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Vaccine Detail
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IHNV DNA vaccine pCMV4-N encoding the nucleoprotein |
| Vaccine Information |
- Vaccine Name: IHNV DNA vaccine pCMV4-N encoding the nucleoprotein
- Target Pathogen: Infectious Hematopoietic Necrosis Virus
- Target Disease: Infectious hematopoietic necrosis
- Vaccine Ontology ID: VO_0004322
- Type: DNA vaccine
- Status: Research
- Host Species as Laboratory Animal Model: Rainbow trout
- N gene
gene engineering:
- Type: DNA vaccine construction
- Description: Vector pCMV4 expressed the infectious hematopoietic necrosis virus (IHNV) nucleoprotein (Anderson et al., 1996).
- Detailed Gene Information: Click Here.
- DNA vaccine plasmid:
- DNA vaccine plasmid name:
- DNA vaccine plasmid VO ID: VO_0000217
- Immunization Route: Intramuscular injection (i.m.)
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| Host Response |
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Rainbow trout Response
- Vaccine Immune Response Type: VO_0000286
- Efficacy: Fish receiving pCMV4-N and pCMV4-G were protected from subsequent IHNV challenge (Anderson et al., 1996).
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| References |
Anderson et al., 1996: Anderson ED, Mourich DV, Fahrenkrug SC, LaPatra S, Shepherd J, Leong JA. Genetic immunization of rainbow trout (Oncorhynchus mykiss) against infectious hematopoietic necrosis virus. Molecular marine biology and biotechnology. 1996; 5(2); 114-122. [PubMed: 8680524].
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