• Vaccine Name: Equid herpesvirus TK mutant vaccine
• Target Pathogen: Equid herpesvirus
• Target Disease: Equine Rhinopneumonitis
• Product Name: PR1
• Vaccine Ontology ID: VO_0002957
• Type: Live, attenuated vaccine
• Status: Research
• Host Species as Laboratory Animal Model: Mouse, horse
• TK gene engineering:
  • Type: Gene mutation
  • Description: This TK mutant is from Equid herpesvirus 1 (Slater et al., 1993).
  • Detailed Gene Information: Click Here.
• Immunization Route: intranasal immunization

Mouse Response

• Persistence: A TK mutant is attenuated in mice (Slater et al., 1993).
• Efficacy: A TK mutant induces significant protection from challenge with wild type EHV (Slater et al., 1993).

Horse Response

• Persistence: A TK mutant is attenuated in foals (Slater et al., 1993).
• Efficacy: A TK mutant provides partial protection in foals from challenge with wild type EHV (Slater et al., 1993).