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Vaccine Detail
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Pseudorabies virus gp50/gp63 mutant vaccine |
| Vaccine Information |
- Vaccine Name: Pseudorabies virus gp50/gp63 mutant vaccine
- Target Pathogen: Pseudorabies virus
- Target Disease: Aujeszky's disease
- Type: Live, attenuated vaccine
- Status: Research
- Host Species as Laboratory Animal Model: Pig
- gp50
gene engineering:
- Type: Gene mutation
- Description: This gp50/gp63 mutant is from Suid herpesvirus 1 (Peeters et al., 1994).
- Detailed Gene Information: Click Here.
- gp63
gene engineering:
- Type: Gene mutation
- Description: This gp50/gp63 mutant is from Suid herpesvirus 1 (Peeters et al., 1994).
- Detailed Gene Information: Click Here.
- Immunization Route: Intramuscular injection (i.m.)
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| Host Response |
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Pig Response
- Persistence: A gp50/gp63 mutant is attenuated in pigs (Peeters et al., 1994).
- Efficacy: A gp50/gp63 mutant vaccine induces protection in pigs from challenge with wild type Pseudorabies virus (Peeters et al., 1994).
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| References |
Peeters et al., 1994: Peeters B, Bouma A, de Bruin T, Moormann R, Gielkens A, Kimman T. Non-transmissible pseudorabies virus gp50 mutants: a new generation of safe live vaccines. Vaccine. 1994; 12(4); 375-380. [PubMed: 8178562].
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