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Vaccine Detail

RE
Vaccine Information
  • Vaccine Name: RE
  • Target Pathogen: Influenza virus
  • Target Disease: Influenza (flu)
  • Type: Live, attenuated vaccine
  • Status: Licensed
  • Host Species for Licensed Use: Baboon
  • Immunization Route: Intramuscular injection (i.m.)
  • Description: lyophilized whole virion preparation of inactivated influenza virus (Momose et al., 2015).
Host Response

Mouse Response

  • Vaccination Protocol: Eight week-old male Wistar rats weighing 160–200 g were obtained from SLC (Tokyo, Japan). Rats were housed in rooms maintained at 23 ± 1°C, with 50 ± 10% relative humidity, and 12 h light/dark cycles for at least one week prior to the test challenge (Momose et al., 2015).
  • Host Ifi47 response
    • Description: RE induced upregulation of IFI47 in lung lysates on day 7 (Momose et al., 2015).
    • Detailed Gene Information: Click Here.
  • Host Ifi47 response
    • Description: RE induced upregulation of IFI47 in lung lysates on day 7 (Momose et al., 2015).
    • Detailed Gene Information: Click Here.
  • Host Ifi47 response
    • Description: RE induced upregulation of IFI47 in lung lysates on day 7 (Momose et al., 2015).
    • Detailed Gene Information: Click Here.
  • Host Ifi47 response
    • Description: RE induced upregulation of IFI47 in lung lysates on day 7 (Momose et al., 2015).
    • Detailed Gene Information: Click Here.
  • Host Ifi47 response
    • Description: RE induced upregulation of IFI47 in lung lysates on day 7 (Momose et al., 2015).
    • Detailed Gene Information: Click Here.
  • Host Ifi47 response
    • Description: RE induced upregulation of IFI47 in lung lysates on day 7 (Momose et al., 2015).
    • Detailed Gene Information: Click Here.
  • Host LGALS9 response
    • Description: RE induced upregulation of LGALS9 in lung lysates on day 7 (Momose et al., 2015).
    • Detailed Gene Information: Click Here.
  • Host MX2 response
    • Description: RE induced upregulation of MX2 in lung lysates on day 7 (Momose et al., 2015).
    • Detailed Gene Information: Click Here.
  • Host ZBP1 response
    • Description: RE induced upregulation of ZBP1 in lung lysates on day 7 (Momose et al., 2015).
    • Detailed Gene Information: Click Here.
References
Momose et al., 2015: Momose H, Mizukami T, Kuramitsu M, Takizawa K, Masumi A, Araki K, Furuhata K, Yamaguchi K, Hamaguchi I. Establishment of a new quality control and vaccine safety test for influenza vaccines and adjuvants using gene expression profiling. PloS one. 2015; 10(4); e0124392. [PubMed: 25909814].