• Vaccine Name: Herpes simplex virus 1 gH mutant vaccine
• Target Pathogen: Herpes simplex virus type 1 and 2
• Target Disease: Herpes
• Vaccine Ontology ID: VO_0002971
• Type: Live, attenuated vaccine
• Status: Research
• Host Species as Laboratory Animal Model: Mouse
• gH gene engineering:
  • Type: Gene mutation
  • Description: This gH mutant is from Herpes simplex virus type 1 (Farrell et al., 1994).
  • Detailed Gene Information: Click Here.
• Immunization Route: Ear pinna

Mouse Response

• Persistence: A gH mutant is attenuated in mice (Farrell et al., 1994).
• Efficacy: A gH mutant induces significant protection in mice from challenge with wild type HSV-1 (Farrell et al., 1994).