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Vaccine Detail

Sindbis virus DNA vaccine encoding E2
Vaccine Information
  • Vaccine Name: Sindbis virus DNA vaccine encoding E2
  • Target Pathogen: Sindbis virus
  • Target Disease: Encephalitis
  • Vaccine Ontology ID: VO_0004491
  • Type: DNA vaccine
  • Status: Research
  • Host Species as Laboratory Animal Model: Mouse
  • E2 gene engineering:
    • Type: DNA vaccine construction
    • Description: Vector pCI-neo expressed the SV E2 gene with an upstream Kozak sequence and a downstream FLAG tag (Zanin et al., 2007).
    • Detailed Gene Information: Click Here.
  • DNA vaccine plasmid: pCI-neo DNA vaccine plasmid
  • Immunization Route: Intramuscular injection (i.m.)
Host Response

Mouse Response

  • Vaccine Immune Response Type: VO_0000286
  • Efficacy: This vaccination strategy was immunogenic and provided partial protection against viral encephalitis in a murine model (Zanin et al., 2007).
References