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Vaccine Detail

SARS-CoV E gene mutant vaccine
Vaccine Information
  • Vaccine Name: SARS-CoV E gene mutant vaccine
  • Target Pathogen: SARS-CoV
  • Target Disease: Severe Acute Respiratory Syndrome (SARS)
  • Vaccine Ontology ID: VO_0002993
  • Type: Live, attenuated vaccine
  • Status: Research
  • Host Species as Laboratory Animal Model: Hamster
  • envelope protein (E) gene of SARS-CoV gene engineering:
    • Type: Gene mutation
    • Description: This E gene is from SARS coronavirus (Lamirande et al., 2008).
    • Detailed Gene Information: Click Here.
  • Immunization Route: intranasal immunization
Host Response

Hamster Response

References
Lamirande et al., 2008: Lamirande EW, DeDiego ML, Roberts A, Jackson JP, Alvarez E, Sheahan T, Shieh WJ, Zaki SR, Baric R, Enjuanes L, Subbarao K. A live attenuated severe acute respiratory syndrome coronavirus is immunogenic and efficacious in golden Syrian hamsters. Journal of virology. 2008; 82(15); 7721-7724. [PubMed: 18463152].