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Vaccine Detail

Edwardsiella tarda esrB mutant vaccine
Vaccine Information
  • Vaccine Name: Edwardsiella tarda esrB mutant vaccine
  • Target Pathogen: Edwardsiella tarda
  • Vaccine Ontology ID: VO_0002833
  • Type: Live, attenuated vaccine
  • Status: Research
  • Host Species as Laboratory Animal Model: Fish
  • esrB gene engineering:
    • Type: Gene mutation
    • Description: This esrB mutant is from Edwardsiella tarda (Lan et al., 2007).
    • Detailed Gene Information: Click Here.
  • Immunization Route: Intraperitoneal injection (i.p.)
Host Response

Fish Response

  • Persistence: A esrB mutant is attenuated in fish (Lan et al., 2007).
  • Efficacy: An esrB mutant induces significant protection in fish from challenge with wild type Edwardsiella tarda (Lan et al., 2007).
References
Lan et al., 2007: Lan MZ, Peng X, Xiang MY, Xia ZY, Bo W, Jie L, Li XY, Jun ZP. Construction and characterization of a live, attenuated esrB mutant of Edwardsiella tarda and its potential as a vaccine against the haemorrhagic septicaemia in turbot, Scophthamus maximus (L.). Fish & shellfish immunology. 2007; 23(3); 521-530. [PubMed: 17478097].