccine Ontology ID: VO_0004274
• Type: Subunit vaccine
• Status: Research
• Antigen: Recombinant gp160 (Barrett et al., 1989).
• Adjuvant:
  • Adjuvant name:
  • VO adjuvant ID: VO_0001291
  • Description: 0.2% Al(OH)3 and 0.25% deoxycholate (Barrett et al., 1989).
• Immunization Route: subcutaneous injection

Mouse Response

• Vaccination Protocol: The potency of the vaccine was determined by injecting mice with serial dilutions of gp160 alone or adjuvanted with different formulations. Groups of 10 mice were injected subcutaneously with 1 ml of fourfold dilutions of the test substance. A total of 50 mice were injected in each test (Barrett et al., 1989).
• Immune Response: The highest potency in mice was obtained using a preparation with 0.2% Al(OH)3 and 0.25% deoxycholate (Barrett et al., 1989).