VIOLIN Logo
VO Banner
Search: for Help
About
Introduction
Statistics
VIOLIN News
Your VIOLIN
Register or Login
Submission
Tutorial
Vaccine & Components
Vaxquery
Vaxgen
VBLAST
Protegen
VirmugenDB
DNAVaxDB
CanVaxKB
Vaxjo
Vaxvec
Vevax
Huvax
Vaccine Mechanisms
Vaximmutordb
Vaxism
Vaxar
Vaccine Literature
VO-SciMiner
Litesearch
Vaxmesh
Vaxlert
Vaccine Design
Vaxign
Community Efforts
Vaccine Ontology
ICoVax 2012
ICoVax 2013
Advisory Committee
Vaccine Society
Vaxperts
VaxPub
VaxCom
VaxLaw
VaxMedia
VaxMeet
VaxFund
VaxCareer
Data Exchange
V-Utilities
VIOLINML
Help & Documents
Publications
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

Vaccine Detail

Psuedorabies virus glycoprotein M mutant vaccine
Vaccine Information
  • Vaccine Name: Psuedorabies virus glycoprotein M mutant vaccine
  • Target Pathogen: Pseudorabies virus
  • Target Disease: Aujeszky's disease
  • Vaccine Ontology ID: VO_0002985
  • Type: Live, attenuated vaccine
  • Status: Research
  • Host Species as Laboratory Animal Model: Pig
  • glycoprotein M gene engineering:
    • Type: Gene mutation
    • Description: This glycoprotein M mutant is from Pseudorabies virus (Dijkstra et al., 1997).
    • Detailed Gene Information: Click Here.
  • Immunization Route: intranasal immunization
Host Response

Pig Response

  • Persistence: A glycoprotein M mutant is attenuated in piglets (Dijkstra et al., 1997).
  • Efficacy: A glycoprotein M mutant induces protection in piglets from challenge with wild type Pseudorabies virus (Dijkstra et al., 1997).
References
Dijkstra et al., 1997: Dijkstra JM, Gerdts V, Klupp BG, Mettenleiter TC. Deletion of glycoprotein gM of pseudorabies virus results in attenuation for the natural host. The Journal of general virology. 1997; 78 ( Pt 9); 2147-2151. [PubMed: 9292000].