VIOLIN Logo
VO Banner
Search: for Help
About
Introduction
Statistics
VIOLIN News
Your VIOLIN
Register or Login
Submission
Tutorial
Vaccine & Components
Vaxquery
Vaxgen
VBLAST
Protegen
VirmugenDB
DNAVaxDB
CanVaxKB
Vaxjo
Vaxvec
Vevax
Huvax
Vaccine Mechanisms
Vaximmutordb
Vaxism
Vaxar
Vaccine Literature
VO-SciMiner
Litesearch
Vaxmesh
Vaxlert
Vaccine Design
Vaxign
Community Efforts
Vaccine Ontology
ICoVax 2012
ICoVax 2013
Advisory Committee
Vaccine Society
Vaxperts
VaxPub
VaxCom
VaxLaw
VaxMedia
VaxMeet
VaxFund
VaxCareer
Data Exchange
V-Utilities
VIOLINML
Help & Documents
Publications
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

Vaccine Detail

Vaccinia virus DNA vaccine 4pox
Vaccine Information
  • Vaccine Name: Vaccinia virus DNA vaccine 4pox
  • Target Pathogen: Vaccinia virus
  • Vaccine Ontology ID: VO_0004485
  • Type: DNA vaccine
  • Status: Research
  • Host Species as Laboratory Animal Model: Mouse
  • A27L gene engineering:
    • Type: DNA vaccine construction
    • Description: Vector pWRG/TPA expressed VACV A27L (Hooper et al., 2007).
    • Detailed Gene Information: Click Here.
  • L1R gene engineering:
    • Type: DNA vaccine construction
    • Description: This vaccine expressed L1R (Hooper et al., 2007).
    • Detailed Gene Information: Click Here.
  • A33R gene engineering:
    • Type: DNA vaccine construction
    • Description: This vaccine expressed A33R (Hooper et al., 2007).
    • Detailed Gene Information: Click Here.
  • B5R gene engineering:
    • Type: DNA vaccine construction
    • Description: This vaccine expressed B5R (Hooper et al., 2007).
    • Detailed Gene Information: Click Here.
  • DNA vaccine plasmid: pWRG7077 DNA vaccine plasmid
  • Immunization Route: Intramuscular injection (i.m.)
Host Response

Mouse Response

  • Vaccine Immune Response Type: VO_0000286
  • Efficacy: Vaccinated mice were completely protected against a lethal (>10LD(50)) intranasal challenge with vaccinia virus strain IHD-J (Hooper et al., 2007).
References
Hooper et al., 2007: Hooper JW, Golden JW, Ferro AM, King AD. Smallpox DNA vaccine delivered by novel skin electroporation device protects mice against intranasal poxvirus challenge. Vaccine. 2007; 25(10); 1814-1823. [PubMed: 17240007].