|
|
Vaccine Detail
|
Classical swine fever virus DNA vaccine pCI-gp55 |
| Vaccine Information |
- Vaccine Name: Classical swine fever virus DNA vaccine pCI-gp55
- Target Pathogen: Classical swine fever virus
- Target Disease: Classical swine fever, hog cholera
- Vaccine Ontology ID: VO_0004340
- Type: DNA vaccine
- Status: Research
- Host Species as Laboratory Animal Model: Pig
- E2
gene engineering:
- Type: DNA vaccine construction
- Description: Vector pCI expressed the gp55/E2 gene from classical swine fever virus (CSFV) (Hammond et al., 2001).
- Detailed Gene Information: Click Here.
- DNA vaccine plasmid:
- DNA vaccine plasmid name:
- DNA vaccine plasmid VO ID: VO_0000212
- Immunization Route: Intramuscular injection (i.m.)
|
| Host Response |
|
Pig Response
- Vaccine Immune Response Type: VO_0000286
- Efficacy: Following challenge with CSFV, 100% of weaned pigs and 75% pre-weaned piglets were protected from disease (Hammond et al., 2001).
|
| References |
Hammond et al., 2001: Hammond JM, Jansen ES, Morrissy CJ, Goff WV, Meehan GC, Williamson MM, Lenghaus C, Sproat KW, Andrew ME, Coupar BE, Johnson MA. A prime-boost vaccination strategy using naked DNA followed by recombinant porcine adenovirus protects pigs from classical swine fever. Veterinary microbiology. 2001; 80(2); 101-119. [PubMed: 11295331].
|
|
