• Vaccine Name: rMV- WNV
• Target Pathogen: West Nile virus
• Target Disease: West Nile fever
• Vaccine Ontology ID: VO_0004712
• Type: Recombinant vector vaccine
• Status: Research
• Host Species for Licensed Use: Baboon
• Vector:
  • Vector name:
  • VO vector ID: VO_0001056
• Preparation: A recombinant MV vaccine expressing the secreted form of WNV envelope glycoprotein (Brandler and Tangy, 2013).
• Immunization Route: Intramuscular injection (i.m.)

Mouse Response

• Vaccination Protocol: Mice were immunized with varying doses of MVSchw-sEWN (Brandler and Tangy, 2013).
• Vaccine Immune Response Type: VO_0003057
• Challenge Protocol: Mice were challenged with doses ranging from 100 to 100,000 focus-forming units of IS98-ST1 WNV (Brandler and Tangy, 2013).
• Efficacy: A single administration of a recombinant MV vaccine expressing the secreted form of WNV envelope glycoprotein elicited protective immunity in mice as early as two weeks after immunization (Brandler and Tangy, 2013).