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Vaccine Detail

5CVMB
Vaccine Information
  • Vaccine Name: 5CVMB
  • Target Pathogen: Neisseria meningitidis
  • Target Disease: Meningitis
  • Vaccine Ontology ID: VO_0011348
  • Type: Subunit vaccine
  • Status: Licensed
  • Antigen: Five antigens are included: GNA2132, GNA1870, NadA, GNA1030, and GNA2091 (Giuliani et al., 2006)
  • Adjuvant: aluminum hydroxide vaccine adjuvant
  • Adjuvant: CpG DNA vaccine adjuvant
  • Immunization Route: Intraperitoneal injection (i.p.)
Host Response
References
Giuliani et al., 2006: Giuliani MM, Adu-Bobie J, Comanducci M, Aricò B, Savino S, Santini L, Brunelli B, Bambini S, Biolchi A, Capecchi B, Cartocci E, Ciucchi L, Di Marcello F, Ferlicca F, Galli B, Luzzi E, Masignani V, Serruto D, Veggi D, Contorni M, Morandi M, Bartalesi A, Cinotti V, Mannucci D, Titta F, Ovidi E, Welsch JA, Granoff D, Rappuoli R, Pizza M. A universal vaccine for serogroup B meningococcus. Proceedings of the National Academy of Sciences of the United States of America. 2006; 103(29); 10834-10839. [PubMed: 16825336].