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Vaccine Detail

Toxminus-PLD toxoid
Vaccine Information
  • Vaccine Name: Toxminus-PLD toxoid
  • Target Pathogen: Corynebacterium pseudotuberculosis
  • Vaccine Ontology ID: VO_0004795
  • Type: Recombinant vector vaccine
  • Status: Research
  • Host Species for Licensed Use: Baboon
  • Vector:
  • Preparation: (Hodgson et al., 1994) An inactive form of the Corynebacterium pseudotuberculosis phospholipase D (PLD) gene was constructed and expressed in a PLD-negative strain (designated Toxminus) of C. pseudotuberculosis.
  • Immunization Route: Intramuscular injection (i.m.)
Host Response
References
Hodgson et al., 1994: Hodgson AL, Tachedjian M, Corner LA, Radford AJ. Protection of sheep against caseous lymphadenitis by use of a single oral dose of live recombinant Corynebacterium pseudotuberculosis. Infection and immunity. 1994; 62(12); 5275-5280. [PubMed: 7960105].