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Vaccine Detail

Salmonella Gallinarum crp mutant vaccine
Vaccine Information
  • Vaccine Name: Salmonella Gallinarum crp mutant vaccine
  • Target Pathogen: Salmonella spp.
  • Target Disease: Salmonellosis
  • Vaccine Ontology ID: VO_0002879
  • Type: Live, attenuated vaccine
  • Status: Research
  • Host Species as Laboratory Animal Model: Mouse
  • crp gene engineering:
    • Type: Gene mutation
    • Description: This crp mutant is from Salmonella Gallinarum (Rosu et al., 2007).
    • Detailed Gene Information: Click Here.
  • Immunization Route: Intramuscular injection (i.m.)
Host Response

Mouse Response

  • Persistence: A crp mutant is attenuated in mice (Rosu et al., 2007).
  • Efficacy: A crp mutant induces significant protection in mice from challenge with wild type S. Gallinarum (Rosu et al., 2007).
References
Rosu et al., 2007: Rosu V, Chadfield MS, Santona A, Christensen JP, Thomsen LE, Rubino S, Olsen JE. Effects of crp deletion in Salmonella enterica serotype Gallinarum. Acta veterinaria Scandinavica. 2007; 49; 14. [PubMed: 17488512].