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Vaccine Detail

Mycobacterium tuberculosis leuD mutant vaccine
Vaccine Information
  • Vaccine Name: Mycobacterium tuberculosis leuD mutant vaccine
  • Target Pathogen: Mycobacterium tuberculosis
  • Target Disease: Tuberculosis
  • Vaccine Ontology ID: VO_0002782
  • Type: Live, attenuated vaccine
  • Status: Research
  • Host Species as Laboratory Animal Model: Mouse
  • leuD gene engineering:
    • Type: Gene mutation
    • Description: This leuD mutant is from Mycobacterium tuberculosis (Hondalus et al., 2000).
    • Detailed Gene Information: Click Here.
  • Immunization Route: Intravenous injection (i.v.)
Host Response

Mouse Response

References
Hondalus et al., 2000: Hondalus MK, Bardarov S, Russell R, Chan J, Jacobs WR Jr, Bloom BR. Attenuation of and protection induced by a leucine auxotroph of Mycobacterium tuberculosis. Infection and immunity. 2000; 68(5); 2888-2898. [PubMed: 10768986].