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Vaccine Detail
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Edwardsiella tarda esrB mutant vaccine |
| Vaccine Information |
- Vaccine Name: Edwardsiella tarda esrB mutant vaccine
- Target Pathogen: Edwardsiella tarda
- Vaccine Ontology ID: VO_0002833
- Type: Live, attenuated vaccine
- Status: Research
- Host Species as Laboratory Animal Model: Fish
- esrB
gene engineering:
- Type: Gene mutation
- Description: This esrB mutant is from Edwardsiella tarda (Lan et al., 2007).
- Detailed Gene Information: Click Here.
- Immunization Route: Intraperitoneal injection (i.p.)
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| Host Response |
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Fish Response
- Persistence: A esrB mutant is attenuated in fish (Lan et al., 2007).
- Efficacy: An esrB mutant induces significant protection in fish from challenge with wild type Edwardsiella tarda (Lan et al., 2007).
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| References |
Lan et al., 2007: Lan MZ, Peng X, Xiang MY, Xia ZY, Bo W, Jie L, Li XY, Jun ZP. Construction and characterization of a live, attenuated esrB mutant of Edwardsiella tarda and its potential as a vaccine against the haemorrhagic septicaemia in turbot, Scophthamus maximus (L.). Fish & shellfish immunology. 2007; 23(3); 521-530. [PubMed: 17478097].
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