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Vaccine Detail

Porcine respiratory and reproductive syndrome virus GP5 protein mutant vaccine
Vaccine Information
  • Vaccine Name: Porcine respiratory and reproductive syndrome virus GP5 protein mutant vaccine
  • Target Pathogen: Porcine respiratory and reproductive syndrome virus
  • Target Disease: Porcine Reproductive and Respiratory Syndrome (PRRS), Blue-Ear Pig Disease
  • Product Name: HuN4-F112
  • Vaccine Ontology ID: VO_0002982
  • Type: Live, attenuated vaccine
  • Status: Research
  • Host Species as Laboratory Animal Model: Pig
  • GP5 protein gene engineering:
    • Type: Gene mutation
    • Description: This GP5 protein mutant is from Porcine reproductive and respiratory syndrome virus (Tian et al., 2009).
    • Detailed Gene Information: Click Here.
  • Immunization Route: Intramuscular injection (i.m.)
Host Response

Pig Response

  • Persistence: A GP5 protein mutant is attenuated in piglets (Tian et al., 2009).
  • Efficacy: A GP5 protein mutant induces protection in piglets from challenge with wild type HP-PRRSV (Tian et al., 2009).
References
Tian et al., 2009: Tian ZJ, An TQ, Zhou YJ, Peng JM, Hu SP, Wei TC, Jiang YF, Xiao Y, Tong GZ. An attenuated live vaccine based on highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) protects piglets against HP-PRRS. Veterinary microbiology. 2009; 138(1-2); 34-40. [PubMed: 19339125].