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Vaccine Detail
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C. pneumoniae DNA vaccine pHSP-60 |
| Vaccine Information |
- Vaccine Name: C. pneumoniae DNA vaccine pHSP-60
- Target Pathogen: Chlamydophila pneumoniae
- Target Disease: Pneumonia
- Vaccine Ontology ID: VO_0004555
- Type: DNA vaccine
- Status: Research
- Host Species as Laboratory Animal Model: Mouse
- GroEL
gene engineering:
- Type: DNA vaccine construction
- Description:
- Detailed Gene Information: Click Here.
- DNA vaccine plasmid:
- DNA vaccine plasmid name:
- DNA vaccine plasmid VO ID: VO_0000212
- Immunization Route: intranasal immunization
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| Host Response |
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Mouse Response
- Vaccine Immune Response Type: VO_0003057
- Efficacy: Immunization with this vaccine resulted in signi®cant protection, as measured by a lower bacterial load and a less severe pathological outcome after infection with C. pneumoniae (Svanholm et al., 2000).
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| References |
Svanholm et al., 2000: Svanholm C, Bandholtz L, Castaños-Velez E, Wigzell H, Rottenberg ME. Protective DNA immunization against Chlamydia pneumoniae. Scandinavian journal of immunology. 2000; 51(4); 345-353. [PubMed: 10736106].
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