|
|
Vaccine Detail
|
Gallid herpesvirus 1 UL23 mutant vaccine |
| Vaccine Information |
- Vaccine Name: Gallid herpesvirus 1 UL23 mutant vaccine
- Target Pathogen: Gallid herpesvirus 1
- Target Disease: Avian infectious laryngotracheitis, Fowl Laryngotracheitis
- Vaccine Ontology ID: VO_0002967
- Type: Live, attenuated vaccine
- Status: Research
- Host Species as Laboratory Animal Model: Chicken
- UL23
gene engineering:
- Type: Gene mutation
- Description: This UL23 mutant is from Gallid herpesvirus 1 (Han et al., 2002).
- Detailed Gene Information: Click Here.
- Immunization Route: Intraocular immunization
|
| Host Response |
|
Chicken Response
- Persistence: A UL23 mutant is attenuated in chickens (Han et al., 2002).
- Efficacy: A UL23 mutant induces significant protection in chickens from challenge with wild type GHV-1 (Han et al., 2002).
|
| References |
Han et al., 2002: Han MG, Kweon CH, Mo IP, Kim SJ. Pathogenicity and vaccine efficacy of a thymidine kinase gene deleted infectious laryngotracheitis virus expressing the green fluorescent protein gene. Archives of virology. 2002; 147(5); 1017-1031. [PubMed: 12021870].
|
|
