|
|
Vaccine Detail
|
Edwardsiella tarda aroC mutant vaccine |
| Vaccine Information |
- Vaccine Name: Edwardsiella tarda aroC mutant vaccine
- Target Pathogen: Edwardsiella tarda
- Vaccine Ontology ID: VO_0002830
- Type: Live, attenuated vaccine
- Status: Research
- Host Species as Laboratory Animal Model: Zebra fish
- aroC
gene engineering:
- Type: Gene mutation
- Description: This aroC mutant is from Edwardsiella tarda (Xiao et al., 2011)
- Detailed Gene Information: Click Here.
- Immunization Route: Intramuscular injection (i.m.)
|
| Host Response |
|
Fish Response
- Persistence: An aroC mutant is attenuated in zebra fish (Xiao et al., 2011).
- Efficacy: An aroC mutant is protective in zebra fish against challenge from wild type E. tarda, resulting in a 68.3% relative percent survival (Xiao et al., 2011).
|
| References |
Xiao et al., 2011: Xiao J, Chen T, Wang Q, Liu Q, Wang X, Lv Y, Wu H, Zhang Y. Search for live attenuated vaccine candidate against edwardsiellosis by mutating virulence-related genes of fish pathogen Edwardsiella tarda. Letters in applied microbiology. 2011; ; . [PubMed: 21777261].
|
|
